Micro U2 L3. Flashcards

1
Q

What type of virus are arboviruses?

A

RNA virus (from arthropods - mostly mosquitoes and ticks)

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2
Q

What are the 4 clinical syndromes that arboviruses can cause?

A
  1. systemic febrile illness 2. fever with arthritis 3. encephalitis 4. hemorrhagic fever
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3
Q

Eastern Equine Encephalitis (EEE) - family and genera

A

family: togaviridae; genera: alphavirus

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4
Q

How many encephalitic viruses are in the alphavirus genus? What are they?

A

4 - EEE (east US), WEE (west US), VEE (SA and NA), everglades

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5
Q

Why is EEE clinically important?

A

highest probability for developing encephalitis from the encephalitic viruses and also highest mortality rate —> CICERO SWAMP!

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6
Q

What are the vectors for EEE?

A

migrating birds and mosquitos - human is a dead end host

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7
Q

Japanese encephalitis virus natural host

A

pig and migrating birds - human is accidental host

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8
Q

How is Japanese encephalitis virus diagnosed?

A

travel history

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9
Q

Which arbovirus has a vaccine?

A

Japanese encephalitis virus

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10
Q

When is Japanese encephalitis virus transmitted?

A

all year long - culex mosquitos (night feeders)

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11
Q

Japanese encephalitis virus symptoms

A

encephalitis with high mortality and morbidity

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12
Q

Yellow fever virus family and genus

A

flaviviridiae, flavivirus

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13
Q

Where did yellow fever originate?

A

africa - divided into west and east african lineages (W africa is the one that spread)

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14
Q

Life cycles of yellow fever

A

both zoonotic and urban cycles (monkey -> mosquito -> human and human -> mosquito ->human)

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15
Q

What does yellow fever cause?

A

hemorrhagic disease

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16
Q

Dengue fever family and genus

A

flaviviridiae and flavivirus (same as yellow fever)

17
Q

Clinical syndroms Dengue fever

A

febrile illness to severe hemorrhagic fever (SHOCK SYNDROME)

18
Q

What is the most common arboviral disease in the subtropical and tropical regions of the world?

A

dengue fever (including Key West in the US)

19
Q

What is a sign of Dengue fever?

A

petechiae

20
Q

What is the pathology of Japanese encephalitis virus?

A

febrile headache -> aseptic meningitis -> encephalitis