Micro U2 L3. Flashcards
What type of virus are arboviruses?
RNA virus (from arthropods - mostly mosquitoes and ticks)
What are the 4 clinical syndromes that arboviruses can cause?
- systemic febrile illness 2. fever with arthritis 3. encephalitis 4. hemorrhagic fever
Eastern Equine Encephalitis (EEE) - family and genera
family: togaviridae; genera: alphavirus
How many encephalitic viruses are in the alphavirus genus? What are they?
4 - EEE (east US), WEE (west US), VEE (SA and NA), everglades
Why is EEE clinically important?
highest probability for developing encephalitis from the encephalitic viruses and also highest mortality rate —> CICERO SWAMP!
What are the vectors for EEE?
migrating birds and mosquitos - human is a dead end host
Japanese encephalitis virus natural host
pig and migrating birds - human is accidental host
How is Japanese encephalitis virus diagnosed?
travel history
Which arbovirus has a vaccine?
Japanese encephalitis virus
When is Japanese encephalitis virus transmitted?
all year long - culex mosquitos (night feeders)
Japanese encephalitis virus symptoms
encephalitis with high mortality and morbidity
Yellow fever virus family and genus
flaviviridiae, flavivirus
Where did yellow fever originate?
africa - divided into west and east african lineages (W africa is the one that spread)
Life cycles of yellow fever
both zoonotic and urban cycles (monkey -> mosquito -> human and human -> mosquito ->human)
What does yellow fever cause?
hemorrhagic disease