Micro - Shit Not In Sketchy Flashcards by Alex Hamidi

What causes lymphatic filariasis?

Vector?

Tx?

Wuchereria bancrofti

Female mosquito

Diethylcarbamazine

How well did you know this?

Not at all

Perfectly

The IM vaccine for Salmonella typhi contains what?

Oral?

Vi capsular polysaccharide

Live attenuated

How well did you know this?

Not at all

Perfectly

What causes trophozoites w/engulfed RBCs in the cytoplasm?

Entamoeba histolytica

How well did you know this?

Not at all

Perfectly

MOA of M protein?

Prevents phagocytosis

How well did you know this?

Not at all

Perfectly

Schuffner stippling throught rbc cytoplasm seen in what infection?

P vivax/ovale

How well did you know this?

Not at all

Perfectly

Which nematodes bite?

lay LOW
Loa loa
Onchocerca volvulus
Wucheria bancrofti

How well did you know this?

Not at all

Perfectly

Eaton agar on what?

M pneumoniae

How well did you know this?

Not at all

Perfectly

What infection causes hypopigmented and hyperpigmented and/or pink patches, more common in summer?

Malassezia species (Pityrosporum)

How well did you know this?

Not at all

Perfectly

What needs cholesterol for gram stain?

Mycobacterium

How well did you know this?

Not at all

Perfectly

3 main effects of endotoxin?

Macrophage activation (TLR4)
Complement activation
tissue factor activation

How well did you know this?

Not at all

Perfectly

Pseudomonas produces what 4 virulence factors?

Pyocyanin (makes ROS)
Endotoxin
Exotoxin A (inactivates EF-2)
Phospholipase C (degrades cell membranes)

How well did you know this?

Not at all

Perfectly

What organism causes vomiting, diarrhea, epigastric pain and is found in the soil?

What is seen under microscope?

Tx?

Strongyloides

Rhabditiform larvae

Ivermectin

How well did you know this?

Not at all

Perfectly

What is Bordet-Gengou agar used for?

What media?

B. Pertussis

Potato extract

How well did you know this?

Not at all

Perfectly

What makes up thayer-martin agar?

Vancomycin
TMP
Colistin
Nystatin

How well did you know this?

Not at all

Perfectly

Which bacteria is (+) for Hippurate test?

Grp B strep

How well did you know this?

Not at all

Perfectly

Which nematodes are cutaneous?

SANd
Strongyloides
Ascaris
Necator

How well did you know this?

Not at all

Perfectly

What g(+) bacteria are gamma hemolytic?

Enterococci

Strep bovis

How well did you know this?

Not at all

Perfectly

What organism is dx by knobby-coated oval eggs seen in feces?

Can cause what sx?

Ascaris lumbricoides

SBO, biliary obstruction

How well did you know this?

Not at all

Perfectly

What creates a serpentine cord appearance in virulent M. TB?

Activates what? Induces what?

Cord factor

Macrophages that induces release of TNF-a

How well did you know this?

Not at all

Perfectly

What g(+) bacteria can grow in 6.5% NaCl and bile?

(+) for what else?

Enterococci

PYR (bacitracin sensitive)

How well did you know this?

Not at all

Perfectly

What organisms can be stained with silver?

Coccidioides
PCP
Legionella
H. Pylori

How well did you know this?

Not at all

Perfectly

What causes loose stools and rectal prolapse in children?

Trichuris Trichiura

How well did you know this?

Not at all

Perfectly

How do you treat pedicures humanus (lice)?

Pyrethroids

Ivermectin lotion

Regan-Lowe medium used to visualize what?

Media contains what?

Bordatella pertussis

Charcoal, blood, Antibiotic

What bacteria have IgA protease? How does it work?

S pneum, H influ Type B, Neisseria Cleaves IgA, allows bacteria to adhere to and colonize mucous membranes

What indicates a recent S pyogenes infection?

ASO titer or anti-DNase B antibodies

What M Tb component inhibits phagolysosomal function?

Suflatides (surface glycolipids)

What are the conjugated vaccines? How do they increase immunogenicity?

Pneumococcal PCV13 w/conjugate Pneumococcal PPSV23 w/no conjugate H influ Meningococcal

What organisms take up Giemsa stain?

``` Chlamydia Borrelia Rickettsia Trypanosomes Plasmodium ```

TSST-1 of S aureus binds to what to cause symptoms?

MHC II and TCR

What aerobic diplococci utilizes maltose? What does not?

N meningitidis N gonorrhea, Moraxella

What is a type III secretion system? Found in what bacteria?

Aka injectisome, needle-like protein appendage facilitating direct delivery of toxins from certain g (-) bacteria to eukaryotic host cell Grade (-) like Pseudomonas, E coli, Shigella

What are the fast lactose fermenters?

KEE Klebsiella E coli Enterobacter

What can be used to treat C diff, but is not metronidazole or Oral Vancomycin? MOA?

Fidaxomicin Inhibits sigma subunit of RNA Pol

What causes hydatid cysts and eggshell calcification? Ingestion how? What is the intermediate host?

Echinococcus granulosus Eggs in food contaminated w/dog feces Sheep

What virulence factor binds Fc region of IgG and prevents phagocytosis and opsonization? Expressed by what?

Protein A S aureus

How to visualize Tinea (dermatophytes)? What will you see?

KOH prep w/blue fungal stain Branching septate hyphae visible

What is (+) for H2S production on TSI agar? (-)?

Salmonella, proteus Shigella, Yersenia

Fever, vomiting, nausea, periorbital edema, and myalgia is characteristic of what infection? Obtained how?

Trichinosis --> Trichinella spiralis Undercooked meat --> esp pork

Sarcoptes scabiei are found in what layer? Commonly occur where? Tx?

Stratum corneum Jails, nursing homes Permethrin cream

What is the transmission of loa loa? Tx?

Deer fly, horse fly, mango fly Diethylcarbamazine

What causes cigar-shaped budding yeast that causes skin pustules or ulcers? Tx?

Sporothrix schenckii Itraconazole, KI

Which bacteria can undergo specialized Lysogenic phage transduction?

``` CO BEDS Cholera O Ag of Salmonella Botulinum Erythrogenic toxin of S pyogenes Diptheria Shiga toxin ```

What organisms cause anemia by sucking blood from the intestinal wall and the larvae penetrate the skin?

Ancylostoma duodenal | Necator americanus

What kind of hemolysis results in greenish or brownish color w/out clearing around growth on blood agar?

Alpha-hemolytic | S pneumo, S viridans

What infections specifically causes onychomycosis?

Tinea unguium

Infection of what is diagnosed by trypomastigote in blood smear? Tx:

Trypanosoma brucei Suramin for blood borne disease Melarsoprol for CNS penetration

What are the anaerobic bacteria?

``` Can't Breathe Fresh Air Clostridium Bacteriodes Fusobacterium Actinomycetes ```

What grows on EMB agar?

E coli

How to treat onchocerca volvulus (river blindness)?

Ivermectin

How to treat tinea versicolor (pityriasis)?

Selenium sulfide

Macrophages containing amastigotes is dx of what? Vector?

Leishmania donovani Sandfly

What is diagnosed by a biopsy w/tachyzoite?

Toxoplasmosis gondii P. 152

Which nematodes can be ingested?

``` EATT Enterovirus Ascaris Toxocara Trichinella ```

What infection is dx on blood smear w/trophozoite ring form within a rbc?

Plasmodium species

How to acquire tinea capitis?

Infected cat or dog