Micro Pharm

Question 1

Resistance to tetracyclines, flouroquinolones

Answer 1

Increased drug efflux pump
(new membrane transport system)

Question 2

Resistance to penicillins, cephalosporins

Answer 2

Drug-inactivating enzyme
(beta-lactamase)

Question 3

Resistance to aminoglycosides

Answer 3

Drug inactivating enzyme
(acetyltransferase)

Question 4

Resistance to penicillins, flouroquinolones

Answer 4

Decreased drug uptake
(mutated porin protein)

Question 5

Resistance to penicillins

Answer 5

Modified drug target
(altered penicillin-binding protein)

Question 6

Resistance to aminoglycosides, macrolides

Answer 6

Modified drug target
(altered ribosomal protein)

Question 7

Resistance to flouroquinolones

Answer 7

Modified drug target
(altered DNA gyrase)