Micro Hockey Antibiotics Q's

Question 1

Give examples of antibiotics that inhibit petidoglycan cell wall synthesis?

What bacteria can they be used to treat?

Answer 1

B-lactams
Penicillin
Cephalosporin
Carbepenines (imipenem (pseudomonas aeruginosa))

Glycopeptides
Vancomycin (MRSA, C.Diff)

Question 2

What can the different penicillins be used to treat?

Answer 2

Benzylpenicllin (strep)

Flucloxicilin (staph)

Amoxicillin (RTI)

Question 3

What can the different cephalosporin be used to treat?

Answer 3

1st gen
Cefradoxil, cefradine

2nd gen
Cefuroxime (Neisseria, h influenza)

3rd gen
Cefutaxime (meninigitis), cefuxime

Question 4

Give examples of antibiotics that inhibit nucleotide acid synthesis?

Give the part of nucleotide acid synthesis that they inhibit?

Answer 4

Inhibit folate synth:
Trimpethoprim (UTI, tetratrogenic)
Sulfonamides
Co-Trimoxazole (trimethoprim+ sulfonamide)

Inhibit DNA gyrase
Fluroquinones- cirprofloxicin

RNA polymerase
Rifampicin

DNA strand breaks
Metronidazole

Question 5

Give exmaples of antibiotics that inhibit protein synthesis?

Give the diseases that they are used to treat?

Answer 5

Chloroamphenicol

Macrolides
Clarithryomycin
Erthyromycin (pregnant chlamydia)
Azithromycin (chlamydia)

Tetracyclines
Tetracycline
Doxycycline (acne, antimalarial)

Aminoglycoside
Gentamicin
Streptomycin (sepsis)