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2a Bateman - Phase 2a MASTER DECK > Drugs > Flashcards

Drugs Flashcards

1
Q

What class of drug is alendronate?

A

Bisphosphonate

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2
Q

What class of drug is atenolol?

A

Beta-blocker

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3
Q

What class of drug is atracurium?

A

Non-depolarising neuromuscular blocker

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4
Q

What class of drug is bendro-flumethiazide?

A

Thiazide Diuretic

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5
Q

What class of drug is cefuroxime?

A

Cephalosporin antibiotic (2nd generation)

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6
Q

What class of drug is celecoxib?

A

NSAID

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7
Q

What class of drug is chloramphenicol?

A

Antibiotic

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8
Q

What class of drug is ciclosporin?

A

Immunosuppresant

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9
Q

What class of drug is ciprofloxacin?

A

Quinolone antibiotic

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10
Q

What class of drug is co-amoxiclav?

A

Combination antibiotic

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11
Q

What class of drug is diamorphine?

A

Opioid analgesic

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12
Q

What class of drug is dalteparin?

A

LMW Heparin

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13
Q

What class of drug is dobutamine?

A

Beta-adrenergic agonist.

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14
Q

What class of drug is doxazosin?

A

Alpha1-selective alpha blocker

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15
Q

What class of drug is ephedrine?

A

Alpha and Beta adrenergic agonist

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16
Q

What class of drug is erythromycin?

A

Macrolide antibiotic

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17
Q

What class of drug is ethinylestradiol?

A

Oestrogen

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18
Q

What class of drug is furosemide?

A

Loop diuretic

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19
Q

What class of drug is ipratropium?

A

Muscarinic agonist

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20
Q

What class of drug is loperamide?

A

Opioid-receptor agonist

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21
Q

What class of drug is metformin?

A

Anti-hyperglycaemic

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22
Q

What class of drug is methotrexate?

A

DMARD

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23
Q

What class of drug is oxybutinin?

A

Anticholinergic

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24
Q

What class of drug is paracetamol?

A

Analgesic antipyretic

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25
Q

What class of drug is ramipril?

A

ACE-Inhibitor

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26
Q

What class of drug is rifampicin?

A

Semisynthetic antibiotic

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27
Q

What class of drug is rivaroxiban?

A

Anticoagulant

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28
Q

What class of drug is salmeterol?

A

Beta-2-agonist

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29
Q

What class of drug is sildenafil?

A

cGMP-specific PDE5 inhibitor

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30
Q

What class of drug is suxamethonium?

A

Paralytic

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31
Q

What class of drug is tamsulosin?

A

Alpha blocker

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32
Q

What class of drug is tramadol?

A

Opioid

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33
Q

What is the indication for aldendronate?

A

Osteoporosis
Paget’s disease
Osteogenesis Imperfecta (>18yrs)

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34
Q

What is the indications for atenolol?

A 
Hypertension
Angina
Arrhythmias
Alcohol withdrawal syndrome
Myocardial infarction
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35
Q

What is the indication for atracurium?

A

Neuromuscular blockade

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36
Q

What is the indication for bender-flumethiazide?

A

Hyperkalaemia
Hypertension
Oedema
Urinary tract disorders

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37
Q

What is the indication for cefuroxime?

A

Gram-negative and gram-positive infections
Gonorrhoea
Haemophilus
CNS infections

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38
Q

What is the indication for celecoxib?

A 
Osteoarthritis
Rheumatoid arthritis
Ankylosing spondylitis
Acute pain
Colorectal polyps
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39
Q

What is the indication for chlorampenicol?

A

Conjunctivitis
Meningitis, plague, cholera, typhoid
Broad spectrum

40
Q

What is the indication for ciclosporin?

A 
Rheumatoid arthritis
Psoriasis
Crohn's disease
Nephrotic syndrome
Organ transplant
Keratitis
41
Q

What is the indication for ciprofloxacin?

A 
Gram positives
Staphylococci
Enterococci
Pneumococci
Streptococci
42
Q

What is the indication for co-amoxiclav?

A

H. Influenzae
N. Gonorrhoea
Enterobacteriacae

43
Q

What is the indication for diamorphine?

A

Acute or chronic pain
Pulmonary oedema
Myocardial Infarction

44
Q

What is the indication for dalteparin?

A

Unstable angina
Pulmonary embolism
Deep vein thrombosis
DVT prophylaxis

45
Q

What is the indication for dobutamine?

A

Coronary artery disease, MI
Cardiac surgery
Septic/cardio shock
Cardiomyopathies

46
Q

What is the indication for doxazosin?

A

Hypertension

Benign prostatic hyperplasia

47
Q

What is the indication for ephedrine?

A

Reversal of hypotension from anaesthesia
Airway obstruction
Neuropathic oedema
Nasal congestion

48
Q

What is the indication for erythromycin?

A

Enteric bacteria
Strep. Pyogenes
H. Influenzae
Staph. Aureus

49
Q

What is the indication for ethinylestradiol?

A

Menstrual disorders
F hypogonadism
Osteoporosis prophyl.
Prostate cancer

50
Q

What is the indication for furosemide?

A

Hypertension
Oedema related to: Heart Failure
Renal disease
Liver cirrhosis

51
Q

What is the indication for ipratropium?

A

COPD
Asthma
Rhinorrhoea

52
Q

What is the indication for loperamide?

A

Diarrhoea
Inflammatory bowel disease
IBS

53
Q

What is the indication for metformin?

A

Diabetes

Polycystic ovary syndrome

54
Q

What is the indication for methotrexate?

A

Rheumatoid arthritis
Crohn’s disease
Neoplastic diseases
Severe psoriasis

55
Q

What is the indication for oxybutinin?

A

Urinary frequency, urgency & incontinence

Neurogenic bladder dysfunction

56
Q

What is the indication for paracetamol?

A

Fever

Pain

57
Q

What is the indication for ramipril?

A

Heart Failure
Hypertension
MI, Stroke
Nephropathy

58
Q

What is the indication for rifampicin?

A 
TB
Leprosy
Legionnaire's
H. influenza
Meningococcus
59
Q

What is the indication for rivaroxiban?

A

DVT
PE
Stroke

60
Q

What is the indication for salmeterol?

A

Asthma

COPD

61
Q

What is the indication for sildenafil?

A

Erectile dysfunction

Pulmonary hypertension

62
Q

What is the indication for suxamethonium?

A

General Anaesthesia - Surgery

63
Q

What is the indication for tamsulosin?

A

Benign prostatic hyperplasia

64
Q

What is the indication for tramadol?

A

Moderate to severe pain

65
Q

What is the action of alendronate?

A

Inhibits osteoclast mediated bone resorption by inhibiting the enzyme FPP synthase

66
Q

What is the action of atenolol?

A

Binds to beta-adrenergic receptors in the heart and vascular smooth muscle, inhibiting sympathetic stimulation

67
Q

What is the action of atracurium?

A

Binds competitively with cholinergic receptor sites to antagonise acetylcholine action

68
Q

What is the action of bendro-flumethiazide?

A

Inhibits Cl reabsorption at early distal tubule, results in increase of Na, Cl and water excretion

69
Q

What is the action of cefuroxime?

A

Inhibition of bacterial cell wall synthesis -> death due to lysis

70
Q

What is the action of celecoxib?

A

Inhibits Cox-2 cyclooxygenase -> inhibits prostaglandin synthesis

71
Q

What is the action of chlorampenicol?

A

Bacteriostatic - inhibits protein synthesis by interfering with substrate binding

72
Q

What is the action of ciclosporin?

A

Decreases lymphocyte function

Binds to cytosolic protein, inhibiting calcineurin -> less inflammatory cytokine production

73
Q

What is the action of ciprofloxacin?

A

Inhibition of bacterial DNA gyrase enzyme -> prevents DNA replication so stops replication

74
Q

What is the action of co-amoxiclav?

A

Beta-lactamase inhibitor + inhibits penicillin binding proteins -> inhibits bacterial cell wall synthesis

75
Q

What is the action of diamorphine?

A

Mu-opioid agonist

Acts on receptors in the CNS which produces an analgesic effect

76
Q

What is the action of dalteprain?

A

Inhibits the formation of factor Xa and thrombin

77
Q

What is the action of dobutamine?

A

Directly stimulates Beta-1 receptors in the heart, increases myocardial contractility and stroke volume

78
Q

What is the action of doxazosin?

A

Inhibits postsynaptic alpha 1 adrenoceptors on vascular smooth muscle - peripheral vasodilation

79
Q

What is the action of ephedrine?

A

Stimulation of adrenergic receptors

Increases noradrenaline action and release

80
Q

What is the action of erythromycin?

A

Inhibits bacterial protein synthesis

Bacteriostatic/cidal dependent on dose

81
Q

What is the action of ethinylestradiol?

A

Interaction with oestrogen receptors in target cells

82
Q

What is the action of furosemide?

A

Inhibits water reabsorption in the nephron (blocks Na-K-Cl cotransporter)

83
Q

What is the action of ipratropium?

A

Blocks muscarinic ACh receptors, promoting cGMP degradation - reduces bronchoconstriction

84
Q

What is the action of loperamide?

A

Acts on mu-opioid receptors in PNS -> slows intestinal motility
Doesn’t cross the BBB so can’t affect CNS

85
Q

What is the action of metformin?

A

Decreases hepatic glucose production and intestinal glucose absorption
Improves insulin sensitivity

86
Q

What is the action of methotrexate?

A

Cancer - inhibition of DHFR, inhibiting folate synthesis.

Arthritis - inhibition of purine metabolism = accumulation of adenosine = suppression of T cells

87
Q

What is the action of oxybutin?

A

Antagonist of M1, 2 & 3 muscarinic ACh receptors

Decreases muscle spasms of the bladder

88
Q

What is the action of paracetamol?

A

COX enzyme inhibition in CNS indirectly

89
Q

What is the action of ramipril?

A

Inhibit ACE activity
Less Angiotensin II produced
Less Bradykinin breakdown
Relaxation of arterial smooth muscle

90
Q

What is the action of rifampicin?

A

Inhibits bacterial RNA polymerase enzyme - no RNA synthesis

91
Q

What is the action of rivaroxiban?

A

Competitive irreversible inhibition of factor Xa.

Prevents thrombin formation

92
Q

What is the action of salmeterol?

A

Beta 2 stimulation causes relaxation of bronchial smooth muscle

93
Q

What is the action of sildenafil?

A

Increases cGMP to cause smooth muscle relaxation - vasodilation

94
Q

What is the action of suxamethonium?

A

Mimics ACh at NM junction, with slow hydrolysis - prolongs depolarisation = NM blockade

95
Q

What is the action of tamsulosin?

A

Selective A1 antagonist

Causes relaxation in smooth muscle = less resistance to urinary flow=less pain in BPH

96
Q

What is the action of tramadol?

A

Agonist of mu-opioid receptors
Serotonin & norepinephrine reuptake inhibitor
Enhances serotonin release

2a Bateman - Phase 2a MASTER DECK (24 decks)

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