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2a Bateman - Phase 2a MASTER DECK > Drugs > Flashcards

Drugs Flashcards

1
Q

What class of drug is alendronate?

A

Bisphosphonate

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2
Q

What class of drug is atenolol?

A

Beta-blocker

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3
Q

What class of drug is atracurium?

A

Non-depolarising neuromuscular blocker

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4
Q

What class of drug is bendro-flumethiazide?

A

Thiazide Diuretic

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5
Q

What class of drug is cefuroxime?

A

Cephalosporin antibiotic (2nd generation)

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6
Q

What class of drug is celecoxib?

A

NSAID

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7
Q

What class of drug is chloramphenicol?

A

Antibiotic

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8
Q

What class of drug is ciclosporin?

A

Immunosuppresant

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9
Q

What class of drug is ciprofloxacin?

A

Quinolone antibiotic

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10
Q

What class of drug is co-amoxiclav?

A

Combination antibiotic

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11
Q

What class of drug is diamorphine?

A

Opioid analgesic

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12
Q

What class of drug is dalteparin?

A

LMW Heparin

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13
Q

What class of drug is dobutamine?

A

Beta-adrenergic agonist.

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14
Q

What class of drug is doxazosin?

A

Alpha1-selective alpha blocker

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15
Q

What class of drug is ephedrine?

A

Alpha and Beta adrenergic agonist

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16
Q

What class of drug is erythromycin?

A

Macrolide antibiotic

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17
Q

What class of drug is ethinylestradiol?

A

Oestrogen

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18
Q

What class of drug is furosemide?

A

Loop diuretic

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19
Q

What class of drug is ipratropium?

A

Muscarinic agonist

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20
Q

What class of drug is loperamide?

A

Opioid-receptor agonist

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21
Q

What class of drug is metformin?

A

Anti-hyperglycaemic

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22
Q

What class of drug is methotrexate?

A

DMARD

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23
Q

What class of drug is oxybutinin?

A

Anticholinergic

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24
Q

What class of drug is paracetamol?

A

Analgesic antipyretic

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25
What class of drug is ramipril?
ACE-Inhibitor
26
What class of drug is rifampicin?
Semisynthetic antibiotic
27
What class of drug is rivaroxiban?
Anticoagulant
28
What class of drug is salmeterol?
Beta-2-agonist
29
What class of drug is sildenafil?
cGMP-specific PDE5 inhibitor
30
What class of drug is suxamethonium?
Paralytic
31
What class of drug is tamsulosin?
Alpha blocker
32
What class of drug is tramadol?
Opioid
33
What is the indication for aldendronate?
Osteoporosis Paget's disease Osteogenesis Imperfecta (>18yrs)
34
What is the indications for atenolol?
``` Hypertension Angina Arrhythmias Alcohol withdrawal syndrome Myocardial infarction ```
35
What is the indication for atracurium?
Neuromuscular blockade
36
What is the indication for bender-flumethiazide?
Hyperkalaemia Hypertension Oedema Urinary tract disorders
37
What is the indication for cefuroxime?
Gram-negative and gram-positive infections Gonorrhoea Haemophilus CNS infections
38
What is the indication for celecoxib?
``` Osteoarthritis Rheumatoid arthritis Ankylosing spondylitis Acute pain Colorectal polyps ```
39
What is the indication for chlorampenicol?
Conjunctivitis Meningitis, plague, cholera, typhoid Broad spectrum
40
What is the indication for ciclosporin?
``` Rheumatoid arthritis Psoriasis Crohn's disease Nephrotic syndrome Organ transplant Keratitis ```
41
What is the indication for ciprofloxacin?
``` Gram positives Staphylococci Enterococci Pneumococci Streptococci ```
42
What is the indication for co-amoxiclav?
H. Influenzae N. Gonorrhoea Enterobacteriacae
43
What is the indication for diamorphine?
Acute or chronic pain Pulmonary oedema Myocardial Infarction
44
What is the indication for dalteparin?
Unstable angina Pulmonary embolism Deep vein thrombosis DVT prophylaxis
45
What is the indication for dobutamine?
Coronary artery disease, MI Cardiac surgery Septic/cardio shock Cardiomyopathies
46
What is the indication for doxazosin?
Hypertension | Benign prostatic hyperplasia
47
What is the indication for ephedrine?
Reversal of hypotension from anaesthesia Airway obstruction Neuropathic oedema Nasal congestion
48
What is the indication for erythromycin?
Enteric bacteria Strep. Pyogenes H. Influenzae Staph. Aureus
49
What is the indication for ethinylestradiol?
Menstrual disorders F hypogonadism Osteoporosis prophyl. Prostate cancer
50
What is the indication for furosemide?
Hypertension Oedema related to: Heart Failure Renal disease Liver cirrhosis
51
What is the indication for ipratropium?
COPD Asthma Rhinorrhoea
52
What is the indication for loperamide?
Diarrhoea Inflammatory bowel disease IBS
53
What is the indication for metformin?
Diabetes | Polycystic ovary syndrome
54
What is the indication for methotrexate?
Rheumatoid arthritis Crohn's disease Neoplastic diseases Severe psoriasis
55
What is the indication for oxybutinin?
Urinary frequency, urgency & incontinence | Neurogenic bladder dysfunction
56
What is the indication for paracetamol?
Fever | Pain
57
What is the indication for ramipril?
Heart Failure Hypertension MI, Stroke Nephropathy
58
What is the indication for rifampicin?
``` TB Leprosy Legionnaire's H. influenza Meningococcus ```
59
What is the indication for rivaroxiban?
DVT PE Stroke
60
What is the indication for salmeterol?
Asthma | COPD
61
What is the indication for sildenafil?
Erectile dysfunction | Pulmonary hypertension
62
What is the indication for suxamethonium?
General Anaesthesia - Surgery
63
What is the indication for tamsulosin?
Benign prostatic hyperplasia
64
What is the indication for tramadol?
Moderate to severe pain
65
What is the action of alendronate?
Inhibits osteoclast mediated bone resorption by inhibiting the enzyme FPP synthase
66
What is the action of atenolol?
Binds to beta-adrenergic receptors in the heart and vascular smooth muscle, inhibiting sympathetic stimulation
67
What is the action of atracurium?
Binds competitively with cholinergic receptor sites to antagonise acetylcholine action
68
What is the action of bendro-flumethiazide?
Inhibits Cl reabsorption at early distal tubule, results in increase of Na, Cl and water excretion
69
What is the action of cefuroxime?
Inhibition of bacterial cell wall synthesis -> death due to lysis
70
What is the action of celecoxib?
Inhibits Cox-2 cyclooxygenase -> inhibits prostaglandin synthesis
71
What is the action of chlorampenicol?
Bacteriostatic - inhibits protein synthesis by interfering with substrate binding
72
What is the action of ciclosporin?
Decreases lymphocyte function | Binds to cytosolic protein, inhibiting calcineurin -> less inflammatory cytokine production
73
What is the action of ciprofloxacin?
Inhibition of bacterial DNA gyrase enzyme -> prevents DNA replication so stops replication
74
What is the action of co-amoxiclav?
Beta-lactamase inhibitor + inhibits penicillin binding proteins -> inhibits bacterial cell wall synthesis
75
What is the action of diamorphine?
Mu-opioid agonist | Acts on receptors in the CNS which produces an analgesic effect
76
What is the action of dalteprain?
Inhibits the formation of factor Xa and thrombin
77
What is the action of dobutamine?
Directly stimulates Beta-1 receptors in the heart, increases myocardial contractility and stroke volume
78
What is the action of doxazosin?
Inhibits postsynaptic alpha 1 adrenoceptors on vascular smooth muscle - peripheral vasodilation
79
What is the action of ephedrine?
Stimulation of adrenergic receptors | Increases noradrenaline action and release
80
What is the action of erythromycin?
Inhibits bacterial protein synthesis | Bacteriostatic/cidal dependent on dose
81
What is the action of ethinylestradiol?
Interaction with oestrogen receptors in target cells
82
What is the action of furosemide?
Inhibits water reabsorption in the nephron (blocks Na-K-Cl cotransporter)
83
What is the action of ipratropium?
Blocks muscarinic ACh receptors, promoting cGMP degradation - reduces bronchoconstriction
84
What is the action of loperamide?
Acts on mu-opioid receptors in PNS -> slows intestinal motility Doesn't cross the BBB so can't affect CNS
85
What is the action of metformin?
Decreases hepatic glucose production and intestinal glucose absorption Improves insulin sensitivity
86
What is the action of methotrexate?
Cancer - inhibition of DHFR, inhibiting folate synthesis. | Arthritis - inhibition of purine metabolism = accumulation of adenosine = suppression of T cells
87
What is the action of oxybutin?
Antagonist of M1, 2 & 3 muscarinic ACh receptors | Decreases muscle spasms of the bladder
88
What is the action of paracetamol?
COX enzyme inhibition in CNS indirectly
89
What is the action of ramipril?
Inhibit ACE activity Less Angiotensin II produced Less Bradykinin breakdown Relaxation of arterial smooth muscle
90
What is the action of rifampicin?
Inhibits bacterial RNA polymerase enzyme - no RNA synthesis
91
What is the action of rivaroxiban?
Competitive irreversible inhibition of factor Xa. | Prevents thrombin formation
92
What is the action of salmeterol?
Beta 2 stimulation causes relaxation of bronchial smooth muscle
93
What is the action of sildenafil?
Increases cGMP to cause smooth muscle relaxation - vasodilation
94
What is the action of suxamethonium?
Mimics ACh at NM junction, with slow hydrolysis - prolongs depolarisation = NM blockade
95
What is the action of tamsulosin?
Selective A1 antagonist | Causes relaxation in smooth muscle = less resistance to urinary flow=less pain in BPH
96
What is the action of tramadol?
Agonist of mu-opioid receptors Serotonin & norepinephrine reuptake inhibitor Enhances serotonin release

2a Bateman - Phase 2a MASTER DECK (24 decks)

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