Micro Flashcards
What microbes increase from Periodontitis to Health
G+ve Anaerobe cocci
Microbes in the Red Complex
Treponema Denticola
Porphyromonas Gingivalis
Tannerella Forsythia
Treponema Denticola
Spirochete
G-ve Obligate anaerobe
Porphyromonas Gingivalis
G-ve anaerobic rod
Tannerella Forsythia
G-ve Anaerobic (spindle rod?)
Pioneer Plaque Enzyme?
Glycosidase
Break Sialic bonds?
Glycosidase
Glyco Protein enzyme breaks side chains?
Glycosidase
What enzyme breaks down complex carbs attached to acquired pellicle?
Amylase
Initial Metabolism pathogen enzyme for Red Complex =
Enzyme breaks down A.A starter chain?
Exopeptidases
EPS produced by macromolecule?
GTF
GTF produces?
EPS
EPS metabolism?
polysaccharides
1-4a linkage is more?
Hydrophobic
1-6 Linkage is more?
Hydrophillic
Cariogenic plaque?
Low pH, proliferation of acidogenic, aciduric bacteria and decrease urea ammonia production
Early Colonisers?
Gram +ve Cocci
What protease used by initial colonisers to decrease immune defence?
IgA
Equation?
D/H = Dose x Virulence
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Resistance
What does P. gingivalis use to disrupt enzyme control of collagen formation?
Gingipains to Matrix Metalloproteinases
Collagenase to break down Collagen
Secondary colonisers?
G+ve/-ve rod
Late Colonisers?
G-ve rods/motile
Most dominant G+ve rods interproximally in plaque associated gingivitis?
Actinomyces
S. gordonii and s. oralis are apart of which Streptococci group?
Mitis
Veillonella protective against caries because?
metabolise lactate not use ATP
Lysis of what cell type by toxin release iron for p. gingivalis?
Erythrocytes
Pioneers?
S. mitis
S. Sobrinus is a group of which streptococci?
Mutans
Transition from Health to Periodontitis sees increase in what types?
G-ve anaerobic rods
what class of proteins are salivary mucins?
Glycoprotein
