Micro Flashcards

1
Q

What microbes increase from Periodontitis to Health

A

G+ve Anaerobe cocci

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2
Q

Microbes in the Red Complex

A

Treponema Denticola
Porphyromonas Gingivalis
Tannerella Forsythia

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3
Q

Treponema Denticola

A

Spirochete

G-ve Obligate anaerobe

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4
Q

Porphyromonas Gingivalis

A

G-ve anaerobic rod

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5
Q

Tannerella Forsythia

A

G-ve Anaerobic (spindle rod?)

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6
Q

Pioneer Plaque Enzyme?

A

Glycosidase

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7
Q

Break Sialic bonds?

A

Glycosidase

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8
Q

Glyco Protein enzyme breaks side chains?

A

Glycosidase

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9
Q

What enzyme breaks down complex carbs attached to acquired pellicle?

A

Amylase

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10
Q

Initial Metabolism pathogen enzyme for Red Complex =

Enzyme breaks down A.A starter chain?

A

Exopeptidases

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11
Q

EPS produced by macromolecule?

A

GTF

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12
Q

GTF produces?

A

EPS

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13
Q

EPS metabolism?

A

polysaccharides

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14
Q

1-4a linkage is more?

A

Hydrophobic

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15
Q

1-6 Linkage is more?

A

Hydrophillic

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16
Q

Cariogenic plaque?

A

Low pH, proliferation of acidogenic, aciduric bacteria and decrease urea ammonia production

17
Q

Early Colonisers?

A

Gram +ve Cocci

18
Q

What protease used by initial colonisers to decrease immune defence?

A

IgA

19
Q

Equation?

A

D/H = Dose x Virulence
————————–
Resistance

20
Q

What does P. gingivalis use to disrupt enzyme control of collagen formation?

A

Gingipains to Matrix Metalloproteinases

Collagenase to break down Collagen

21
Q

Secondary colonisers?

A

G+ve/-ve rod

22
Q

Late Colonisers?

A

G-ve rods/motile

23
Q

Most dominant G+ve rods interproximally in plaque associated gingivitis?

A

Actinomyces

24
Q

S. gordonii and s. oralis are apart of which Streptococci group?

A

Mitis

25
Q

Veillonella protective against caries because?

A

metabolise lactate not use ATP

26
Q

Lysis of what cell type by toxin release iron for p. gingivalis?

A

Erythrocytes

27
Q

Pioneers?

A

S. mitis

28
Q

S. Sobrinus is a group of which streptococci?

A

Mutans

29
Q

Transition from Health to Periodontitis sees increase in what types?

A

G-ve anaerobic rods

30
Q

what class of proteins are salivary mucins?

A

Glycoprotein