MI Flashcards

1
Q

Treatment of MI

A
diMorphine + anti-emetic
Oxygen - high flow
Nitroglycerin (GTN)
Aspirin - 300mg
Clopidogrel - 300mg
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2
Q

when should patients be treated with PCI

A

within 90 mins

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3
Q

what should happen is PCI can’t be done within 90 mins

A

fibrinolytic therapy within 30 min

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4
Q

what are contraindications of thromboylsis

A

recent surgery/trauma/head injury
peptic ulcer
recent stroke

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5
Q

examples of anti-emetics

A

metoclopramide

cyclizine

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6
Q

what are complications of MI

A
Arrhythmias
Ventricular Septal Perforation
Ventricular Free Wall Rupture
Systemic Embolism 
Ventricular Aneurysm
Pericarditis
Cardiogenic Shock
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7
Q

if a patient was hypotensive what drug would you not give

A

nitrates

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8
Q

what should patients be offered after an MI (drugs)

A
ACEi
Aspirin
Beta blocker
Statin
Aspirin and Clopidogrel
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9
Q

if a patient has signs of HF what should they be offered

A

aldosterone antagonists e.g. spironolactone

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10
Q

what is the features of chronic angina

A

fixed stenosis
demand led ischaemia
predictable

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11
Q

what is the features of acute coronary syndrome

A

dynamic stenosis
supply led ischaemia
unpredictable

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12
Q

what are the steps of the platelet cascade

A
1 - initiation
2 - adhesion
3 - activation
4 - release of activators (e.g. ADP, TA2)
5 - activators bind to receptors
6 - amplification of platelet activation
7 - triggers inflammatory cascade
8 - organised thrombus
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13
Q

what is the classic features of an MI

A

Severe crushing central chest pain
Radiating to jaw and arms, especially the left
Not relieved by GTN
Associated with sweating, nausea, vomiting

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14
Q

what are the signs of STEMI that must be on an ECG

A

> 1mm ST elevation in 2 adjacent limb leads
OR
2mm ST elevation in at least 2 precordial leads that are next to each other

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15
Q

what are arrhythmic complications of an MI

A

Ventricular fibrillation

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16
Q

what are structural complications of an MI

A
Cardiac rupture
Ventricular septal defect
Mitral valve regurgitation
Left ventricular aneurysm formation - blood clot in the LV. 
Mural thrombus +/- systemic emboli
Inflammation
Acute pericarditis
Dressler's syndrome
17
Q

what happens in a ventricular septal defect

A

infarct the septum, pressure from LV causes hole and blood flows into RV.
Can cause acute HF.

18
Q

what are functional complications of an MI

A

Acute ventricular failure
Chronic cardiac failure
Cardiogenic shock

19
Q

what is TnT also raised in bar a MI

A
CCF
Hypertensive crisis
Renal failure
Pulmonary embolism
Sepsis
Stroke/TIA
Pericaditis / Myocarditis
Post arrhythmia
20
Q

what is the final pathway to platelet aggregation

A

GP IIb-IIIa