Hypertension Flashcards

1
Q

what is hypertension risk factor for

A

cerebral haemorrhage
atheroma
renal failure
sudden cardiac death

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2
Q

what are the renal causes of hypertension

A
renal artery stenosis 
acute/chronic glomerulonephritis 
chronic pyelonephritis
cystic diseases
interstitial nephritis
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3
Q

what are endocrine causes of hypertension

A

pheochromocytoma - excess noradrenaline

adrenal gland hyperfunction/tumours

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4
Q

what are congenital causes of hypertension

A

coarctation of the aorta

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5
Q

what drugs induce hypertension

A

corticosteroids

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6
Q

what does benign hypertension go on to cause

A
Left ventricular hypertrophy				
Congestive cardiac failure				 
Increases atheroma					 
Increases aneurysm rupture - aortic dissection, Berry aneurysms
Renal disease
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7
Q

what is the pathology of LVH

A
Increased LV load
Poor perfusion
Interstitial fibrosis
Micro-infarcts
Diastolic dysfunction
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8
Q

what can LVH cause

A

Sudden cardiac death
Arrhythmia and poor perfusion
Cardiac failure
Affects outcomes of other disease

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9
Q

what does malignant hypertension cause

A

Causes cerebral oedema - seen as papilloedema (swelling of optic disc)
Acute renal failure
Acute heart failure
Headache and cerebral haemorrhage

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10
Q

how do the blood vessels appear in malignant hypertension

A

Blood vessels show fibrinoid necrosis and endarteritis proliferans of their walls

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11
Q

what are early signs of pre-exlampsia

A

hypertension

proteinuria

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12
Q

what are signs of end organ damage in hypertension

A

Left Ventricular Hypertrophy
Creatinine Raised
Albuminuria / microalbuminuria
Retinopathy

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13
Q

what is the target BP in those under 80 - clinical and ABPM/HBPM

A

140/90 mmHg

135/85 mmHg

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14
Q

what is the target BP in those 80 and over - clinical and ABPM/HBPM

A

150/90 mmHg

145/85 mmHg

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15
Q

clinical signs of Conn’s sydrome

A

Primary aldosteronism
Severe hypertension
Severe hypokalemia

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16
Q

how would primary aldosteronism be diagnosed

A

Adrenal CT scan

17
Q

what is the ratio of decreased hypertension to weight loss

A

1mmHg for every kg

18
Q

is it better to add or titrate drugs

A

Adding a drug

19
Q

what are measures to test concordance in hypertensive drugs

A

Plasma ACE: ACEIs
Response: BP, pulse (β-blockers)
Plasma drug levels
Tracer doses

20
Q

what is the rules for use of spironolactone

A

start low - go slow

caution in diabetes and low Glomerular filtration rate (GFR)

21
Q

what is Glomerular filtration rate (GFR)

A

a measure of how well the kidneys are working