MHC and TCRs/BCRs in antigen recognition Flashcards

1
Q

Understand importance of polymorphism, polygeny and co-dominance.

A

93

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2
Q

Know what heterozygote advantage is and its affect on disease

A

93

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3
Q

Understand the different functions of MHC class I and class II

A

a

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4
Q

Understand the differences in peptides that are presented in MHC I and MHC II

A

a

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5
Q

Know the cells that present MHC I and MHC II

A

a

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6
Q

Know the cells that are activated by MHC I and MHC II

A

a

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7
Q

Understand the function of genes in MHC class III

A

94

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8
Q

Understand MHC restriction

A

a

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9
Q

Know the definition of superantigen

A

a

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10
Q

Know the structure of the TCR complex

A

a

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11
Q

Understand co-receptors.

A

a

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12
Q

Know the molecules involved in adherence and interactions

A

a

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13
Q

Understand “first signal” and “second signal”

A

a

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14
Q

Understand what signals result in tolerance

A

a

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15
Q

Understand Th1 vs Th2 with important cytokines

A

98

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16
Q

Understand differences of alpha-beta and gamma-delta TCR

A

95

17
Q

Know where the change from Pre-B cell to naive B cell takes place

A

a

18
Q

Know where activation of immature B cells takes place

A

a

19
Q

What happens to the B cell when it is activated?

A

a

20
Q

Understand mature B cells/plasma cells

A

a

21
Q

What structures combine to make a functional BCR?

A

a

22
Q

What molecules and particular domains are responsible for signaling to the nucleus?

A

a

23
Q

Know alternate methods of antigen recognition by the B cell

A

a

24
Q

Understand processing of antigen in the B cell

A

a

25
Q

Understand the first and second signal and necessary molecules for activation of a T cell

A

a

26
Q

Understand cross-linking of BCR

A

a

27
Q

What is the difference between partial activation and full activation?

A

a

28
Q

What is the importance of CD40-CD40 ligand interaction?

A

a