Metabolism and Control of Body Weight Flashcards
Role of metabolism
Energy producing
Synthesising and degrading
Rid of waste products
What is the metabolic rate
The energy required to maintain normal physiologucal function under conditions of minimal mechanical effort
what happens to energy expenditure in disease
it decreases
resp exchange ratio
rate of C02 production / rate of 02 consumption
Where is the central regulation of food intake located
Hypothalamus
What is the lateral nuclei responsible for
Main feeding centre - increase desire in food
What is the ventromedial nuclei responsible for
Satiety centre - inhibits feeding centre
What does proopiomelanocortin neurons do
Decrease intake and secrete alpha melanocyte stimulating hormones
What does orexigenic neurons do
Increase intake and release neuropeptide gamma
what will a decrease in glucose and FFA lead to
increase in food intake
What will an increase in CCK and GLP-1 lead to
Decrease in food intake
Where does short term regulation of food intake come from
Nutrient - related signals
Where does long term regulation food intake come from
Sensing of energy stores
What does an increase in leptin and insulin cause
decrease in food intake
What will over feeding lead to
+ve energy balance
