Endocrine control of calcium metabolism Flashcards
What are the regulators of the parathyroid hormone
Low Ca
high phosphate
what are the actions of the PTH in the bone
short term - rapid exchange
long term - resorption
What are the actions of PTH in the kidney
Reabsorption of Ca2+
Excretion of PO4 3-
formation of vit d
What are the actions of the GI in the bone
Ca2+ absorption
Relationship between Ca2+ and PTH
Low levels of Ca2+ and high levels of PTH
negative feedback
Causes of hypocalcaemia
hypoparathyroidism - removal/injury of parathyroid glands
Pseudohypoparathyroidism- cells unresponsive
Vit D deficiency
Clinical signs of hypocalcaemia
neuromuscular hyperexicitability
Calcium stabilies RMP - threshhold reached more easily
Causes of hyperparathyroidism
Increase in serum Ca2+
all forms of hyperparathyroidism