METABOLIC DISORDER (L) Flashcards
disturbance of carbohydrate metabolism caused by
lack of insulin
a. diabetes mellitus
b. cushing’s syndrome
c. addison’s disease
d. none of the above
A
the following are classic symptoms of Hurler’s syndrome, except
a. hepatosplenomegaly
b. alpecia
c. corneal clouding
d. protuberant belly
B
hypopituitarism is caused by the compression or
atrophy of anterior pituitary cells or defect in the hypothalamic control of hormonal secretion
a. true
b. false
B
the following are clinical features of hypoparathyroidism, except:
a. tetany
b. muscle spasm
c. muscle stiffness
d. muscle atrophy
D
the following are causes of hypoparathyroidism, except:
a. surgical removal
b. disease of the glands
c. congenitally absent glands
d. all of the above
D
adrenal gland regulate the following hormones, except:
a. cortisol
b. glucocorticoids
c. sex hormones
d. insulin
D
the following are other names of Hurler’s syndrome, except:
a. MPS IH
b. Progeria
c. Gargoylism
d. Mucopolysaccharidosis
B
Develops in children whose diet id deficient in proteins.
a. Niemann-Pick disease
b. Kwashiorkor
c. Leterrer-Siwe disease
d. Marasmus
B
Langerhans cells comes with eosinophils, sometimes with other types of granulocytes
a. True
b. False
A
Less common, chronic, non-neurological form of Niemann-pick disease with presence of niemann-pick cells upon histological examination
a. Type a
b. Type c
c. Type b
d. Type d
C
The following are cinical features of progeria, except
a. Kypphoscoliosis
b. Atrophic skin
c. Exophthalmos
d. Break like nose
A
In addison’s disease, melanotic macules are absent on oral mucosal surfaces.
a. True
b. False
B
rare inherited disorder of the connective tissue characterized by a defect in collagen metabolism
a. Cushing’s syndrome
b. Addison’s disease
c. Acromegaly
d. Ehlers-danlos syndrome
D
Hypothyroidism with an infancy onset
a. Cretinism
B. Myxedema
c. Juvenile myxedema
d. Cushing’s syndrome
A
chromosomal abnormality that involves disturbance of mucopolysaccharide metabolism characterized by an elevated mucopolysaccharide excretion level in the urine.
a. Hand schuller Christian disease
b. Marasmus
c. Niemann-pick disease
d. Huler’s syndrome
D
rare disease of unknown etiology is characterized by dwarfism and premature senility.
a. Progeria
b. Huerler’s syndrome
c. Eosinophilic granuloma
d. Niemann pick disease
A
following are clinical features of hyperpituitarism, except:
a. Class III malocclusion
b. Macrognathia
c. Micrognathia
d. Hypercementosis
C
In progeria, baldness and a characteristic of “plucked bird appearance” generally developed by age 10.
a. True
b. False
B
Characterized metabolically by a decreased excretion of parathormone leading to increased neuromuscular excitability
a. Hypoparathyroidism
b. Hypopituitarism
c. Hypoadrenalism
d. Hypothyroisism
A
In leterrer siwe disease, no presence of foam cells and fibrosis are found histologically
a. True
b. False
A
Chronic multifocal form of langer hans cell histiocytosis that occurs on young adults and teens
a. Leterrer siwe disease
b. Hand schuller Christian disease
c. Eosinophilic granuloma
d. Niemann-pick disease
B
An autosomal-recessive trait manifested by hypoglycemia and vomiting after the ingestion of fructose- containing food
a. Hutchinson gillford syndrome
b. Hand schuller Christian disease
c. Niemann-pick disease
d. Hereditary fructose intolerance
D
An acute infantile and severe form of niemann-pick disease with extensive neurologic involvement
a. Type a
b. Type b
c. Type c
d. Type d
A
The following are classic features of ehlers-danlos
syndrome, except
a. Joint hypermobility
b. Skeletal deformities
c. Skin rigidity
d. Kyphoscoliosis
C
Hyperpituitarism in which the abnormal increase in growth hormone outputs occurs before the epiphyses
of the long bones are called
a. Acromegaly
b. Gigantism
c. Hirsuitism
d. None of the above
b
The following are the hand-schuller triad, except
a. Exophthalmos
b. Diabetes mellitus
c. Lytic skull lesions
d. Hyperthyroidism
D
Hypothyroidism with an adult onset.
a. Gigantism
b. Juvenile myxedema
c. Cretinism
d. Myxedema
D
In eosinophilic granuloma oral lesions are centered in the palatal area
a. True
b. False
B
Hereditary fructose intolerance is results from a deficiency in fructose 2-phosphate aldolase
a. True
b. False
B
Gigantism and acromegaly are classic features of this metabolism disorders
a. Hyperpituitarism
b. Hypopituitarism
c. Hyperthyroidism
d. Hypothyroidism
A
Histologic feature of gargoyle cells can be agranular or
finely granular with a crescent shaped nuclei
a. True
b. false
A
Hyperpituitarism in which the abnormal increase in
growth hormone output occurs after the epiphyses of the long bones are closed
a. Gigantism
b. Acromegaly
c. Hirsutism
d. None of the abpve
B
A form of hyperthyroidism characterized by diffuse
hyperplasia of the thyroid and prominent ocular changes.
a. Toxic goiter
b. Exopthlamic goiter
c. Acromegaly
d. Cushing’s syndrome
B
A form of hyperthyroidism in which hyperfunction
originates in a benign tumor of the thyroid gland
a. Toxic goiter
b. Hypertelorism
c. Exophthalmic goiter
d. Cushing’s syndrome
A
Insulin dependent diabetes mellitus is also known as juvenile onset diabetes
a. True
b. False
A
Ehlers-danlos syndrome is a defect in formation and structure of___
a. None of the above
b. Type III collagen
c. Type I
d. Type II
B
The following are clinical features of cushing’s syndrome, except:
a. Hirsutism
b. Buffalo hump
c. Exophthalmos
d. Mooning of the face
C
A form of hyperparathyroidism that occurs in end- stage renal disease
a. Primary hyperparathyroidism
b. Secondary hyperparathyroidism
c. Hypoparathyroidism
d. None of the above
B
Hypothyroidism in children is called___
a. Myxedema
b. Cushing’s syndrome
c. Juvenila myxedema
d. Cretinism
C
Excessive accumulation of intracellular mucopolysaccharide in tissues and organs in patients diagnosed with hurler’s syndrome
a. Gaucher cells
b. Gargoyle cells
c. Langerhans cells
d. Nieman pick foam cells
B
Disturbance in protein metabolism caused by simple starvation
a. Marasmus
b. Niemann-pick disease
c. Kwashiorkor
d. Hurler’s syndrome
A
A chronic unifocal form of Langerhans cell histiocytosis that involves the skeletal and lymphatic system
a. Gargoylism
b. Hand schuller disease
c. Eosinophilic granuloma
d. Leterrer siwe disease
C
The sum total of tissue activity in terms of physico- chemical changes associated with the utilizationand disposal of protein fat, carbohydrate, vitamins, minerals, water, and the influences which the endocrines exert on these processes.
a. Anabolism
b. Metabolism
c. Digestion
d. Catabolism
B
On all three non-lipid metabolism disorders, hand schuller disease has extremely poor disease outcome with a 5-year survival rate.
a. True
b. False
B
Proliferation of immune system cells normally found in the body derived from the bone marrow and migrate to function within epithelium
a. Niemann pick disease
b. Langerhans cell histocytosis
c. Gaucher’s disease
d. Hurler’s syndrome
B
A form of niemann-pick disease characterized with intercellular cholesterol esterification
a. Type a
b. Type b
c. Type c
d. Type d
C
Patients with progeria have a life span of up to 30-40 years of age
a. True
b. False
B
An acute disseminated form of Langerhans cell histocytosis characterized by multi-organ involvement
a. Letterer- siwe disease
b. Hand-schuller Christian disease
c. Eosinophilic granuloma
d. None of the above
A
Generalized bronzing of the skin is a prominent feature of
a. Hyperthyroidism
b. Hyperparathyroidism
c. Addison’s disease
d. Diabetes mellitus
C
Develops following the autoimmune destruction of adrenal glands and occurs in conjunction with other autoimmune disorders.
a. Hypothyroidism
b. Diabeter mellitus
c. Ehlers-danlos syndrome
d. None of the above
D
