Metabolic bone disease Flashcards
1
Q
what is osteoporosis
A
low bone mass
micro-architectural deterioration
2
Q
common # sites in osteoporosis
A
hip, spine, wrist
3
Q
drugs that cause osteoporosis
A
steroids
aromatase inhibitors (reduce oestrogen in BrCa Rx)
depo-provera
4
Q
which # in FHx is particularly predicting of #
A
parent NOF#
you can also ask if parent had kyphosis but this is less strong
5
Q
sx vertebral #
A
height loss, back pain
6
Q
social hx RF osteoporosis
A
smoking and alc!!!
7
Q
when to request DXA
A
low trauma # meds assoicated with osteoporosis osteopenia on xray (usually incidental) disease associated with osteoporosis menopause <45y or amenorrhoea FH, low BMI rate of change
8
Q
diseases associated with osteoporosis
A
RA thyrotoxicosis malabsorption renal failure hypogonadism primary hyperparathyroidism diseases eating disorders
can ix for these in OP
9
Q
names of two bisphosphoantes
A
alendronic acid
zolendronic acid
10
Q
monoclonal antibody to treat osteoporosis
A
denosumab
11
Q
what to give in osteop along with bisphosphonates
A
calcium and vit d
