Merritt's 13th

Question 1

CT perfusion findings of the penumbra
A. Decreased cerebral blood flow, decreased mean transit time, decreased cerebral blood volume
B. Decreased cerebral blood flow, increased mean transit time, decreased cerebral blood volume
C. Decreased cerebral blood flow, increased mean transit time, increased cerebral blood volume
D. Increased cerebral blood flow, increased mean transit time, increased cerebral blood volume

Answer 1

C. Decreased cerebral blood flow, increased mean transit time, increased cerebral blood volume (pp. 274-275)

Question 2

CT perfusion findings of the ischemic core
A. Decreased cerebral blood flow, decreased mean transit time, decreased cerebral blood volume
B. Decreased cerebral blood flow, increased mean transit time, decreased cerebral blood volume
C. Decreased cerebral blood flow, increased mean transit time, increased cerebral blood volume
D. Increased cerebral blood flow, increased mean transit time, increased cerebral blood volume

Answer 2

B. Decreased cerebral blood flow, increased mean transit time, decreased cerebral blood volume (p. 275)

Question 3

This study provided the basis for the 3-hour time period of giving IV tPA
A. NINDS
B. ECASS II
C. ECASS III
D. PROACT II

Answer 3

A. NINDS (p. 276)

Question 4

This study's inclusion criteria provided the basis for the contraindications in giving tPA
A. NINDS
B. ECASS II
C. ECASS III
D. PROACT II

Answer 4

A. NINDS (p. 277)

Question 5

This study provided the basis for extending the window period of giving IV tPA to 4.5 hours in a select group of patients
A. NINDS
B. ECASS II
C. ECASS III
D. PROACT II

Answer 5

C. ECASS III (p. 276)

Question 6

In this study, 180 patients with proximal MCA occlusion within 6 hours of symptom onset were randomized into IA proukinase + IV heparin vs IV heparin alone
A. NINDS
B. ECASS II
C. ECASS III
D. PROACT II

Answer 6

D. PROACT II (p. 278)

Question 7

This study showed no benefit in functional outcomes at 3 months for tPA plus adjunctive endovascular therapy administered within 5 hours of stroke onset compared to tPA administration alone
A. ECASS II
B. ECASS III
C. PROACT II
D. IMS III
E. SYNTHESIS
F. MR-RESCUE

Answer 7

D. IMS III (p. 278)

Question 8

The results of this study showed that good functional recovery at 3 months was seen in 35% of the IV tPA group compared to 30% in the endovascular group
A. ECASS II
B. ECASS III
C. PROACT II
D. IMS III
E. SYNTHESIS
F. MR-RESCUE

Answer 8

E. SYNTHESIS (p. 278)

Question 9

This study failed to show benefit of endovascular intervention compared to IV tPA in patients with perfusion deficits determined by MR or CTP imaging
A. ECASS II
B. ECASS III
C. PROACT II
D. IMS III
E. SYNTHESIS
F. MR-RESCUE

Answer 9

F. MR-RESCUE (p. 278)

Question 10

In this study, the proportion of patients with minimal or no disability at 90 days was 33% in those treated with IAT and tPA compared to tPA alone but had no effect on mortality.
A. MR CLEAN
B. EXTEND IA
C. ESCAPE
D. REVASCAT
E. SWIFT PRIME
F. THRACE
G. THERAPY

Answer 10

A. MR CLEAN (p. 278)

Question 11

This study included patients older than age 60 and showed mortality reduction from 70% to 33% among patients who underwent hemicraniectomy, but with worsened neurologic outcomes compared to younger patients
A. DECIMAL
B. DESTINY
C. DESTINY II
D. HAMLET

Answer 11

C. DESTINY II (p. 280)

Question 12

Reversal of NOAC-associated ICH includes the following EXCEPT*
A. Hemodialysis
B. FEIBA
C. PCCs
D. rFVIIa
E. All of the above can be used

Answer 12

E. All of the above can be used (p. 298)