Greenfield's 9th

Question 1

How are foam cells formed in atherosclerosis?
A. Macrophages uptake lipids
B. Monocytes mature in the endothelium
C. Extracellular lipid derived from dead cells accumulates in the central region of the plaque
D. Smooth muscle cells migrate from the media to the intima

Answer 1

A. Macrophages uptake lipids (p. 93, Fig 2.26)

Question 2

NOT true of Takayasu’s arteritis*
A. The inflammation affects primarily the tunica media, causing destruction of the elastic lamellae and inducing the formation of foreign body giant cells.
B. Secondary fibrosis of all layers causes thickening and loss of compliance of the blood vessel walls, resulting in characteristic loss of carotid pulsations.
C. The arteritis may result in cerebral ischemia, usually because of embolism.
D. The vertebral arteries are not affected.

Answer 2

D. The vertebral arteries are not affected. (p. 102)