Mental Health Flashcards

1
Q

what are 3 postpartum psychiatric conditions

A
  1. postpartum blues
  2. postpartum depression (symptoms for at least 1 month)
  3. postpartum psychosis (begins within 4 weeks)
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2
Q

are antidepressants teratogenic?

A

No!!

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3
Q
what are some consequences of maternal depression
infant
toddler
school aged
adolescent
A

infant- anger
lower cognitive performance

toddler- Less creative play and lower cognitive performance
poor self control, lower interaction, passive noncompliance

school aged- Internalizing and externalizing problems, impaired adaptive functioning, anxiety, conduct disorders
ADHD, lower IQ

adolescent- depression, anxiety, panic disorders, conduct disorders, substance use
ADHD, learning disabilities

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4
Q

what screening questions would you ask to assess for cardiac risk factors for sudden death among children starting stimulant medication

A

Personal History:
SOB with exercise without explanation (asthma)
Poor exercise tolerance without other explanation
Fainting/Seizures with exercise, or fright
Palpitations with exercise

Personal or Fam Hx of:
sudden death
FamHx non-ischemic heart disease
FamHx/Personal Hx Long QT or arrythmia
WPW
Cardiomyopathy 
Heart transplant
Pulm HTN
Defibrillator

Exam:
Hypertension
Murmur
Sternotomy incision

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5
Q

what is one of the strongest predictors of suicide during adolescence, and lifelong

A

A previous suicide attempt is one of the strongest predictors of suicide during adolescence, and lifelong

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6
Q

what risk factors are associated with increased risk of suicide?

A
Mental illness
Prior self-harm or suicide attempt
Impulsivity
Precipitating factors
Family factors (family conflict)
Lack of psychosocial support
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7
Q

what should you ask on history to screen for risk of sudden cardiac death prior to starting stimulant medication

A

SOB on exercise without explanation
exercise intolerance
palpitations brought on by exercise
fainting/seizures with exercise

FHx of personal hx of:
long QT, arrhythmias
nonischemic heart disease
WPW
Cardiomyopathy
Pulmonary HTN
Heart transplant
sudden unexplained death
unexplained MVAs or drownings
Defibillator
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8
Q

what should you look for on physical exam to screen for risk of sudden cardiac death prior to starting stimulant medication (3)

A

sternotomy scar
HTN
organic murmur
other abnormal cardiac findings

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9
Q

effects of divorce for age:
<3
4-5
school age

A

less than 3: may reflect a caregiver’s distress and grief
age 4-5: blame themselves and become clingy with separation anxiety
School age: may take sides and have loyalty conflicts

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10
Q

family protective factors for divorce (8)

A
Protection from conflict between parents
Cooperative parenting
Healthy relationships between child and parents
Parents’ psychological well being
Quality, authoritative parenting
Household structure and stability
Supportive sibling relationships and extended family relationships
Economic stability
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11
Q

family risk factors for divorce (8)

A
Ongoing conflict between parents
Poor parenting
Lack of monitoring children’s activities
Multiple family transitions
Parent mental health problems
Chaotic, unstable household
Impaired parent-child relationships
Economic decline
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12
Q

what are the 3 main processes that have a positive mediating effect on child well-being after parental divorce

A

improving the quality of parenting

improving the quality of parent–child relationships controlling hostile conflict

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13
Q

are routine labs required before starting an SSRI?

A

No routine Labs needed prior to starting (unless screening for thyroid as cause of sx, liver disease if concerning symptoms, or monitoring other drug levels that may interact, like valproic acid

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14
Q

After starting an SSRI in a child what monitoring is required?

A

1) weekly for the first four weeks after initiation of SSRI
2) every two weeks for the next four weeks;
3) at 12 weeks;
4) as clinically indicated beyond the 12-week point

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15
Q

Once a complete response has been achieved with SSRI, how long should the medication be continued?

A

should be continued for a minimum of six to 12 months to decrease the risk of depressive relapse

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16
Q

Which SSRI medication has the most data supporting its use for treating depression in children and adolescents?

A

Fluoxetine

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17
Q

What is the max dose for citalopram

A

Citalopram should not be used in dosages >40 mg/day.

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18
Q

what children should not be prescribed citalopram

A

should not be prescribed for children and adolescents with congenital long QT syndrome.

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19
Q

what could you tell parents about the risk of SI with starting an SSRI

A

The risk of suicidality associated with untreated depression is likely greater than that associated with appropriate SSRI use.

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20
Q

To improve tolerability of medication for anxious patients, clinicians should include the following in their overall approach: (3)

A

To improve tolerability of medication for anxious patients, clinicians should include the following in their overall approach:
Psychoeducation
Lower starting dosages
Gradual titration to therapeutic dosages.

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21
Q

what is the half life and dosing schedule for fluoxetine

A

96h, dosed daily

22
Q

what are some common short term side effects of SSRI’s

A
gastrointestinal symptoms
sleep changes (either insomnia or somnolence, and sleep disturbances, including vivid dreams)
restlessness
headaches
appetite changes
sexual dysfunction
23
Q

A cluster of disruptive behaviours is considered to be at the disorder level when the following criteria are met:

A

Behaviours are atypical for the child’s developmental age and persist for 6 months or more,
Behaviours occur across situations, and result in impaired functioning, and/or
Behaviours cause significant distress for both child and family

24
Q

what are 3 factors associated with atypical child tantrums

A
  1. frequency (daily or repeated clusters)
  2. intensity (associated with aggressive behaviours)
  3. duration (eg >5min)
25
Q

What is the first-line intervention for children with significant disruptive behaviours?

A

Consider evidence-based parent-training programs as a first-line intervention for children with significant disruptive behaviours.

26
Q

what is the diagnostic criteria for global developmental delay (Table)

A
Significant delay (at least 2 SDs below the mean with standardized tests) in at least two developmental domains from the following: 
Gross or fine motor 
Speech/language 
Cognition 
Social/personal 
Activities of daily living 
Reserved for children <5 years old
27
Q

what are the diagnostic criteria for intellectual disability

A

Intellectual disability (intellectual developmental disorder)*:

The following three criteria must be met:

Deficits in intellectual functions, such as reasoning, problem-solving, planning, abstract thinking, judgment, academic learning and learning from experience, confirmed by both clinical assessment and individualized, standardized intelligence testing.

Deficits in adaptive functioning that result in failure to meet developmental and socio-cultural standards for personal independence and social responsibility. Without ongoing support, the adaptive deficits limit functioning in one or more activities of daily life, such as communication, social participation and independent living, across multiple environments, such as home, school, work and community.

Onset of intellectual and adaptive deficits during the developmental period.

28
Q

what are the 4 broad categories for causes of global developmental delay

A

prenatal intrinsic- genetic, metabolic
prenatal extrinsic- toxins/teratogens, infections
perinatal- asphyxia, prematurity
postnatal- neglect, infections, toxins, trauma

55% from perinatal

29
Q

what are the initial investigations for GDD

A
  1. History and physical
  2. Audiology
  3. Ophthalmology
  4. EEG if seizures
  5. refer to rehabilitation services while awaiting results
30
Q

If GDD is suspected after history/physical and no known cause then what investigations should be done

A
  1. chromosomal microarray
  2. Fragile x- testing
  3. Tier 1 testing
  4. Brain MRI if abnormal neurological exam, seizures, macrocephaly or microcephaly
  5. Consider MECP2 in girls with Mod-Severe GDD
31
Q

If a diagnosis of GDD is not found after microarray and fragile x testing what is the next step

A
  1. Brain MRI
  2. Genetics/Metabolics referral- Tier 2 testing, gene panels
  3. Consider referral to neurology
32
Q

what are the Tier 1 investigations for GDD

A

Complete blood count
Glucose
Blood gas
Urea, creatinine
Electrolytes (to calculate anion gap)
AST, ALT
TSH
Creatine kinase
Ammonia
Lactate
Amino acids
Acylcarnitine profile, carnitine (free and total)
Homocysteine
Copper, ceruloplasmin** - not by recommended AAP but in TIDE protocol
Biotinidase*** - clinica expert recommendation only
Ferritin, vitamin B12 when dietary restriction or pica are present
Lead level when risk factors for exposure are present

33
Q

what are first-line investigations for children with unexplained GDD/ID.

A

Chromosomal microarray and Fragile X DNA testing

34
Q

what are some red flags suggestive of inborn errors of metabolism (table)

A

Family history of IEM or developmental disorder or unexplained neonatal or sudden infant death
Consanguinity
Intrauterine growth retardation
Failure to thrive
Head circumference or stature growth abnormality (>2 SD above or under the mean)
Recurrent episodes of vomiting, ataxia, seizures, lethargy, coma
History of being severely symptomatic and needing longer to recover with benign illnesses (e.g., upper respiratory tract infection)
Unusual dietary preferences (e.g., protein or carbohydrate aversion)
Regression in developmental milestones
Behavioural or psychiatric problems (e.g., psychosis at a young age)
Movement disorder (e.g., dystonia)
Facial dysmorphism (e.g., coarse facial features)
Organomegaly
Severe hypotonia
Congenital nonfacial anomalies
Sensory deficits, especially if progressive (e.g., cataracts, retinopathy)
Noncongenital progressive spine deformities
Neuro-imaging abnormalities

35
Q

what % of children with ADHD will continue to have symptoms in adulthood

A

50%

36
Q

what conditions are often co-morbid with ADHD (similar list for conditions misdiagnosed as ADHD)

A
ODD and CD- as high as 90% with ADHD
Anxiety- 30%
Mood disorder- depressive symptoms, bipolar disorder
substance use disorder
Tic disorder
Developmental coordination disorder (DCD)
ASD
Specific learning disorder
Eating disorders (Especially females)
37
Q

what are the 3 types of ADHD

A
predominantly inattention presentation
predominantly hyperactive-implusive presentation
combined type (criteria are met for inattention and hyperactive)
38
Q

symptoms for ADHD must present before what age and persist for how long

A

before age 12 and persist >6 months

39
Q

what are the criteria for ADHD hyperactivity

A
fidgets
leaves seat
runs/climbs
no quiet play
on the go/motor
talks excessively
blurts
not wait turn
interrupts/intrudes
40
Q

what are the criteria for ADHD inattention

A
close attention/mistakes
sustaining attention
not listen
not follow through
poor organization
sustained mental effort
lose things
easily distracted
forgetful
41
Q

what is ADHD

A

Persistent pattern of hyperactivity-impulsivity and/or inattention that interferes with functioning or development and negatively impacts social/academic/occupation

42
Q

what is the first line treatment for children < 6 yoa with ADHD

A

Parent Behaviour Training

43
Q

what is first line treatment for ADHD >6 yo

A
extended release stimulant
either methylphenidate class or amphetamine class
44
Q

what can happen if you stop Intuniv suddenly

A

rebound hypertension and tachycardia

45
Q

what are 2 non-stimulant treatments for ADHD

A

Straterra (Atomoxetine)-norepinephrine reuptake inhibitor

Intuniv (Guanfacine XR)- alpha 2 agonist

46
Q

what are the non pharmacological interventions for ADHD

*table!!

A
psychoeducation
shared decision making
parent behavior training
classroom management
daily report card
behaviour peer interventions
diet
exercise

others: social skills training, organizational skills training, cognitive training, EEG neurofeedback

47
Q

what are 3 groups that are at increased risk of ADHD

A

ID
prematurity
ASD

48
Q

what are risk factors for persistence of ADHD into adulthood

A

combined inattention/hyperactivity
increased symptom severity
comorbid major depressive or other mood disorder
high comorbidity (>3 additional DSM disorders)
parental anxiety
parental antisocial personality disorder

49
Q

what is the most common adverse effect of stimulations medications in patients with ADHD and Autism

A

irritability and emotional outbursts

50
Q

an IQ above what level predicts a better response to stimulants

A

an IQ above 50 predicts a better response to stimulants

51
Q

what is ‘preterm behavioural phenotype’

A

difficult-to-manage behaviours relate to symptoms associated with ADHD: inattention, internalizing disorders (anxiety, depression, withdrawal, somatic complaints), and social difficulties

Disruptive behaviour disorders, such as oppositional defiant disorder, conduct disorder, and hyperactive/impulsive presentation in ADHD, are seen less frequently