Mental Health Flashcards
Types of depressive disorder
Major: >= 5 symptoms
Minor: 2-4 symptoms
Persistent: 2 years of symptoms
Epidemiology and depression
Leading cause of disability and premature death in 18-44o
2:1 F:M ratio
20% of adults will require medical intervention at some point in their life
2-3x more likely to become depressed if a first degree relative has it
First onset most common in 18-24yo and >65
Pathophysiology of depression
Abdnormal levels of neurotransmitter + dysregulation of HPA + abnormalities of secondary messengers
Methods for screening depression
PHQ-2 which may lead to PHQ-9
Risk factors for depression
Aged >65 Postnatal Female Coritcosteroid use Propranolol use 1st degree relative affected Poor lifestyle Oral contraception Co-existing medical conditions which may make you sad
Clinical presentation of someone with depression
Low mood Weight change Libido change Anhedonia Functional impairment Sleep disturbance Low energy Excessive guilt Suicidal thoughts
Investigations to consider in depression
Bloods: TFTs, FBC, U+E
PHQ2/9 + other questionnaires
Management of depression
If severe: hospitalise + refer + 2nd or 3rd get antidepressants i.e. SSRIs or SNRIs
Definition of general anxiety disorder
> =6 months of excessive worry about everyday issues that are disproportionate to any inherent risk
Symptoms for anxiety disorder
Excessive worry Muscle tension Sleep disturbance Fatigue Restlessness Poor concentration Irritability Anxiety not confined to any other condition or substance
Investigations to consider in anxiety
Usually made from clinical picture
TFTs
FBC
Urine drug screen
Management of anxiety disorder
1st: Pharmacotherapy w/ SSRI / SNRI or tricyclic if others are CI
2nd: CBT
3rd: Augmented treatments
What is alcohol use disorder
Chronic relapsing condition resulting from multifactorial components, characterised by increased tolerance to the effects of alcohol and impaired control over consumption
Epidemiology of alcohol use disorder
Common
7-12% prev. in west
M:F 2:1
3.2% of global deaths due to alcoholism
Pathophysiology of alcohol use disorder
Increased use of alcohol sensitises dopaminergic pathway = dependance
Long term exposure increases excitatory receptors and noradrenaline activity
Withdrawal of alcohol leaves excitatory receptors unposed = symptoms of withdrawal
Risk factors for alcohol use disorder
\+ve FHx Anxiety Lack of facial flushing on consumption of alcohol Antisocial behaviour Low response to effects of alcohol
Clinical presentation of someone with alcohol use disorder
Withdrawal symptoms Tolerance established Change in liver size Jaundice Acsites Nictoine dependance Hyper tension and tachycardia Broad gait Social/pysch problems Impaired nutritional status Nausea and vomiting