Mental Health Flashcards

1
Q

Types of depressive disorder

A

Major: >= 5 symptoms
Minor: 2-4 symptoms
Persistent: 2 years of symptoms

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2
Q

Epidemiology and depression

A

Leading cause of disability and premature death in 18-44o

2:1 F:M ratio

20% of adults will require medical intervention at some point in their life

2-3x more likely to become depressed if a first degree relative has it

First onset most common in 18-24yo and >65

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3
Q

Pathophysiology of depression

A

Abdnormal levels of neurotransmitter + dysregulation of HPA + abnormalities of secondary messengers

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4
Q

Methods for screening depression

A

PHQ-2 which may lead to PHQ-9

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5
Q

Risk factors for depression

A
Aged >65
Postnatal
Female
Coritcosteroid use
Propranolol use
1st degree relative affected
Poor lifestyle
Oral contraception
Co-existing medical conditions which may make you sad
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6
Q

Clinical presentation of someone with depression

A
Low mood
Weight change
Libido change
Anhedonia
Functional impairment
Sleep disturbance
Low energy
Excessive guilt
Suicidal thoughts
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7
Q

Investigations to consider in depression

A

Bloods: TFTs, FBC, U+E

PHQ2/9 + other questionnaires

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8
Q

Management of depression

A

If severe: hospitalise + refer + 2nd or 3rd get antidepressants i.e. SSRIs or SNRIs

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9
Q

Definition of general anxiety disorder

A

> =6 months of excessive worry about everyday issues that are disproportionate to any inherent risk

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10
Q

Symptoms for anxiety disorder

A
Excessive worry
Muscle tension
Sleep disturbance
Fatigue
Restlessness
Poor concentration
Irritability
Anxiety not confined to any other condition or substance
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11
Q

Investigations to consider in anxiety

A

Usually made from clinical picture
TFTs
FBC
Urine drug screen

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12
Q

Management of anxiety disorder

A

1st: Pharmacotherapy w/ SSRI / SNRI or tricyclic if others are CI
2nd: CBT
3rd: Augmented treatments

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13
Q

What is alcohol use disorder

A

Chronic relapsing condition resulting from multifactorial components, characterised by increased tolerance to the effects of alcohol and impaired control over consumption

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14
Q

Epidemiology of alcohol use disorder

A

Common
7-12% prev. in west
M:F 2:1
3.2% of global deaths due to alcoholism

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15
Q

Pathophysiology of alcohol use disorder

A

Increased use of alcohol sensitises dopaminergic pathway = dependance

Long term exposure increases excitatory receptors and noradrenaline activity

Withdrawal of alcohol leaves excitatory receptors unposed = symptoms of withdrawal

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16
Q

Risk factors for alcohol use disorder

A
\+ve FHx
Anxiety
Lack of facial flushing on consumption of alcohol
Antisocial behaviour
Low response to effects of alcohol
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17
Q

Clinical presentation of someone with alcohol use disorder

A
Withdrawal symptoms
Tolerance established
Change in liver size
Jaundice
Acsites
Nictoine dependance
Hyper tension and tachycardia
Broad gait
Social/pysch problems
Impaired nutritional status 
Nausea and vomiting
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18
Q

Investigations to consider in alcohol use disroder

A

Diagnostic interview with DSM-5
Alcohol level blood test
Withdrawal assessment

19
Q

Management of an acute presentation of alcohol use with severe withdrawal

A

Detox
Supportive medical care
Inpatient speciality treatment

20
Q

Management of a problematic alcohol abuse with mild dependance

A

Physician advice + brief interventions

21
Q

Moderate to severe dependance on alcohol: management

A

Psychological intervention + medication to prevent relapse and support abstinence i.e. Naltrexone

22
Q

What is alzheimers?

A

A chronic, neurodegenerative disease, with insidious onset and progressively slow decline.

23
Q

Which is the most common form of dementia?

A

Alzheimers

24
Q

What are some epidemiological facts RE AD

A

Common
6% >65yo
30% > 90yo
Occurs more commonly in women and blacks

25
Q

Aetiology of AD

A

Amyloid theory currently prevails

Excess amyloid peptide = formation of plaques = inflammation = synaptic and neuritic injury and cell death

26
Q

Pathophysiology of AD

A

Cortical atrophy apparent in the temp., frontal and parietal areas only
Plaques and neurofib. tangles found on autopsy

27
Q

Screening method for AD

A

MMSE

28
Q

Risk factors for AD

A
Increased age
\+ve FHx
Genetics (presenelin 1/2)
Downs
CVD
Hyperlipidemia
29
Q

Clinical presentation of AD

A
Memory loss
disorientation 
misplacing items
getting lost
dysphasia
apathy
personality change
mood change
dyspraxia
30
Q

Investigations in AD

A
Bedside cognitive testing
FBC to rule out anaemia
Metabolic panel to rule out metabolic dementia
B12
CT/MRI
31
Q

Management of AD

A
  1. support
  2. environmental control
  3. cholinesterase inhibitors
32
Q

What is vascular dementia

A

Chronic progressive disorder of the brain, brining about cognitive impairment, where cognitive function is affected more than memory

33
Q

Epidemiology of vascular dementia

A

2-% of all dementias
Men more affected than women
Asians/Blacks > Whites

34
Q

Causes of vascular dementia

A

Often multifactorial

  • infarction
  • disease of the white matter
  • haemorrhage
  • AD
35
Q

Risk factors for vascular dementia

A

Age >60
Obesoty
HTN
Smoker

36
Q

Investigations in vascular dementia

A
FBC
ESR
Glucose
LFTs
Renal
Syph. serology
B12
Folate
Thyroid
CT/MRI
ECG
37
Q

Clinical presentation of vascular dementia

A
Inability to solve problems
Loss of interest
Slower processing
Poor attention
Memory retrieval difficulty
38
Q

Management of vascular dementia

A

Treat any underlying cause or predisposing factors

39
Q

Clinical presentation of Lewy Body Dementia

A
Visible hallucinations
Extrapyrmaidal signs
Depression
cognitive impairment
Antipsychotic sensitivity
40
Q

Management of Lewy Body dementia

A

Cholinesterase inhibitors

41
Q

Causes of Delerium

A

DELIRIUMS

Drugs
Eyes/ears and other sensory deficits
Low O2
Infection
Retention
Ictal
Under hydration/nutrition
Metabolic
Subdural haemorrhage
42
Q

management of delirium

A

Correct the initial cause

43
Q

What is delirium?

A

Acute, fluctuating change in mental status with inattention, disorganised thinking, and levels of consciousness

44
Q

Clinical presentation of delirium

A
Disorentiation to time, place and person
Reversal of sleep wake cycle
Labile mood
Illusions, delusions and hallucinations 
Cognitive impairment