Menstual Cycle Flashcards
Ovulation
Estrogen levels increase during late follicular phase until they reach a level that causes a positive feedback increase spike of GnRH, LH, and FSH. Surge in LH causes ovulation
Follicular phase
Begins with menstrual flow
GnRH secretion from hypothalamus in response to low estrogen and progesterone leases to secretions of LH and FSH which develop follicles. Follicles produce estrogen which through negative feedback lower GnRH, LH, and FSH levels. Estrogen retries endometrial lining
Luteal phase
After ovulation, LH causes ruptured follicle to form corpus luteum which secretes progesterone which maintains uterine lining. Estrogen remains high, progesterone levels increase. High levels of progesterone and estrogen cause decrease in GnRH FSH and LH (prevent second ovulation)
Menstruation
If implantation does not occur hCG not made and does not stimulate corpus luteum- progesterone levels decline and uterine lining is sloughed off. GnRH levels rise and cycle starts again
Pregnancy
If fertilization occurs, hCG (secreted by blastula) maintains corpus luteum. Corpus luteum secretes estrogen and progesterone during 1st trimester. 2nd trimester, hCG decline, but placenta continues secreting estrogen and progesterone–inhibits GnRH secretion