Menopause Flashcards

1
Q

how long must you have no menses to have menopause?

A

12 mos

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2
Q

what is perimenopause?

A

irregular cycles

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3
Q

when is stage 1 of perimenopause?

A

13 years prior to menopause

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4
Q

when is stage 2 of menopause?

A

1-8 yrs before menopause

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5
Q

what is median age of menopase?

A

51

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6
Q

what happens to inhibin levels in perimenopause 1?

A

decreased

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7
Q

what happens to FSH levels in perimenopause 1?

A

increased day 3

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8
Q

what happens to LH levels in perimenopause 1?

A

normal

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9
Q

what happens to estrogen levels in perimenopause 1?

A

increased

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10
Q

what happens to cycle length in perimenopause 1?

A

shortened

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11
Q

what happens to inhibin levels in perimenopause 2?

A

decreased

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12
Q

what happens to estrogen/progesterone levels in perimenopause 2?

A

decreased

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13
Q

what happens to FSH/LH levels in perimenopause 2?

A

increased

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14
Q

what happens to cycle length in perimenopause 2?

A

increased

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15
Q

what happens to estrogen and progesterone in menopause?

A

decreased

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16
Q

what happens to LH/FSH in menopause?

17
Q

what happens to SHBG in menopause?

18
Q

what happens to androgen/estrogen ration in menopause?

19
Q

what is vasomotor instability?

A

hot flashes/night sweats

20
Q

how can we manage menopause vasomotor instability?

A

hormone therapy…estrogen

21
Q

what are the atrophic skin changes in menopause?

A

itching/burning/irritaiton of genitals
vaginal bleeding and frequent UTIs
vaginal DRYNESS

22
Q

why is there atrophic skin changes in menopause?

A

decreased estrogen leads to decreased collagen

23
Q

how does hormone therapy change LDL, HDL, triglyceride and total cholesterol levels?

A

low LDL
high HDL
high triglycerides
low total cholesterol

24
Q

how long can you give hormone replacement therapy?

A

max is 5 years

25
why is there a max duration of hormone therapy?
increased breast cancer risk
26
how are LDL and total cholesterol affected by menopause?
both increase
27
when is it considered premature ovarian failure to have menopause?
before age 40
28
what will FSH and estrogen levels be in premature ovarian failure?
low estrogen and high FSH
29
what is the most common cause of premature ovarian failure?
Unkown cause
30
what is a common genetic issue cause of premature ovarian failure?
fragile X mutation
31
what are some other causes of premature ovarian failure to consider?
chromosome abnormalities | autoimmune diseases
32
what autoimmune diseases can cause premature ovarian failur?
Thyroid disesae | anti adrenal antibodies