Menopause Flashcards

1
Q

how long must you have no menses to have menopause?

A

12 mos

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2
Q

what is perimenopause?

A

irregular cycles

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3
Q

when is stage 1 of perimenopause?

A

13 years prior to menopause

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4
Q

when is stage 2 of menopause?

A

1-8 yrs before menopause

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5
Q

what is median age of menopase?

A

51

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6
Q

what happens to inhibin levels in perimenopause 1?

A

decreased

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7
Q

what happens to FSH levels in perimenopause 1?

A

increased day 3

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8
Q

what happens to LH levels in perimenopause 1?

A

normal

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9
Q

what happens to estrogen levels in perimenopause 1?

A

increased

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10
Q

what happens to cycle length in perimenopause 1?

A

shortened

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11
Q

what happens to inhibin levels in perimenopause 2?

A

decreased

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12
Q

what happens to estrogen/progesterone levels in perimenopause 2?

A

decreased

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13
Q

what happens to FSH/LH levels in perimenopause 2?

A

increased

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14
Q

what happens to cycle length in perimenopause 2?

A

increased

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15
Q

what happens to estrogen and progesterone in menopause?

A

decreased

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16
Q

what happens to LH/FSH in menopause?

A

increased

17
Q

what happens to SHBG in menopause?

A

decreased

18
Q

what happens to androgen/estrogen ration in menopause?

A

increased

19
Q

what is vasomotor instability?

A

hot flashes/night sweats

20
Q

how can we manage menopause vasomotor instability?

A

hormone therapy…estrogen

21
Q

what are the atrophic skin changes in menopause?

A

itching/burning/irritaiton of genitals
vaginal bleeding and frequent UTIs
vaginal DRYNESS

22
Q

why is there atrophic skin changes in menopause?

A

decreased estrogen leads to decreased collagen

23
Q

how does hormone therapy change LDL, HDL, triglyceride and total cholesterol levels?

A

low LDL
high HDL
high triglycerides
low total cholesterol

24
Q

how long can you give hormone replacement therapy?

A

max is 5 years

25
Q

why is there a max duration of hormone therapy?

A

increased breast cancer risk

26
Q

how are LDL and total cholesterol affected by menopause?

A

both increase

27
Q

when is it considered premature ovarian failure to have menopause?

A

before age 40

28
Q

what will FSH and estrogen levels be in premature ovarian failure?

A

low estrogen and high FSH

29
Q

what is the most common cause of premature ovarian failure?

A

Unkown cause

30
Q

what is a common genetic issue cause of premature ovarian failure?

A

fragile X mutation

31
Q

what are some other causes of premature ovarian failure to consider?

A

chromosome abnormalities

autoimmune diseases

32
Q

what autoimmune diseases can cause premature ovarian failur?

A

Thyroid disesae

anti adrenal antibodies