Meningitis Flashcards
What is meningism?
Symptom complex of: headache, photophobia and vomiting with muscle spasm leading to neck rigidity
What is meningitis?
Infection of the meninges leading to inflammation and signs of meningeal irritation
What are the bacterial causes of meningitis?
Neisseria meningitidis (meningococcus)
Strep. pneumonia (pneumococcus)
What are the viral causes of meninigitis?
Enteroviruses
Mumps
HSV
What is aseptic meningitis>
CSF shows an excessive number of lymphocytes and elevated protein
No causative organism
May be due to tumour cells in CSF, a reaction to drugs, sarcoidosis, SLE
What is the definitive diagnosis for meningitis?
Lumbar Puncture- examination of the CSF
What is the management of acute bacterial meningitis?
Early clinical recognition
Rapid pathogen detection
Bactericidal antimicrobial therapy
Treat sequelae of septicaemia
Antibiotic prophylaxis of close contacts
What is the primary cause of disease in nenoates?
Group B streptococcus )GBS)
What is the primary cause of disease in children and young people?
Neisseria meningitidis- meningococcus
What is the primary cause of disease in adults?
Streptococcus pneumonia (pnuemococcal)
What is another type of bacterial meningitis?
Haemophilus influenzae (Type b) Meningitis
What is meningococcal septicaemia?
Meningococcal bacterial infection is in the bloodstream
Causes the non blanching rash
What is Kernig’s test?
Tests meningeal irritation:
Patient lies on back. Flex one hip and knee to 90 degrees and then slowly straighten the knee while keeping the kip flexed.
In meningitis this produces spinal pain
What is Brudzinski’s test?
Tests meningeal irritation:
Lift head and neck off the bed and flex their chin to their chest
Positive test is when this causes the patient to involuntarily flex their hips and knees
What are CSF results for bacterial meningitis?
Cloudy
High protein
Low glucose
High neutrophil count
Bacteria culture positive
What are CSF results for viral meningitis?
Clear
Mildly raised or normal protein
Normal glucose
High lymphocyte count
Negative bacterial culture