Gastroenteritis Flashcards
What is gastroenteritis?
Inflammation of the stomach and intestines
Presents with nausea, vomiting and diarrhoea
What is the most common form of gastroenteritis?
Viral
What viruses cause gastroenteritis?
rotavirus
Norovirus
Adenovirus
What bacteria causes gastroenteritis?
E. coli
Campylobacter jejuni
Shigella
Salmonella
Staph aureus.
What is the pathology of E.coli?
E. coli 0157 produces the Shiga toxin
Causes abdominal cramps, bloody diarrhoea, vomiting
What is a major side effect of E. coli 0157
Haemolytic uraemic syndrome (HUS)
Shiga toxin destroys RBCs
What is HUS?
Renal failure
Haemolytic anaemia
Thrombocytopenia
Should antibiotics be used in E.coli infection?
Increases risk of HUS so should be avoided
What bacteria causes traveller’s diarrhoea?
Campylobacter
What are the symptoms of campylobacter jejuni?
Abdominal cramps
Diarrhoea with blood
Vomiting
Fever
How is shigella spread?
Faeces contaminating drinking water, swimming pools and food
What are the symptoms of shigella?
Bloody diarrhoea
Abdominal cramps
Fever
How is salmonella spread?
Eating raw eggs or poultry and food contaminated with infected faeces
What are the symptoms of salmonella?
Watery diarrhoea <10 days
Abdominal pain
Vomiting
How is staph aureus spread?
Staph aureus produces enterotoxins when growing in food such as eggs, dairy and meat
The enterotoxin causes the enteritis not the bacteria
What are the symptoms of staph aureus enterotoxins?
Diarrhoea
Perfuse vomiting
Abdominal cramps
Fever
What parasites can cause gastroenteritis?
Giardia lamblia
Cryptosporidium parvum
Entamoeba histolytica
What is giardiasis?
Infection with giardia lamblia parasite
Releases cysts in the stools of infected mammals which contaminate food or water- faecal oral transmission
What is cryptosporidiosis?
Ingestions of oocytes in faeces contaminated water
What are the principles of management?
Good hygiene
Isolate patients
Blood culture and microscopy
Fluid challenge (rehydration)
Antibiotics in patients at risk of complications
What are some post-gastroenteritis complications?
Lactose intolerance
IBS
Reactive arthritis
Guillain Barre syndrome