Mening Flashcards

1
Q

Meningococcal disease symptoms

A
  • Meningitis
  • Bacteremia
  • Bacteremic pneumonia
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2
Q

Meningitis symptoms

A

pain, headache, neck stiffness

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3
Q

Bacteremia symptoms

A

sepsis and rash

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4
Q

Meningococcal Vaccines

A

A, C, Y, W-135
Polysaccharide (MPSV4) - removed from market
and
Conjugate (MCV4)

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5
Q

dosing is different for

A

adolescents and adults with certain med conditions

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6
Q

all adolescents

A

2 and 4 dose options for babies

1 dose of MCV4 at age 11-12
1 booster of MCV4 at age 16

only 1 dose if 1st dose after age 16 yrs - not routinely recomm after 19 yrs

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7
Q

adults with certain med conditions

A

2 doses at least 8 weeks apart

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8
Q

children at cont’d risk for mening disease who were prev vacc with MCV4

A

additional dose after 3 yrs if 1st was admin at age 2 to 6

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9
Q

persons who have completed the 2-dose primary series and remain at continued risk for meningococcal disease

A

revaccinate every 5 yrs after the last dose of the primary series

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10
Q

Persons with persistent complement component deficiency or anatomic or functional asplenia

A

1 dose every 5 yrs after completing 2-dose primary series

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11
Q

HIV patients over the age of 2 mo

A

Men ACYW-135

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12
Q

two new mening B vaccs licensed by FDA for ages

A

10-25

2-dose and 3-dose options

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13
Q

ACIP recommends routine use of MenB vaccines

A

during outbreaks

college campuses that have recently experienced an outbreak of serogroup B meningococcal

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14
Q

Notes about meningococcal b vacc

A
  • must complete series with same vacc
  • can be given at same time with other vaccs, diff sites
  • both men B vaccs recommended for high-risk patients > 10 yrs
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15
Q

Men B not routinely recommended for

A

travelers, HIV patients, revaccination

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16
Q

CDC recommendations for Men B in an outbreak

A

no upper age limit

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17
Q

Measles

A

Paramyxovirus

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18
Q

Clinical features

A

respiratory transmission

highly contagious 4 days b4 to 4 days after rash onset

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19
Q

incubation

A

10-12 days

20
Q

Early signs

A

(2-4 days) fever 103 or higher,

followed by cough, runny nose, swelling around eye

21
Q

Other sign

A

Rash - first appears in mouth (koplik spots)

22
Q

measles complications

A
diarrhea
otitis media
pneumonia
encephalitis
death 
hospitalization
23
Q

Mumps

A

Paramyxovirus

24
Q

Clinical feat

A

respiratory transmission

contagious 3 days before to 4 days after onset

25
incubation
14-18 days
26
prodrome
myalgias, anorexia, headache low-grade fever
27
in first 2 days
parotitis
28
20%
asymptomatic
29
mumps complications
``` cns involvement orchitis oophoritis deafness myocarditis death ```
30
Rubella
Togavirus (german measles, 3-day measles)
31
clinical features
resp transmission (contagious 7 days before rash and 5-7 days after onset
32
incubation
14 days (12-23 range)
33
Prodrome
rare in children | ow-grade fecer, malaise, URI symptoms
34
Rash
musculopapular starts on face then spreads from head to foot duration 3 days
35
rubella complications
arthralgia or arthritis in adult women | congenital rubella syndrome (cataracts, heart defects, deafness, mental retardation, miscarriage)
36
MMR vaccine
(merck) live-attenuated
37
dose
2 dose series for children at 12-15mo then 4-6 yrs of age second dose not a booster, but to revaccinate non-responders adults born before 1957 immune born later must have documentation of 1 or more doses of MMR
38
Contraindications
allergy to gelatin or neomycin, pregnancy, immunosuppression, receipt of blood products
39
what are the target groups for MMR vaccination
all children all susceptible people at high risk (e.g. health care personnel, college students, travelers, patients with HIV if cd4 count adeq) adults born n 1957 or later who have never been vacc
40
should a patient with provider-diagnosed measles, mumps, or rubella be considered immune
adults born before 1957 considered immune adults born in 1957 or later lab evidence or documentation is required, provider diagnosis not adeq.
41
all children
2 doses
42
all susceptible patients at high risk for disease
2 doses
43
health care personnel born before 1957
consider 2 doses
44
adults born in 1957 or later who have not been vacc with MMR
at least 1 dose recommended | 2nd dose if a risk factor is present
45
recc dose and route of admin for MMR
0.5 ml SC