Herpes Zoster

Question 1

Herpes Zoster mode of action

Answer 1

latent in cells of dorsal root ganglia then reactivates and travels along neuronal cell axons

• often activated at older age or weakened immune system

Question 2

Herpes Zoster infection appears as

Answer 2

localized rash on skin along spinal nerve

Question 3

Herpes Zoster complications

Answer 3

neuralgia
scarring
bact infec
ocular abmormalities

Question 4

Zoster Vaccine

Answer 4

Zostavax (Merck) which is a live attenuated virus, higher strength than varicella vacc

Question 5

ACIP target group for vacc

Answer 5

adults 60 and older

Question 6

FDA target

Answer 6

for prevention (not treatment0
adults 50 and older

Question 7

Dose and route for Zostavax (Merck)

Answer 7

0.65 ml (entire contents of vial) SC

Question 8

_ can’t be administered concurrently

Answer 8

pneumovax 23 and zostavax

Question 9

_ can

Answer 9

zoster and pneumococcal vaccines

Question 10

can patients who rec’v the herpes zoster vacc transmit the varicella virus (chickenpox) to susceptible persons

Answer 10

no

but if the patient develops a rash after vaccination indicating the vacc wasn’t 100% effective, rash should be covered