Memory & Cognition Flashcards
What is the NT change w/ Anxiety?
- Dec NE
- Inc GABA
- Dec serotonin (5-HT)
What are the NT changes w/ Depression?
- Dec NE
- Dec serotonin (5-HT)
- Dec dopamine
What are the NT changes w/ Alzheimer’s?
Dech ACh, NE & Glutamate
What are the NT changes w/ Huntington’s?
- Dec GABA
- Dec ACh
- Inc dopamine
What are the NT changes w/ Schizophrenia?
Inc Dopamine
What are the NT changes w/ Parkinson’s dz?
- Dec dopamine
- Inc serotonin
- Inc ACh
What is Orientation?
Pt’s ability to know who & where he/she is & the date/time
What are the common causes of loss of orientation?
- Alcohol
- Drugs
- Fluid/electrolyte imbalance
- Head trauma
- Hypogylcemia
- Nutritional deficiencies
What is the order of loss of orientation?
- Time
- Place
- Person
What is Retrograde amnesia?
Inability to remember things taht occured before a CNS insult
What is Anterograde amnesia?
Inability to remember things that occured AFTER a CNS insult (no new memory)
What is Korsakoff’s amnesia?
Classic anterograde amnesia caused by Thiamine (B1) def & assoc destruction of mamillary bodies. May also have retrograde amnesia
What is Korsakoff’s amnesia assoc w/?
Alcoholics & confabulations
What is Dissociative amnesia?
Inability to recall important personal info, usually subsequent to severe trauma or stress
What is a Cognitive disorder?
Significant change in cognition from previous level of functioning
(Delirium & dementia)
What is cognition?
Memor, attention, language & judgement
What are cognitive disorers assoc w/?
- ABN in CNS
- General medical cond
- Medications
- Substance use
What is Delirium?
Waxing & waning level of consciousness w/ acute onset; rapid dec in attention span & level of arousal
What is Delirium characterized by?
- Disorganzied thinking
- Hallucinations (often visual)
- Illusions
- Misperceptions
- Disturbance in sleep-wake cycle
- Cognitive dysfunction
Delirium is usually 2° to ____ ____.
Other illness
What is the MC presentation of altered mental status in an inpatient setting?
Delirium
What are the tech features of Delirium?
ABN EEG
What is the tx for Delirium?
- Identify & address underlying cause
- Optimize brain cond
- Antipsychotics (haloperidol)