Membranes Flashcards
What makes up a membrane?
Phospholipids and proteins make up the phospholipid bilayer
How wide are membranes?
7nm
What are membranes seen as on an electron microscope?
Two dark bands
What are the four functions of membranes?
- Selectively permeable barrier
- Taking up nutrients
- Secreting chemicals
- Cell to cell recognition (to avoid pathogens)
Is the phosphate group on a phospholipid hydrophilic or hydrophobic?
Hydrophilic
Is the fatty acid on a phospholipid hydrophilic or hydrophobic?
Hydrophobic
What is the function of the phospholipid bilayer?
Acts as a barrier to large polar molecules
What is the diagram of the plasma membrane called?
The fluid mosaic model
What is the function of the phospholipids in the plasma membrane?
Creates the bilayer
What is the function of the glycoproteins in the plasma membrane?
Used for cell to cell recognition
What is the function of the glycolipids in the plasma membrane?
Used for cell to cell recognition
What is the function of carbohydrates in the plasma membrane?
Used for cell to cell recognition
What is the function of cholesterol in the plasma membrane?
Makes the membrane stable and fluid
What is the function of extrinsic proteins in the plasma membrane?
Likely to be enzymes or structural material in the cytoskeleton
What is the function of channel forming proteins in the plasma membrane?
Hydrophilic pores that allows polar molecules through the membrane
What is the function of the phospholipid bilayer?
Creates a selectively permeable membrane
What is the function of channel proteins?
Allow polar molecules across the membrane
What is the function of carrier proteins?
Used in active transport and facilitated diffusion
What is the function of receptor proteins?
For hormones, a specific 3D shape complementary to molecules such as hormones
What are the four roles of internal membranes?
- Separate components from cytoplasm for specialisation
- Holds metabolic pathways in place. Chemical reactions take place on membranes
- Ribosomes are attached to membranes (SER)
- Control of movement of substances
Define diffusion?
The movement of molecules or ions from a region of high concentration to a region of low concentration down a concentration gradient
What type of molecules can be moved by diffusion? (2)
.Small non-polar molecules
.Large lipid soluble molecules
Does diffusion require ATP?
No
Does diffusion require specific proteins?
No
What are two requirements for diffusion to occur?
- A concentration gradient
2. Molecules have kinetic energy
Give three named examples of molecules that can move by diffusion across a membrane?
O2, CO2, H2O
What six factors affect the rate of diffusion?
- Temperature
- Concentration Gradient
- Surface Area
- Diffusion Distance
- Size of Molecules
- Lipid solubility
How does temperature affect the rate of diffusion?
Increasing temperature increases kinetic energy and this the rate of diffusion
How does concentration gradient affect the rate of diffusion?
Having more molecules on one side of the membrane than the other increases diffusion rate (increasing concentration gradient)
How does surface area affect the rate of diffusion?
The greater the surface area, the greater the rate of diffusion
How does diffusion distance affect the rate of diffusion?
The shorter the diffusion distance the greater the rate of diffusion
How does size of the molecule affect the rate of diffusion?
Smaller molecules diffuse faster than larger ones. Smaller molecules have more kinetic energy
How does lipid solubility affect the rate of diffusion?
Ions can only diffuse across a membrane if the specific channel for their transport is present in the membrane. The ion channels are very specific.
Define osmosis?
The movement of water from an area of high water potential to an area of ow water potential, down a water potential gradient, across a selectively permeable membrane.
What is water potential?
The tendency of water molecules to leave or enter a system
What unit is water potential measure in?
Kilopascals (Kpa)
What has the high water potential of 0Kpa?
Distilled Water
The more negative the number the more what the water potential?
The lower the water potential
What is a solvent?
A substance that dissolves it
What is a solute?
A substance that dissolves in the solvent
What is a hypertonic solution?
They have a lower water potential than the cell cytoplasm. It contains many solutes.
What is a Isotonic solution?
They have the same water potential as the cell cytoplasm. It contains the same concentration of solutes.
What is a hypotonic solution?
They have a higher water potential than in the cell cytoplasm. It contains more solutes.
What is facilitated diffusion?
Diffusion that requires either a channel forming protein or a carrier protein
Why do channel forming proteins allow for facilitated diffusion?
Channel forming proteins form hydrophilic pores to allow small polar molecules or small ons to move across the membrane.
Why do carrier proteins allow for facilitated diffusion?
These have a binding site specific to a large polar molecule. They change shape (a conformational change) and deliver molecules to the other side of the membrane.
What are the requirements for facilitated diffusion?
- Concentration Gradient
- Kinetic Energy
- No ATP
- Channel or Carrier protein
Define Co-transport?
A type of facilitated diffusion in which two substances are simultaneously transported across a membrane by one protein complex, that does not have ATPase activity.
Define Active transport?
The movement of ions and other molecules across the membrane via carrier proteins. Substances can be moved from low to high, against a concentration gradient. It requires ATP.
What are 5 facts about active transport?
- Requires ATP
- Against a concentration gradient
- Molecules have kinetic energy
- Protein carriers are present
- If a respiratory inhibitor is present, active transport will no longer take place.
What are two named examples of active transport use?
- Nerve impulse transmittion
2. Absorption of mineral salts by plant roots
What is the case study example of a respiratory inhibitor?
Cyanide
Define bulk transport?
The process by which the cell obtains solid or liquid materials that are too large to enter by diffusion or active transport.
What are two examples of bulk transport?
- Phagocytosis - solid materials
2. Pinocytosis - liquids
What are four facts for bulk transport?
- Membrane engulfs the material
- Membrane fuses together
- Vesicle is formed
- ATP required