Membrane Transport Flashcards

1
Q

The boundary between the cells intracellular spaces and the extracellular matrix

A

Cell membrane

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2
Q

What is the permeability of the Plasma Membrane?

A

Differentially(selectively) permeable

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3
Q

Factors that determine how a substance may be transported across the plasma membrane

A
  • Size
  • Polarity (polar/non-polar)
  • Solubility
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4
Q

Governs all biological systems. “Universe tends towards disorder(entropy). Movement from high to low concentration

A

2nd Law of Thermodynamics

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5
Q

Diffusion of small, relatively hydrophobic molecules across a phospholipid bilayer at significant rates.

A

Passive Diffusion

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6
Q

Molecules that can diffuse through the plasma membrane

A

Gases, Water molecule, Lipids, lipid soluble molecules, Small non-charged molecules

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7
Q

Diffusion with the aid of proteins that do not interact with the hydrophobic interior

A

Facilitated Diffusion

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8
Q

Diffusion used by biological molecules that are unable to dissolve in the hydrophobic interior. No energy needed

A

Facilitated Diffusion

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9
Q

Facilitated = __________
Open Channel = __________

A

With help
fast transport

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10
Q

Passage of materials aided by both a concentration gradient and a transport protein

A

Facilitated Diffusion

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11
Q

Protein that transport glucose in and out of the cell. Mostly found on erythrocytes.

A

Glucose Transporters

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12
Q

Two kind of transport proteins:

A
  1. Carrier Proteins
  2. Channel Proteins
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13
Q

Bind specific molecules, undergo conformational change to release molecule.

A

Carrier Proteins

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14
Q

Transport protein that form open pores for free diffusion, found in gap junctions

A

Channel Proteins

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15
Q

Bond and drag molecules through the lipid bilayer and releases them on the other side.

A

Carrier proteins

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16
Q

Channel Proteins allow:

A

ions, small solutes, and water

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17
Q

Facilitated Diffusion is limited due to:

A

Presence of protein channels

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18
Q

Carrier proteins allows:

A

glucose and amino acids

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19
Q

Functions of Facilitated Diffusion

A
  • Food for cell respiration
  • Communication of neurons
  • Small intestine food transport to the bloodstream
  • Muscle cells contract
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20
Q

Protein corridors that allow the fast movement of water molecules across the membrane.

A

Aquaporins

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21
Q

Protein pores used by the cells during Osmosis

A

Aquaporins

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22
Q

Diffusion of water across a differently permeable membrane

A

Osmosis

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23
Q

Pressure that develops in a system due to osmosis

A

Osmotic Pressure

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24
Q

Different concentrations of water

A
  1. Hypertonic
  2. Isotonic
  3. Hypotonic
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25
Equal water and solution mixture
Isotonic
26
Less solute, more water
Hypotonic
27
More solute, less water
Hypertonic
28
Animal cell and plant cell state when force in a hypotonic solution
Lysed, Turgid
29
State of animal cells and plant cells in an isotonic solution:
Normal, Flaccid
30
State of animal cells and plant cells in a hypertonic solution
Shriveled, Plasmolyzed
31
Organelle that pumps the water out of the cell with the help of ATP
Contractile Vacuole
32
A unicellular organism that live constantly on Hypotonic state of water
Paramecium cells
33
Molecules that passively diffuse down their electrochemical gradient through channels that cross the lipid bilayer.
Non-lipid soluble substances
34
Regulates the opening and closing of voltage gated channels:
Membrane Potential
35
Voltage regulates the opening and closing of ____________ channel
Voltage-Gated Channel
36
Gated channel that activates to a stimuli created by ligand
Ligand-Gated Channel
37
Gated channel proteins that act to a specific stimuli
Specific-Activated Channels
38
Permits the passage of ions and small polar molecules through the membranes of bacteria
Porins
39
Mediates the passage of ions across plasma membranes
Ion channels
40
Channels that open in response to the binding of neurotransmitters or other signaling molecules
Ligand-Gated channels
41
Channels that open in response to changes in electric potential across the plasma
Voltage-gated channels
42
Protein channels that open or close depending on the presence or absence of physical or chemical stimulus (released by neurotransmitters)
Gated Channels
43
if not present, the gated channels are closed
Neurotransmitters
44
Diffusion that allows molecules to move against the concentration gradient
Active Transport
45
Importance of Active Transport
1. Brings essential molecules 2. Rid cells of unwanted molecules 3. Maintain internal conditions 4. Regulate cell count 5. Re-establish concentration gradient
46
2 groups of active transport
1. Primary Active Transport 2. Secondary Active Transport
47
Active transport that uses ATP to stimulate the protein that moves substances against the concentration gradient from an area of low to high concentration
Primary Active Transport
48
Active transport that uses two channel proteins and the energy of a molecule that diffuses passively to move another molecule against the concentration gradient.
Secondary Active Transport
49
Class of Secondary Active Transport that moves two molecules in the same direction across a concentration gradient
Symporter
50
A secondary molecule utilizes the energy from a primary molecule that diffuses passively to move to a similar direction
Symporter
51
Two substances move against each other across the plasma membrane
Antiporter
52
One of the substance moves passively down its concentration gradient while the second substance uses ATP to move against its concentration gradient across the plasma membrane.
Antiporter
53
Transporter that can only transport a single molecule using facilitated diffusion of glucose
Uniporter
54
Cotransport proteins:
Symport and Antiport
55
Transports of molecules outside the cell and keeps macromolecules contained
Vesicle Formation
56
Formation of vesicles as a way to transport molecules out of the cell
Exocytosis
57
The substances that are transported by exocytosis
Neurotransmitters, hormones, and digestive enzymes
58
This is how many hormones are secreted and how nerve cells communicate with each other
Exocytosis of proteins
59
Vesicles form as a way to transport molecules into the cell
Endocytosis
60
Endocytosis of Large particulate matter (e.g. Bacteria, viruses, or dead cells) also known as "Cell Eating"
Phagocytosis
61
Endocytosis of liquids and small particles dissolved in liquid (cell drinking).
Pinocytosis
62
Ligand-receptor complexes triggers infolding of a clathrin pit that forms a vesicle containing ligands such as: vitamins, hormones, and anti-bodies
Receptor Mediated Endocytosis
63
Most common form of endocytosis. Materials dissolved in water to be brought into the cell.
Pinocytosis
64
Vesicles that are used to move molecules inside the cell are coated with the protein ________
Clathrin
65
A form of pinocytosis, provides a mechanism for the selective uptake of specific macromolecules.
Receptor mediated endocytosis
66
Specialized regions of the plasma membrane where specific cell receptors are found
Clathrin-coated pits
67
A membrane associated with GTP-binding protein that assists the budding off of the pits from the plasma membrane
Dynamin
68
Clathrin-coated pits occupy about ________% of the surface area of plasma membranes
1% - 2%
69
Vesicles with tubular extensions located at the periphery of the cells that fuse with clathrin-coated vesicles.
Endosomes
70
Maintains the acid internal pH caused by the action of a membrane H+ pump.
Endosomes
71
A phenomenon where receptor-ligand complexes are removed from the plasma membrane, terminating the response of the cell to growth factor stimulation
Receptor-down regulation
72
Phagosomes that infused fused to lysosomes, contains lysosomal acid hydrolases that digest ingested material.
Phagolysosomes
73
Moves chlorine ions outside of the cell
CFTR Channels
74
Disease caused by the failure of CFTR channels to pump chlorine out of the cells that leads to the build-up of sticky mucus on the outside of the cell
Cystic Fibrosis
75
Cystic Fibrosis can be passed through?
Genetics/Trait Inheritance