Melana and Hemoxhezia Flashcards
Symptoms of UGIB and LGIB
- UPPER (can present with melena, if rapid can present as hematochezia)
- LOWER (typically present as hematochezia)
DDx for UGIB
- Peptic Ulcer Disease
- Varices (esophageal)
- Hemorrhagic/erosive gastritis
- Mallory-Weiss tear
- Boerhaavesyndrome
- Erosive esophagitis
- Aortoentericfistula
- Arteriovenous malformations/angioectasias
- Cancer (Esophagus, Gastric)
- Swallowed blood (nosebleed aka epistaxis)
- Anticoagulant and fibrinolytic therapy
DDx for UGIB
LOWER (typically present as hematochezia)
- Inflammatory Bowel Disease
- Ischemic colitis
- Diverticulosis bleed
- Anal fissures
- Hemorrhoids
- Polyps
- Cancer (Colon)
- Infectious colitis
- Arteriovenous malformations/angioectasias
- Varices (Colon)
- Radiation colitis
- NSAID-induced ulcers
- Rectal ulcer
- Intussusception
DDx for LGIB depends on the age of the patient and severity of the bleed.
DDx UNDER 50:
- Infectious colitis
-
Anorectal disease
- Anal fissures, hemorrhoids
- IBD
- Meckel diverticulum
DDx for LGIB depends on the age of the patient and severity of the bleed.
DDx OVER 50:
- Cancer
- Diverticulosis
- Angectasias
- Ischemic Colitis
____ of hematochezia due to upper gastrointestinal source
10%
There is an increased risk of LGIB in patients taking _______________.
aspirin, non-aspirin antiplatelet agents, and NSAIDs.
2 weird things that can cause hematochezia and make doc think LGIB
- Liquid meds with red dye, as well as
- certain foods, such as red Kool-aid™ and beets
Diagnostics in ppl with LGIB
Evaluation with colonoscopy in stable patients
UGIB = melana or if rapid, hematochezia. What medications can cause this?
Medications with iron or bismuth
- MVI with iron, Peptobismol
DIFFERENTIAL DX CONSIDERATIONS: HEMATOCHEZIA/MELENA
1 Diverticulosis bleed
2. IBD
3. Ischemic colitis
- Anorectal disease
- Polyps
- Cancer (Colon)
- Arteriovenous malformations/angioectasias
- Upper GIB
- 1.PUD
- 2.Varices
_______ is the most common cause of major lower tract bleeding, most commonly occuring in the ________.
Diverticulosis
Sigmoid Colon
Will all patients with diverticulosis be symptomatic?
No, 90% will have uncomplicated diverticulosis = asymptomatic
Diveritulosis
- Sx
- Diagnostics
- Acute, PAINLESS, large ovlume red poop
- Hemorrage, without diverticulitis, from the ascending colon.
•Evaluation with colonoscopy in stable patients, once bleeding subsides typically
_______ is a CD (Crohns Disaese) related gene on Chr16.
CARD15/NOD2
If patient has primary sclerosing cholangitis, think _____
UC