meds; abx Flashcards

1
Q

Penicillin MOA

A

inhibits cel wall synthesis

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2
Q

DOC for strep, meningococci and pneumonia cocci, mostly gram +, URI, catheter/ skin infections

A

Penicillin-Beta Lactam

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3
Q

Penicillin-Beta Lactam SE

A

resistance due to beta lactamse enzyme
hypersensitivity
GI upset
Vaginal candidas

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4
Q

Cefalosporin Beta lactams MOA

A

inhibits cell wall synthesis by binding to Pencicillin binding protein and inhibiting beta lactamaze

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5
Q

Cefalosporin Beta lactams use

A

surgical prophylaxis
mostly gram +
PCN allergy
doesn’t cross bbb

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6
Q

Cefalosporin Beta lactams SE

A

Production deficit of vitamin K

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7
Q

For true PCN anaphylaxis what meds should you use?

A

vanc or clindamycin

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8
Q

cefazolin trade name

A

ancef

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9
Q

cefuroxime trade name

A

ceftin

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10
Q

cefoxitin trade name

A

mefoxin

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11
Q

cefotetan trade name

A

cefotan

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12
Q

cefotaxime trade name

A

ciaforan

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13
Q

ceftriaxone trade name

A

rocephen

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14
Q

cefazidine trade name

A

foraz

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15
Q

cefepime trade name

A

maxipime

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16
Q

DOC for enterobacter

A

carbopenem

17
Q

DOC with boradest spectrum activity

A

carbopenem

18
Q

Carbopenem use

A

x bbb
last line agent for intrabdominal resistant, utis and pne

19
Q

Carbopenem SE

A

dec depakote (valporic acid) up to 20%
lidocaine allergy (IM injection contains lido)

20
Q

Vancomycin MOA

A

inhibits cell wall synethsis
beta lactamase resistant

21
Q

Vancomycin use

A

Gram + works well if bacteria are actively binding

Blood stream infections

endocarditis caused by MRSA

22
Q

Vanc SE

A

Red man syndrome
nephrotoxicity
phlembitis
chills/feverf

23
Q

Aminoglycosides drug

A

gentamyacin

24
Q

Aminoglycosides MOA

A

inhibits ribosomal proteins and causes mRNA to misread

25
Aminoglycosides USe
good post abx effect synergistic w/ beta lactams and vanc enterococcal endocardidtsi
26
Aminoglycosides SE
curare-like effect ototoxicty nephrotoxicity w/ loop dicuretics
27
ciproflaxacin and levoflaxacin are what type of meds
floroquinolone
28
floroquinolone MOA
inhibits DNA proteins synthesis
29
floroquinolone USE
Gram negative organisms UTI, bacterial diarrhea, bone/ joint infections
30
floroquinolone SE
cartilage damage (tendon rupture in elderly and athelets) long QT
31
Flagyl is what kind of abx
metronidazole
32
Flagyl MOA
forms toxic byproducts that cause unstable dna molecules
33
Flagyl uses
intrabdominal infections, vaginitis, c-diff
34
Flagyl SE
Peripheral neuropathy disflurane like effects with etoh, hangoverm dizziness, flushing, ha, chest/ and pain
35
What abx are administered within 2 hrs of incision
vanc and fluroquinolones