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Clinical prep > meds; abx > Flashcards

meds; abx Flashcards

1
Q

Penicillin MOA

A

inhibits cel wall synthesis

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2
Q

DOC for strep, meningococci and pneumonia cocci, mostly gram +, URI, catheter/ skin infections

A

Penicillin-Beta Lactam

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3
Q

Penicillin-Beta Lactam SE

A

resistance due to beta lactamse enzyme
hypersensitivity
GI upset
Vaginal candidas

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4
Q

Cefalosporin Beta lactams MOA

A

inhibits cell wall synthesis by binding to Pencicillin binding protein and inhibiting beta lactamaze

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5
Q

Cefalosporin Beta lactams use

A

surgical prophylaxis
mostly gram +
PCN allergy
doesn’t cross bbb

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6
Q

Cefalosporin Beta lactams SE

A

Production deficit of vitamin K

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7
Q

For true PCN anaphylaxis what meds should you use?

A

vanc or clindamycin

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8
Q

cefazolin trade name

A

ancef

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9
Q

cefuroxime trade name

A

ceftin

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10
Q

cefoxitin trade name

A

mefoxin

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11
Q

cefotetan trade name

A

cefotan

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12
Q

cefotaxime trade name

A

ciaforan

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13
Q

ceftriaxone trade name

A

rocephen

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14
Q

cefazidine trade name

A

foraz

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15
Q

cefepime trade name

A

maxipime

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16
Q

DOC for enterobacter

A

carbopenem

17
Q

DOC with boradest spectrum activity

A

carbopenem

18
Q

Carbopenem use

A

x bbb
last line agent for intrabdominal resistant, utis and pne

19
Q

Carbopenem SE

A

dec depakote (valporic acid) up to 20%
lidocaine allergy (IM injection contains lido)

20
Q

Vancomycin MOA

A

inhibits cell wall synethsis
beta lactamase resistant

21
Q

Vancomycin use

A

Gram + works well if bacteria are actively binding

Blood stream infections

endocarditis caused by MRSA

22
Q

Vanc SE

A

Red man syndrome
nephrotoxicity
phlembitis
chills/feverf

23
Q

Aminoglycosides drug

A

gentamyacin

24
Q

Aminoglycosides MOA

A

inhibits ribosomal proteins and causes mRNA to misread

25
Q

Aminoglycosides USe

A

good post abx effect

synergistic w/ beta lactams and vanc

enterococcal endocardidtsi

26
Q

Aminoglycosides SE

A

curare-like effect
ototoxicty
nephrotoxicity w/ loop dicuretics

27
Q

ciproflaxacin and levoflaxacin are what type of meds

A

floroquinolone

28
Q

floroquinolone MOA

A

inhibits DNA proteins synthesis

29
Q

floroquinolone USE

A

Gram negative organisms

UTI, bacterial diarrhea, bone/ joint infections

30
Q

floroquinolone SE

A

cartilage damage (tendon rupture in elderly and athelets)

long QT

31
Q

Flagyl is what kind of abx

A

metronidazole

32
Q

Flagyl MOA

A

forms toxic byproducts that cause unstable dna molecules

33
Q

Flagyl uses

A

intrabdominal infections, vaginitis, c-diff

34
Q

Flagyl SE

A

Peripheral neuropathy

disflurane like effects with etoh, hangoverm dizziness, flushing, ha, chest/ and pain

35
Q

What abx are administered within 2 hrs of incision

A

vanc and fluroquinolones

Clinical prep (21 decks)

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