MEDS Flashcards
Side effects of SSRI’s
- N/V/D
- Agitation
- Headache
- Sexual Dysfunction, decreased libido and difficulty reaching orgasm
- Headache
- Insomnia/ anxiety (during initial activation)
- Weight gain/ loss
- Serotonin syndrome (excess serotonin) - serious, life threatening
- High temperature
- Dystonia
- Diaphoresis
- sleepiness
- emotional flattening
What drug class do these drugs belong to?
Paroxetine (Paxil)
Escitalopram (Lexapro)
Fluoxetine (Prozac)
SSRI’s
What drug class do Chlordiazepoxide (Librium), Lorazepam (Ativan) belong to?
Benzodiazepine
Indications for Paroxetine (Paxil):
Generalized Anxiety Disorder, Panic disorder
Indications for Escitalopram (Lexapro):
Generalized Anxiety Disorder
Indications for Fluoxetine (Prozac):
Body Dysmorphic Disorder
Indications for Chlordiazepoxide (Librium):
alcohol withdrawal;
sedative, hypnotic or anxiolytic withdrawal
What are the indications for Lorazepam (Ativan)?
GAD, social phobia, alcohol withdrawal;
sedative, hypnotic, or anxiolytic withdrawal
What are the indications for Dolophine (Methadone)?
synthetic opiate like drug - for opioid dependence
is an: analgesic antidiarrheal antitussive used in substitution therapy
What are the side effects for Dolophine (Methadone)?
respiratory depression constipation fecal impaction hypotension decreased libido retarded ejaculation impotence orgasm failure
What are the indications for Naloxone (Narcan)?
opioid overdose b/c it is an opioid antagonist
What are the side effects for Naloxone (Narcan)?
increased HR HTN hypotension n/v tremor withdrawal sx diaphoresis pulmonary edema dyspnea
serious reactions:
ventricular fibrillation
cardiac arrest
seizures
What are the indications for Bupropion (Zyban) which inhibits the reuptake of norepi, serotonin, and dopamine?
nicotine use disorder (for smoking cessation)
comorbid depression and ADHD
major depression
What are the side effects for Bupoprion (Zyban) ?
headache dizziness insomnia sedation tachycardia hypertension dry mouth n/v weight gain or loss seizure constipation tremor
What are the indications for Buprenorphine?
opioid withdrawal
What are the side effects for Buprenorphine?
sedation headache insomnia pain (opioid dependency use) withdrawal sx (opioid dependency use) dizziness/vertigo diaphoresis nausea constipation rhinitis asthenia depression anxiety vasodilation hypotension hypoventilation
SSRI’s are first line agents for _ __ _. They take __-__ weeks to reach symptom control.
chronic anxiety disorders; 3-4
SSRI’s act on the __ system and indirectly on __
serotonin
GABA
Benzodiazepine Side effects
- Drowsiness
- Confusion
- Lethargy
- Tolerance
- Psychological and physical dependence
- Potentiates side effects of other CNS depressants (ETOH)
- May aggravate symptoms of depression
- Orthostatic hypotension
- Paradoxical excitement
- memory impairment
- motor incoordination
SSRI’s have shown some efficacy in decreasing impulsivity in __ __ __
borderline personality disorder
Benzodiazepines can be used for __ __ or __ __ disorder
sedative hypnotic
anxiolytic use
Buprenorphine is __ powerful than methadone but is considered to be somewhat __ and causes __ side effects
less
safer
fewer
