MEDS

Question 1

Side effects of SSRI’s

Answer 1

1. N/V/D
2. Agitation
3. Headache
4. Sexual Dysfunction, decreased libido and difficulty reaching orgasm
5. Headache
6. Insomnia/ anxiety (during initial activation)
7. Weight gain/ loss
8. Serotonin syndrome (excess serotonin) - serious, life threatening
9. High temperature
10. Dystonia
11. Diaphoresis
12. sleepiness
13. emotional flattening

Question 2

What drug class do these drugs belong to?

Paroxetine (Paxil)
Escitalopram (Lexapro)
Fluoxetine (Prozac)

Answer 2

SSRI’s

Question 3

What drug class do Chlordiazepoxide (Librium), Lorazepam (Ativan) belong to?

Answer 3

Benzodiazepine

Question 4

Indications for Paroxetine (Paxil):

Answer 4

Generalized Anxiety Disorder, Panic disorder

Question 5

Indications for Escitalopram (Lexapro):

Answer 5

Generalized Anxiety Disorder

Question 6

Indications for Fluoxetine (Prozac):

Answer 6

Body Dysmorphic Disorder

Question 7

Indications for Chlordiazepoxide (Librium):

Answer 7

alcohol withdrawal;

sedative, hypnotic or anxiolytic withdrawal

Question 8

What are the indications for Lorazepam (Ativan)?

Answer 8

GAD, social phobia, alcohol withdrawal;

sedative, hypnotic, or anxiolytic withdrawal

Question 9

What are the indications for Dolophine (Methadone)?

Answer 9

synthetic opiate like drug - for opioid dependence

is an: 
analgesic 
antidiarrheal
antitussive
used in substitution therapy

Question 10

What are the side effects for Dolophine (Methadone)?

Answer 10

respiratory depression
constipation
fecal impaction
hypotension
decreased libido
retarded ejaculation
impotence
orgasm failure

Question 11

What are the indications for Naloxone (Narcan)?

Answer 11

opioid overdose b/c it is an opioid antagonist

Question 12

What are the side effects for Naloxone (Narcan)?

Answer 12

increased HR 
HTN 
hypotension
n/v
tremor
withdrawal sx
diaphoresis
pulmonary edema 
dyspnea 

serious reactions:
ventricular fibrillation
cardiac arrest
seizures

Question 13

What are the indications for Bupropion (Zyban) which inhibits the reuptake of norepi, serotonin, and dopamine?

Answer 13

nicotine use disorder (for smoking cessation)

comorbid depression and ADHD

major depression

Question 14

What are the side effects for Bupoprion (Zyban) ?

Answer 14

headache 
dizziness
insomnia
sedation
tachycardia
hypertension
dry mouth 
n/v 
weight gain or loss
seizure
constipation
tremor

Question 15

What are the indications for Buprenorphine?

Answer 15

opioid withdrawal

Question 16

What are the side effects for Buprenorphine?

Answer 16

sedation 
headache 
insomnia
pain (opioid dependency use) 
withdrawal sx (opioid dependency use) 
dizziness/vertigo
diaphoresis
nausea
constipation
rhinitis 
asthenia
depression
anxiety
vasodilation
hypotension
hypoventilation

Question 17

SSRI’s are first line agents for _ __ _. They take __-__ weeks to reach symptom control.

Answer 17

chronic anxiety disorders; 3-4

Question 18

SSRI’s act on the __ system and indirectly on __

Answer 18

serotonin

GABA

Question 19

Benzodiazepine Side effects

Answer 19

1. Drowsiness
2. Confusion
3. Lethargy
4. Tolerance
5. Psychological and physical dependence
6. Potentiates side effects of other CNS depressants (ETOH)
7. May aggravate symptoms of depression
8. Orthostatic hypotension
9. Paradoxical excitement
10. memory impairment
11. motor incoordination

Question 20

SSRI’s have shown some efficacy in decreasing impulsivity in __ __ __

Answer 20

borderline personality disorder

Question 21

Benzodiazepines can be used for __ __ or __ __ disorder

Answer 21

sedative hypnotic

anxiolytic use

Question 22

Buprenorphine is __ powerful than methadone but is considered to be somewhat __ and causes __ side effects

Answer 22

less
safer
fewer