5 Bipolar Disorder Flashcards
Bipolar disorder is characterized by __ __ from profound __ to extreme __ with intervening periods of __.
mood swings
depression
euphoria
normalcy
Can delusions be present for someone with bipolar disorder?
YES
Onset of symptoms of bipolar disorder may have a __ __
seasonal pattern
What are the 5 bipolar disorder diagnoses?
- Bipolar I
- Bipolar II
- Cyclothymic Disorder
- Substance/Medication Induced Bipolar Disorder
- Bipolar Disorder due to another Medical Condition
Bipolar disorder affects ~ __ million or __% of adults in the US
- 7
2. 6
Is bipolar disorder more prevalent in women or men?
EQUALLY prevalent in both men and women
What is the average age of onset of bipolar disorder ?
early 20’s
Bipolar disorder tends to be recurrent following __ _ ___
first manic episode
Etiology
Bipolar Disorder is … (4)
- genetic
- biochemical
- neuroanatomical factors
- medication/drug induced
Genetic Factors Prevalence of bipolar disorder in the general population:
2.6%
Genetic Factors Prevalence of bipolar disorder in monozygotic twins:
60-80%
Genetic Factors Prevalence of bipolar disorder in dizygotic twins
10-20%
Genetic Factors Prevalence of bipolar disorder in child of 1 parent with bipolar disorder:
28%
Genetic Factors Prevalence of bipolar disorder in child of 2 parents with bipolar disorder
50-60%
Is there an excess or deficiency of DOPAMINE in:
A) Mania
B) Depression
A) Mania - EXCESS
B) Depression - DEFICIENCY
Is there an excess or deficiency of NOREPINEPHRINE in:
A) Mania
B) Depression
A) Mania - Excess
B) Depression - Deficiency
Is there an excessive or inadequate amount of CHOLINERGIC TRANSMISSION in:
A) Mania
B) Depression
A.) Mania - Inadequate
B.) Depression - Excessive
Neuroanatomical Factors for Bipolar Disorder:
__-sided lesions in: (4) areas
right
- limbic system
- temporobasal areas
- basal ganglia
- thalamus induced mania
Neuroanatomical Factors for Bipolar Disorder:
enlarged __ __
third ventricles
Neuroanatomical Factors for Bipolar Disorder:
__ __ __
subcortical white matter
Neuroanatomical Factors for Bipolar Disorder:
__ __
periventricular hyperintensities
Medications for bipolar disorder (4)
- steroids
- amphetamines
- antidepressants
- narcotics
Manic episode is defined as at least __ __ period of elevated, expansive or irritable mood
1 week
A manic episode causes __ __ , i.e. ____
marked impairment
hospitalization
manic episode is not attributable to __, ___, and __ __
substances
medications
medical conditions
What are 8 symptoms of a manic episode?
- inflated self-esteem/grandiosity
- decreased need for sleep
- talkative/pressured speech
- flight of ideas/racing thoughts
- distractibility
- increase in goal directed activity
- excessive involvement in activities with high potential for painful consequences
- agitation, irritability, aggression
A hypomanic episode is a __ day period of elevated, expansive, or irritable mood
4
A hypomanic episode is an episode where there is a __ in __
change in behavior
In a hypomanic episode, the disturbance in mood and change in functioning are…
observable by others
In a hypomanic episode, is it severe enough to cause marked impairment in functioning?
NO
A hypomanic episode is OR is not attributable to a substance/medication, medical condition?
IS NOT
Bipolar I and II Distinguishing Factors:
Manic Episode
A) Bipolar I
B) Bipolar II
A) Yes at least 1 week duration
B) NO
Bipolar I and II Distinguishing Factors:
Hypomanic Episode
A) Bipolar I
B) Bipolar II
A) n/a
B) Yes at least 4 days duration
Bipolar I and II Distinguishing Factors:
Major Depressive Episode
A) Bipolar I
B) Bipolar II
A) May be present and must be at least 2 weeks
B) Yes at least 2 weeks