Medicine in the Elderly* Flashcards
3 areas of implications of ageing population
- healthcare costs
- social/homecare costs
- economic
4 personality types of old people
- integrated: active, satisfied, flexible, functioning
- armouredL fights ageing, preoccupied with loss
- passive: dependent, low level of life satisfaction
- angry: low activity, low life satisfaction, bitter
4 skin changes
- wrinkles
- dry
- cambell de morgan spots
- seborrhoic keratosis
6 changes in mouth
- dec saliva production
- impaired mm mastication
- tooth loss
- decreased taste buds
- less sense of smell
- enlargement of tongue
21 other physiological changes
- less hepatic drug metabolism
- less GFR (Glomerular filtration rate) 50%
- prostate enlargement
- decreased bladder capacity
- bone loss
- thickening of valves AS
- dilation of large elastic arteries
- increased systolic BP
- reduced stroke volume/ CO
- decline in carviovascular stress response
- fall in forced vital capacity FVC and FEV1 forced expiratory volume
- reduced brain weight
- presbyacusis (hearing loss)
- hardening of lens (impaired near vision)
- flatter cornea (astigmatism)
- reduced lean body mass
- increase fat mass
- impaired ability to maintain body temp
- reduced oestrogen levels
- inc immune deficiency
4 IQ changes
- cross sectional studies suggest decline
- longitudinal studies suggest preserved
- verbal scores preserved
- tests requiring speed of response deteriorate
5 specific features of disease presentation
- non specific presentation
- atypical presentation
- multiple pathology
- symptoms attributed to old age
- single illness leading to catastrophic outcome
4 Is of non specific presentation
- Intellectual failure
- Incontinence
- Immobility
- Instability
3 atypical presentations
- myocardial infarction without chest pain (dyspnoea, confusion, hypotension)
- infection without inc WCC or temp
- silent perforation (eg stomach ulcers
6 symptoms erroneously attributed to old age
- hypothyroidism
- anaemia
- bowel problems
- urinary problems
- shortness of breath
- forgetfulness
8 single illness leading to catastrophic consequences
- pneumonia
- delirium
- postural instability
- fall
- fracture neck of femur
- immobility
- DVT/ PE
- death
5 physical signs of ageing
- small irregular pupils
- absent ankle reflexes
- reduced vibration sensation
- displaced apex (kyphoscoliosis)
- pulmonary crackles
drug reaction stats
5-15% of hospital admissions caused by adverse drug reactions
6-17% have adverse drug reactions in hospital
altered pharmacology with ageing 3
-less renal drug clearance
-variable changes to hepatic drug metabolism
-changes to volume of distribution
(use child doses)
change in volume of distribution 3
- more fat, less lean muscle
- lipid soluble drugs have inc volume of distribution –> prolonged effect eg diazepam
- water soluble drugs have smaller volume of distribution –> more rapid peak eg digoxin