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Year 3 Human Disease > Endocrine > Flashcards

Endocrine Flashcards

1
Q

location of pituitary gland

A

below hypothalamus in the brain

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2
Q

hormones produced in anterior pit gland

A 
TAGPL
TSH (--> thyroid gland, TH)
ACTH (--> adrenal gland, cortisol)
GH
Prolactin (lactation)
FSH/ LH (sex hormones)
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3
Q

4 categories of pituitary problems

A 
hormone overproduction (acromegaly, cushings, hyperthyroidism)
hormone deficiency
pressure effects 
systemic disease (infiltrative/ metastatic)
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4
Q

what surrounds pituitary gland and relevance

A

above (above hypothalamus): optic chiasm –> expansion of pit gland –> bilateral hemianopia
sides: cavernous sinus (inc carotid aa and cn 3,4,5 –> expansion of pit gland –> stroke/ tia, eye problems)

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5
Q

what mediates GH

A

IGF1

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6
Q

dental relevance of acromegaly

A

supraorbital ridges, macroglossia, interdental spacing, snoring, sleep apnoea

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7
Q

tx of acromegaly

A

gold standard: pituitary sugery

  • DA agonists
  • somatostatin analogues
  • GH R antagonists
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8
Q

dental relevance of cushingoid

A

poor wound healing, thin skin, easy bruising
psychiatric medications
immunocomp if on steroids

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Year 3 Human Disease (28 decks)

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