Medicine: Cardio Flashcards
How would you present a murmur?
HS 1+2+Added
When, where, insp/exp, radiation, at least grade three
Indicates, ddx, ECG/echo
Which murmurs get louder on insp/exp?
RILE
Right sided w Insp + Left sided w Exp
List the four classic murmurs you hear
AS - ESM - lub whoosh dub
AR - EDM - lub durrr
MS - MDM - rrrlub dub
MR - PSM - lub oof dub
NB: HOCM also ESM + ASD also MDM
Which is worse a longer or louder murmur?
Longer > Louder
What are the differentials of aortic stenosis? (2)
Aortic Sclerosis
Pulmonary Stenosis
NB: if it radiates to the carotids stenosis > sclerosis
If the pt has aortic sten what should you advise?
Any chest pain, feeling faint, SOB come back to us
NB: also in order of worsening risk of mortality angina, syncope, dyspnoea
How would you present an ECG?
Pt details, date and time, calibration, rate, rhythm, axis, pqrst, overall impression
How many seconds are the small and large squares?
Small - 0.04s
Large - 0.2s
How can you calculate rate from the rhythm strip?
- Number of complexes in 10s x6
2. Divide 300 by number of big squares b/w R waves
How can the rhythm be described? (3)
Sinus, AF, Block
The quick method of testing for axis deviation
Use leads I+II and if the R waves:
Point away - leaving - LEFT
Point together - reaching - RIGHT
And if lead III is more neg think left vs more pos think right
Which p wave shows which atrial hypertrophy?
Bifid P mitrale - left atrial hypertrophy eg mitral stenosis/regurg
Peaked P pulmonale - right atrial hypertrophy eg tricuspid stenosis/regurg
How long should the PR interval be?
0.12-0.2s ie 3-5 small squares
Outline the different degrees of AV heart block
1st: prolong PR interval
2nd: Mobitz 1 - prolongation then dropped QRS + Mobitz 2 - constant PR and often wide QRS w occ dropped QRS
3rd: complete dissociation b/w p waves and QRS complexes
Which heart block is also called Wenckebach?
2nd Degree Mobitz I
Which heart block is also called Hay?
2nd Degree Mobitz II
Which Mobitz type is more likely to degenerate into 3rd degree?
Type 1
How long should the QRS complex be?
<0.12s ie <3 small squares
What does a narrow QRS suggest?
SVT
What does a broad QRS suggest?
BBB, VT, VF, WPW
Which BBB is more concerning?
A new LBBB is always pathological whereas RBBB could be a normal variant
S1Q3T3
Rare sign of PE w deep S in I, pathological Q in III, inverted T in III
Anteroseptal MI Leads
V1-V4
Anteroseptal MI Artery
LAD
Lateral MI Leads
V5-V6, I, aVL
Lateral MI Artery
Left Circumflex
Anterolateral MI Leads
V4-V5, I, aVL
Anterolateral MI Arteries
LAD + Left Circumflex = Left Coronary
Inferior MI Leads
II, III, aVF
Inferior MI Artery
Right Coronary
What else does the right coronary artery supply?
SA + AV Nodes
Posterior MI Leads
Global ST depression w dominant R waves in V1-V2
Posterior MI Arteries
Left Circumflex + Right Coronary
Comps of LCA v RCA occlusion
LCA - left ventricular failure + pericarditis
RCA - rhythm abnormalities
Plus aneurysm + PE
Immediate mx of a STEMI
MONAT + PCI/Thrombolysis
Tx of Pericarditis
NSAIDs
Tx of Complete Heart Block
Pacemaker
What are the ECG changes of left ventricular aneurysm?
Persistent ST Elevation
What are the ECG changes of PE?
No Changes
Sinus Tachycardia
RV Strain
Inverted T Waves
S1Q3T3
What med should pts be on following MI or stroke life long?
Aspirin
What does a saddled ST segment suggest? (2)
Pericarditis
Tamponade
What does a reverse tick ST segment suggest?
Digoxin Toxicity
Which leads is where T wave inversion is normal?
III, aVR, V1
Tx of AF
Unstable: A-E + DCCV
Stable: look for treatable causes (structural, thyroid, clot, infection, K/Mg/Ca) + ultimate tx is to mx risk of HF due to tachy and risk of stroke due to clot in LA
Risk of HF: Rate (β-blocker/CCB and digoxin) + Rhythm (DCCV or flecainide/amiodarone if structural heart disease)
Risk of Stroke: Anticoag (CHA2DS2-VASc + HAS-BLED) - start DOAC or warfarin 2wks after
Why do you tx the rate component of AF w beta blockade > digoxin?
Beta blockade allows the HR to change w exercise
Which drugs should you NOT give to AF + WPW pts?
Verapamil + Digoxin
Risk of sudden cardiac death in young pts
When would flecainide NOT be first line rx for rhythm control in AF?
There’s an underlying structural heart disease
When do you do rhythm > rate control first line?
Reversible cause, new onset <48hrs, more suitable based on clinical judgement, HF primarily caused by AF
When do you refer AF to the cardiologist?
Rhythm control is appropriate, rate control tx fails to control sx, ECG: WPW/LQTS, echo: valvular disease
What are the signs of heart failure on CXR?
A - alveolar oedema B - Kerley B lines C - cardiomegaly D - dilated UL vessels E - pleural effusion
Which cardiac drugs can lead to gynaecomastia? (2)
Spironolactone + Digoxin
Which dysmorphic features suggest what cardiac disease?
Short stature: Turner (bicuspid aortic valve and coarctation), Noonan (pulm stenosis and HOCM), Down (AVSD, VSD, TOF)
Tall stature: Marfans (aortic regurg)
If the pulse is regularly regular, is the pulse sinus rhythm?
You can never tell if a pulse is sinus rhythm at the bedside unless you have an ECG w a p wave before every QRS complex
If the pulse is irregularly irregular, does the pt have AF?
Prbly but can’t say for sure w/o an ECG showing lack of p waves
Ddx: complete heart block and sinus rhythm w multiple ventricular ectopics
What are the four aspects of pulse? And where is volume measured?
Rate, Rhythm, Volume, Character
Rate + Rhythm - Radial
Volume + Character - Carotid
What is the carotid pulse like in AS?
Low volume and slow rising character
What are the causes of a RR delay? (2)
Coarctation of Aorta
Blalock-Taussig Shunt
What does a tapping apex beat always suggest?
Mitral Stenosis
What causes a hyperdynamic apex beat? (2)
Pressure Loaded - severe HTN, AS, HOCM - LV hypertrophy
Volume Loaded - MR and AR - LV dilatation
What causes an impalpable apex beat? (5)
DOPES
Dextrocardia Obesity Pericardial Effusion Emphysema Shock
Ddx of an ESM
Any systolic murmur but if specifically ejection systolic: aortic stenosis, aortic sclerosis, HOCM
Typical HOCM pt
PC: exertional lightheadedness +/- syncope
FHx: SCD in middle age
O/E: jerky carotid pulse, double apical impulse, ESM
What is the inheritance pattern of HOCM?
Autosomal Dominant
When does the ESM in HOCM pts get louder?
Valsalva
When does the ESM in HOCM pts get quieter?
Squatting
What is a/w HOCM?
WPW + Friedrich’s Ataxia
What is pathognomonic of HOCM on an echo?
Systolic anterior motion of the anterior mitral valve leaflet
Tx of HOCM
M: beta blockers and negatively inotropic CCB
S: ICD, myomectomy, alcohol septal ablation
The main causes of AS (2)
Younger - bicuspid aortic valve
Older - degenerative calcification
PLUS Rheumatic heart disease
What ausc gives away a bicuspid aortic valve?
Ejection systolic click
What usually coexists w bicuspid aortic valve?
Coarctation
Mx of AS
Sx or severe ie echo gradient >50mmHg = surgery
What is Heyde’s syndrome?
Angiodysplasia in aortic stenosis due to an acquired deficiency of vWF caused by areas of high shear stress
What is the definitive tx for Heyde’s syndrome?
AVR
Comps of valve replacement (5)
FIBAT
Failure Infection Bleeding Anaemia Thromboembolism
The main causes of AR (3)
Leaflets don’t work (endocarditis, bicuspid, HTN) or work but don’t meet in the middle (aortitis a/w syphilis and ank spond) and connective tissue disease
Eponymous signs of aortic regurg (5)
Quincke’s Sign: capillary pulsation in the nail beds
DeMusset’s Sign: head nodding w systole
Corrigan’s Sign: big neck pulses
Traube’s Sign: pistol shot femorals
Duroziez’s Sign: to and fro double murmur over femoral artery when pressure is applied distal to site of ausc
Sx and signs of severity in aortic regurg
Sx - angina + SOBOE
Signs - wide pulse pressure, displaced apex, CCF
Mx of AR
Acute - emerg surgery
Chronic - afterload reduction
NB: again like AS if sx or echo criteria (end systolic diameter >55mm, aortic root dilatation >50mm, ejection fraction <50%) consider valve replacement
What does polycythaemia inc your risk of? (2)
Gout + VTE
Which ventricle dilates in VSD?
Left because during diastole blood enters the LV from both the LA and RV
What are VSD pts at risk of?
Endocarditis
Tx of VSD
Percutaneous Amplatzer device insertion or open heart surgery
If a pt has a stroke following a DVT instead of a PE what does this elude to?
PFO + ASD
Which ASD is more common?
Secundum > Primum
Which murmur is heard if a pt has an ASD?
MDM + fixed split S2 that doesn’t change w respiration
What are ASD pts at risk of?
AF + Paradoxical Emboli
Ix for ASD
ECG RBBB + Bubble Echo
Which syndrome is TOF a/w?
DiGeorge 22q11
Ddx of a MDM
Anything that obstructs the mitral orifice: MS, LA thrombus, atrial myxoma, Carey-Coombs murmur (mitral valvulitis)
PLUS TS and Austin-Flint murmur (severe AR)
Typical mitral stenosis pt
PC: preg lady recurrently worsened SOBOE and orthopnea
PMHx: recurrent pharyngitis + AF
O/E: malar flush, low-normal BP, tapping apex beat, loud and palpable first HS, rumbling MDM
Causes of MS (2)
Rheumatic fever, abs to group A beta haemolytic strep, 2-3wks after pharyngitis
Carcinoid syndrome, right sided valvular stenosis due to elevated serotonin production, left sided valvular stenosis due to lung mets
Mx of MS (ECG + Rx)
ECG: AF +p mitrale in lead II
Rx: of the AF + valvuloplasty if valve leaflets pliable and uncalcified or closed/open valvotomy
Comps of MS (3)
AF
Pulm HTN -> cor pulmonale
LA enlargement -> Ortner’s syndrome
What is cor pulmonale?
Enlargement and failure of the RV due to pulm stenosis or pulm HTN
Why can you get a hoarse voice w mitral stenosis? And what syndrome is this called?
The LA enlargement compresses the recurrent laryngeal nerve resulting in Ortner’s syndrome
What is S1? LUB
Closure of mitral and tricuspid valves denoting the start of systole
What is S2? DUB
Closure of aortic and pulm valves denoting the start of diastole
What is S3? KEN-TU-CKY
Rapid ventricular filling: MR + HF
Normal/Abnormal
What is S4? TE-NNE-SSEE
The atrial contract against a stiff ventricle: AS + HTN
Always Abnormal
How is Rheumatic fever diagnosed?
ASOT
What are the Duckett-Jones criteria?
Require 2 major OR 1 major and 2 minor
Major: Carditis, migratory flitting polyArthritis, Sydenham’s chorea, Erythema marginatum, Subcutaneous nodules
Minor: raised ESR, raised WCC, prolonged PR interval, arthralgia, pyrexia, prev RF
How is Rheumatic fever treated?
High dose aspirin + penicillin V
NB: use clindamycin if penicillin allergic
What is Takotsubo’s cardiomyopathy?
A catecholamine mediated myocardial stunning resulting in transient LV impairment that will fully recover in ~1w
Typically presentation is chest discomfort and SOB in post menopausal woman following bout of emotional stress
No RFs, rise in trop and ant stemi on ECG, unobstructed coronaries on emerg angiogram
Do you get a trop rise in cardiac syndrome X?
No
What is the Vaughan Williams classification of anti-arrhythmic drugs?
Class I: sodium channel blockers - procainamide, lidocaine, flecainide
Class II: beta blockers - bisoprolol + propranolol
Class III: potassium channel blockers - amiodarone + sotalol
Class IV: calcium channel blockers - verapamil + diltiazem
What are the five types of MI?
I: impaired blood flow to myocardium, plaque rupture, revascularise
II: imbalance b/w O2 supply and demand, inc risk of VF and type I, tx underlying disease eg HR, BP, sepsis
III: MI resulting in death when biomarker values are unavailable
IV: MI related to PCI or stent thrombosis
V: MI related to CABG
What does prolonged ST elevation in several leads w/o Q waves in a young pt suggest?
Pericarditis
What are the ECG findings of WPW? (3)
Shortened PR interval, delta wave, prolonged QRS complex
What are the top cause of AF?
IHD + RHD
Plus reversible causes: thyrotoxicosis, PE, excess alcohol/caffeine
What are the CXR findings of a pt w mitral stenosis? (2)
Enlarged left atrium + scattered dense opacities
What are the doses in MONAT?
Diamorphine IV 2.5-5mg
Aspirin PO 300mg -> 75mg OD lifelong
Ticagrelor PO 180mg -> 90mg BD 12mnths
Comps of MI
FAM: failure (LCA), arrhythmias (RCA), murmurs (MR + VSD)
Plus: aneurysm, pericarditis, PE
What are the ECG findings of left ventricular aneurysm?
Persistent ST Elevation
What are the ECG findings of a PE?
Normal ECG
Sinus Tachycardia
Right Ventricular Strain
Inverted T waves in V1-4
S1Q3T3 + Right Axis Deviation
Tx of SVT
- Vagal stimulation: carotid sinus massage + valsalva manoeuvre
- Adenosine IV 6-12-12mg
- Monitor ECG continuously
What are the Jones criteria for acute rheumatic fever?
Evidence of recent group A strep infection plus two major or one major two minor
Major: carditis, arthritis, s/c nodules, erythema marginatum, sydenham’s chorea
Minor: prolonged PR interval, arthralgia, raised ESR, fever, hx of rheumatic fever
What valves problems are common in chronic rheumatic heart disease?
MS+AR
Ddx of ARF
Carditis: infective endocarditis, cardiomyopathy, Kawasaki disease
Arthritis: reactive, JIA, HSP
Erythema: multiforme, migrans, adverse drug reactions
Chorea: Wilson’s + Huntington’s
CHA2DS2-VASc
Congestive HF, HTN, age >74, diabetes, stroke, vasc disease, age 65-74, sex=female
What should you do if the CHA2DS2-VASc score is >=2?
Start pt on warfarin or DOAC
If the score is 1 for male consider and 1 for female none is needed
HAS-BLED
HTN, abnormal liver +/or renal function, stroke, bleeding hx, labile INR, elderly >65, drugs +/or alcohol
What should you do if the HAS-BLED score is >=3?
Alternatives to anticoag should be considered as pt is at high risk of major bleeding
Which rhythms are shockable?
VF + Pulseless VT
Which rhythms are non-shockable?
PEA + Asystole
What will the MRI show if alcoholic DCM is fully reversible?
No mid-wall fibrosis
When would you consider CRT in heart failure pts?
EF <35% + QRS >120ms
What BNP excludes heart failure in the acute setting?
<100ng/mL
What are other causes of a raised BNP?
Pulm HTN Pneumonia Pulm Embolus Renal Failure Sepsis
What are other causes of a raised troponin?
Infection
Inflammation
Malignancy
Which ECG lead colours go where?
Ride Your Green Bike: right arm red, left arm yellow, left leg green, right leg black
Where do you commonly find reciprocal ST depression in a STEMI?
The next letter along in PAILS: posterior, anterior, inferior, lateral, septal
What gives you a double impulse apex?
HCOM
What are the Brugada criteria used for?
VT vs SVT w Aberrancy
If there’s absence of an RS complex in all precordial leads, R-S >100ms in one precordial lead, AV dissociation or morphology criteria for VT in V1-2 and V6 then VT > SVT
Tx of Cardiac Tamponade
Pericardiocentesis
What affects the apex beat position?
YES - dilatation caused by volume overload: AR, MR, ASD/VSD
NO - concentric hypertrophy caused by pressure overload: AS, HTN, coarctation of aorta
What are the causes of a dominant R wave in leads V1-2?
PPRRDDWPW
Posterior MI PE RVH RBBB Dextrocardia Duchenne WPW
What are the causes of cardiomyopathy?
Hypertrophic: autosomal dominance inheritance
Restrictive: SHAPE - sarcoidosis, haemochromatosis, amyloidosis, primary endomyocardial fibrosis, endocarditis
Dilated: DILATE - dystrophy, infection, late preg, AI, toxins, endocrine
What are the Framingham criteria used for?
Dx of CCF: two major OR one major + two minor
What should you suspect if the creatinine starts shooting up after starting ACEi?
Renal Artery Stenosis
Which beta blocker has anti arrhythmic properties?
Sotalol
Why do we worry about non-sustained VT?
NSVT -> Sustained VT
Mx of Hyperlipidaemia
- Lifestyle
- Atorvastatin
- Ezetimibe
- Alirocumab
When should you stop statins? (2)
If inc CK >10 fold OR AST >100U/L
Ix for IE
Blood Cultures x3 + TOE
Plus: urinalysis, ECG, CXR
What axis deviation is seen in WPW syndrome?
Left
Which electrolyte abnormality can cause a long QT interval?
HypoK
Which drug in the tx of hypertension can cause angioedema?
ACEi
TdP
PVT + QT Prolongation
How are the precordial leads classified?
V1-2: Septal
V3-4: Anterior
V5-6: Lateral
What other leads would show changes in an anterolateral STEMI?
Maximal ST elevation in V3-6, I, aVL
Reciprocal ST depression in III + aVF
What would shock and a new systolic murmur suggest post-MI?
Development of VSD
Which meds are CI in a shocked pt?
Beta blockers + thrombolysis
Ddx of systolic murmur
AS PS HOCM ASD TOF
MR
TR
VSD
Mitral valve prolapse
Coarctation of the aorta
Ddx of diastolic murmur
AR
Graham-Steel
MS
Austin-Flint
Patent ductus arteriosus
Immediate mx of STEMI
Cardiac monitor, MONAT, PCI +/- stent
Which coronary artery is the culprit vessel for each territory?
Anterior + Lateral - LAD
Lateral + Posterior - LCX
Inferior - RCA
What does MONAT stand for?
IV Diamorphine 5mg
IV Metoclopramide 10mg
High Flow O2 if low sats
Sublingual GTN spray
PO Aspirin 300mg
PO Ticagrelor 180mg
What are the NICE guidelines for the secondary prevention of MI?
Aspirin 75mg OD
Ticagrelor 90mg BD
Ramipril up to 10mg OD
Bisoprolol up to 10mg OD
Atorvastatin 80mg OD
What is usually performed in pts prior to undergoing aortic valve replacement?
Trip to cathlab for a catheter coronary angiogram to establish any underlying ischaemia
Most common aetiology in young/old for AS
Young - Bicuspid
Older - Degenerative
What are the acute signs on CXR of pulm oedema?
The same as HF
How does mitral regurg often px?
Palps, SOB, fatigue
What are the clinical signs of MR?
Pansystolic murmur at the apex radiating to the axilla, displaced hyperdynamic apex, AF
What is mitral facies a/w?
Mitral Stenosis
Causes of sinus bradycardia (8)
Aerobic training, vagal stimulation, MI, beta blockers, hypothyroidism, hypothermia, raised ICP, infection
List three infections that cause bradycardia
Legionnaire’s disease, Lyme disease, typhoid fever
What is hypocalcaemia a/w?
Prolonged QT interval
What is the usual mode of death in HOCM?
Arrhythmia
Sx of HOCM
Asx OR
Angina
Dyspnoea
Syncope
Mx of HOCM
Beta blockers, CCBs, amiodarone - implantable defibrillator - surgery
What are CIs for thrombolysis?
AGAINST: aortic dissection, GI bleeding, allergic reaction prev, iatrogenic recent surgery, neuro stroke or malignancy, severe HTN, trauma
Ejection Systolic Murmurs
AS, PS, HOCM, ASD, TOF
Pansystolic Mumurs
MR, TR, VSD
Late Systolic Murmurs
Mitral valve prolapse + coarctation of the aorta
Early Diastolic Murmurs: ‘Blowing’
AR + Graham-Steel (PR)
Mid-Late Diastolic Murmurs: ‘Rumbling’
MS + Austin-Flint (AR)
Continuous Machine-Like Murmur
Patent ductus arteriosus
Tx of bradycardia
If shock, syncope, MI or HF commence IV atropine 500mcg
How many doses of atropine are given w no improvement before starting external pacing when tx bradycardia?
6
What is HOCM a/w? (2)
WPW + Friedrich’s Ataxia
What does the ECG of WPW look like?
Short PR (<120ms), wide QRS (>120ms), upsloping delta wave
What inc/dec the ESM in HOCM?
Inc - Valsalva + Dec - Squatting
What should you monitor before/during ACEi tx and what is acceptable?
Renal function w inc in creatinine up to 30% and electrolytes w inc in potassium up to 5.5mmol/L
ACEi SEs (4)
Cough
Angioedema
Hyperkalasmia
First dose hypotension
What are the variants of long QT syndrome?
LDT1 - exertional syncope
LQT2 - emotional stress
LQT3 - at night or rest
Name two congenital causes of a prolonged QT interval
Jervell-Lange-Nielsen (inc deafness) + Romano-Ward Syndrome (no deafness)
What abx classes can prolong the QT interval? (2)
Macrolides + Fluoroquinolones
Which electrolyte abnormalities can prolong the QT interval? (3)
HypoCa, HypoK, HypoMg
Mx of Aortic Dissection
A - ascending - control BP and surgery
B - descending - control BP
DeBakey Classification
Aortic Dissection:
I - originates in ascending aorta + propagates to at least the arch
II - originates in + is confined to the ascending aorta
III - originates in descending aorta + can extend distally>proximally
New onset AF w structural heart disease tx
Amiodarone
WPW Px
Tachy, Palps, Dizziness
FA Px
Weakness, poor coordination, hearing impairment
Bi/Trifascicular Blocks
Bi: RBBB + LAD
Tri: above + 1DHB
Buerger’s Disease Px
Young male smoker w intermittent claudication, ischaemic ulcers, superficial thrombophlebitis, Raynaud’s phenomenon
How does LQTS commonly px?
Young person w cardiac syncope, palps, tachyarrhythmias, arrest
Tx for massive PE + hypotension
Thrombolyse
HF Drug Mx
- ACEi + β-blocker
- Aldosterone Ant
PLUS one off pneumoococcal and annual influenza vaccines
When should you commence anticoag for a pt w AF + acute stroke? Why?
2wks after due to the risk of haemorrhagic transformation
When would you surg tx aortic stenosis?
One of: symptomatic, gradient >40mmHg and LV systolic dysfunction, coexisting CVD
When is balloon valvuloplasty performed in pts for aortic stenosis?
If critical and not fit for valve replacement
What are the stages of HTN?
- Clinic >140/90 and subsequent ABPM/HBPM avg >135/85
- Clinic >160/100 and subsequent ABPM/HBPM >150/95
- Clinic SBP >180 or DBP >110
Mx of HTN
Confirm dx w subsequent ABPM or HBPM readings
Identify and tx any RFs w lifestyle modifications and cause eg renal failure and hypothyroidism
Drug tx depending on their age, ethnicity, diabetes status: <55 or T2DM vs >55 or Afro Caribbean
If they reach step 4 the drug choice depends on if K above/below 4.5mmol/L
Regular monitoring for efficacy and SEs
When is oxygen given to pts in the initial mx of ACS?
<94%
What are the STEMI criteria?
Clinical sx w >20mins ECG features: 2.5mm in V2-3 men <40yo, 2.0mm in V2-3 men >40yo, 1.5mm in V2-3 women, 1.0mm in other leads, new LBBB
Mx of STEMI
Identify + Aspirin 300mg
If PCI possible within 120mins give praugrel + PCI
If PCI not possible within 120mins give antithrombin + fibrinolysis then repeat ECG @ 60-90mins
Mx of NSTEMI + Unstable Angina
Identify + Aspirin 300mg
If no immediate PCI planned give fondaparinux
If GRACE score high risk offer PCI within 72hrs and give antipl + unfractionated heparin
If GRACE score low risk give ticagrelor
What med changes should you make in mx of ACS if pt is at high risk of bleeding or already on oral anticoags?
Swap praugrel/ticagrelor for clopidogrel
What are the features of Buerger’s disease?
Strongly a/w smoking
Extremity ischaemia, superficial thrombophlebitis, Raynaud’s phenomenon
What is the adrenaline dose for cardiac arrest?
IV 1mg given as 10mls of 1:10,000 solution + followed by 20mls of 0.9% NaCl
What is the adrenaline dose for anaphylaxis?
IM 0.5mg given as 0.5mls of 1:1,000 solution
What is HOCM a/w? (2)
Friedreich’s Ataxia + WPW
What are the echo findings in HOCM? (3)
MR SAM ASH
Mitral Regurg
Systolic Ant Motion
Asymmetric Hypertrophy
Ddx of ST Elevation
MI, pericarditis, high take off, LV aneurysm, Prinzmetal’s angina
What are the common causes of IE?
Strep viridans, staph aureus (IVDU), staph epidermidis (prosthetic valves)
Comps of MI
Immediate: VF, VT, heart block
Early: rupture of septum -> cardiogenic shock, papillary muscle -> acute MR, free wall -> tamponade
Late: LV aneurysm -> stroke, chronic HF, pericarditis
Why should a beta blocker NOT be co presc w verapamil?
Risk of complete heart block
What can be done to red the risk of nitrate tolerance on standard release?
Use an asymmetric dosing interval to maintain a daily nitrate free time of 10-14hrs
What are the BP targets for T1DM and T2DM?
T1: <135/85
T2: <140/90