Medicine and Drugs: Developing Drugs Flashcards
1
Q
What should a new medicine be?
A
- effective to cure/ relieve
- safe (non-toxic)
- stable
2
Q
Stages of Developing Medicine
A
- lab tests
- animal tests
- clinical trials
3
Q
what do the lab tests use?
A
- cells (in vitro screening)
- tissue culture
- organs
4
Q
what are they looking for in animal test?
A
- toxicity
- dosage
5
Q
stages of clinicasl trials
A
- healthy people (side effects)
- ill people (dosage / effectiveness)
- placebos/ double blind trials
6
Q
What was the intended use of thalidomide?
A
sleeping pill
7
Q
What was it discovered to be effective for?
A
morning sickness in pregnant women
8
Q
What was the consequence of not testing thalidomide for morning sickness?
A
babies with limb deformities
9
Q
What happened after these consequences?
A
- drug was banned
- more rigorous procedures introduced
10
Q
What is thalidomide used for now?
A
- leprosy
- other diseases (cancers)
