Medications for Osteoporosis Flashcards
what sort of calcium supplement should be avoided
calcium from oyster shell or bone has a greater risk of carrying lead or other heavy metals
How does magnesium help in osteoporosis
it aids in diminishing bone loss when taken with Calcium and vitamin D
What is protos
a drug form of strontium approved for use in Europe for treating osteoporosis
What drug class is Alendronate (fosamax)
bisphosphonate
What is a weird part of the PARQ for alendronate
you must remain upright for at least 30 minutes after taking it due to esophageal irritation
What are side effects of alendronate (fosamax)
Osteonecrosis, atypical femur fractures, myalgias
What is the MOA of Bisphosphonate drugs
inhibit osteoclast activity
What drug class is Raloxifene (Evista)
SERM
What drug class is Teriparatide
synthetic PTH analogue, made from selected amino acids found in parathyroid hormone
What is the goal for SERMs (selective estrogen receptor modulator)
producing the same benefits that estrogen has on bone density and on lowering cholesterol levels without increasing the risk for hormone-related cancers
What is the MOA of Raloxifene
Binding to select estrogen receptor sites. This drug developed to maintain beneficial estrogenic activity on bone and lipids and “anti-estrogenic” activity on endometrial and breast tissue
What is a side effect of Raloxifene
increased DVT and clot risk.
How is calcitonin administered
Nasal spray
What is the MOA of calcitonin
Osteoclast inhibition
What is calcitonin approved to treat
osteoporosis, NOT for osteopenia or prevention
