Medications for GERD and PUD

Question 1

Describe the 4 general pharmacologic approaches for GERD and PUD

Answer 1

Antacids – neutralize acid

Antisecretory agents – prevent acid from being produced or prevent stimulation of acid production (H2 receptor antagonists, PPIs)

Mucosal protectants – coat/protect gastric mucosa

Antimicrobials – treat H. pylori infection

Question 2

What are some lifestyle modifications for GERD?

Answer 2

Elevate the head of the bed // avoid sleeping on your back

Dietary changes (avoid foods, eat smaller meals, avoid eating within 3 hours of laying down)

Weight reduction

Smoking cessation

Avoid tight-fitting clothing

Discontinue or use meds that exacerbate GERD with caution