Medication dosage ranges Flashcards
What is the dose of oral AMIODARONE?
Loading dose (which may be required in urgent cases):
200mg TDS for 1 week, then
200mg BD for 1 week.
Maintenance dose:
100-200mg once daily
(400mg may be required for ventricular arrhythmias)
What is the dose of colchicine for an acute gout flare?
TWO tablets (=1mg) stat and then ONE tablet (=500mcg) ONE hour later.
Do not repeat the course within the three days.
What is the childrens dose for amoxicillin?
15-25mg/kg (MAX 500mg) every EIGHT hours.
For severe infections can be 800mg tds.
What is the interval of changing a buprenorphine patch?
Change patch every SEVEN days
What starting strength of buprenorphine patch should be used in an opioid naive patient? And at what dosing interval should titration occur?
5mcg to a maximum of 40mcg, with increase intervals done at no less than 3 days
What is dose of Aspalgin (aspirin with codeine) and max daily dose?
1-2 q4h prn *M8
What is the dose of conventional oral morphine for acute pain in an adult and child weighing over 50kg?
5-15mg every 4 hours
(Start with 5mg in patients over 70)
If patient weighs less than 50kg and is opioid naive, start with 2.5-5mg.
What is the formula for calculating the dose for breakthrough pain when a patient is taking controlled release morphine?
ONE SIXTH of total daily dose
(If repeated breakthrough doses are required, adjust the regular baseline morphine dose)
What is the formula to convert a patient to controlled release morphine after taking conventional morphine?
Calculate the total conventional dose over 24 hours, for MS contin brand give half the total daily dose every 12 hours.
What is the dose of morphine for chronic non-cancer pain?
5-20mg BD, review every 1-2 weeks
What is the tapering dose of morphine?
Short term exposure: reduce by 10-25% each week
Longer term exposure (years): reduce by 10-25% each month
Which opioids are partial agonists and what does this mean?
Buprenorphine
Tramadol
They have a ceiling response and therefore an increase in dose will not produce additional effect
Which brand of controlled release morphine is given once daily?
MS mono
Which brand of controlled release morphine can be both one or twice daily dosing?
Kapanol
Which brand of controlled release morphine has twice daily dosing ONLY?
MS contin
What is the usual and maximum dose of oxycodone in acute pain and palliative care?
5-15mg of conventional product q4h
Those over the age of 70 should be started on 5mg.
There is no maximum dose, only adverse effects limit the dose.
What is the children’s dose of conventional oxycodone?
0.1mg-0.2mg/kg (MAX 5MG) every 4-6 hours.
What is the maximum daily dose of controlled release tapentadol?
500mg daily total.
At what interval should tapentadol be titrated at?
Dose can be increased by 50mg BD every THREE days if required.
What is the dosage range of conventional tapentadol?
Start with 50mg every 4-6 hours
(A second 50mg dose can be taken after the first hour if needed)
Usual maintenance dose is 50-100mg every 4-6 hours.
Maximum = 600mg (except on day one = 700mg)
What is the normal dose and maximum dose of tramadol?
50-100mg every 4-6 hours
Maximum =400mg daily (except if >75 years =300mg daily)
How can you tell by a prescription for the antiviral medications; famciclovir, aciclovir and valaciclovir what condition they are treating?
Duration and dose….
What is the duration of UTI antibiotic treatment for a female versus a male?
3-5 days for a female and 7 days for a male
What is the normal dosage range of clindamycin?
150-450mg every 6-8 hours
If given a prescription for valaciclovir 1g TDS f7d, what is the most likely indication?
Shingles
If given a prescription for valaciclovir 500mg BD for 5-10 days, what is the most likely indication?
Genital herpes treatment
A shorter course of 3 days would be indicated for recurrent infection
If given a prescription for valaciclovir 500mg once daily, what is the most likely indication?
Prevention of treatment or to reduce transmission to partner.
What is the dose of famciclovir to treat an initial genital herpes infection?
250mg TDS for 5-10 days
What is the maximum dose of a single injection of insulin?
80 units
Is insulin glargine 100 units and insulin glargine 300 units interchangeable?
NO - dose must be re titrated.
How should a lamotrigine dose be altered during and after pregnancy?
The dose should be increased during pregnancy, and decreased after birth.
Which of the anti-thyroid medications has a longer duration of action and therefore can be dosed once daily for maintenance?
Carbimazole
What is the maximum daily dose of allopurinol?
900mg
What is the dose of colchicine for ULT prophylaxis? and how does the dose change if the pt experiences a flare?
1 (500mcg) tablet once or twice daily, according to response and GI symptoms.
If pt experiences a flare, they should have TWO tablets and then ONE tablet ONE hour later. They should not repeat this course within three days but they should have resume their prophylaxis treatment after 12 hours.
What is the maximum daily dose of diclofenac?
200mg
What is the maximum daily dose of rizatriptan?
30mg daily.
What is the maximum daily dose of sumatriptan?
300mg daily.
What is the usual dosage range of baclofen?
10-25mg TDS.
What is the maximum dose of domperidone?
30mg daily
What is the maximum dose of phentermine and what is its usual treatment duration?
40mg daily
Short term treatment is recommended - up to 12 weeks
