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2020 CSO Exam > Medication > Flashcards

Medication Flashcards

1
Q

Mirtazipine

A

Remeron, for depression and appetite, chemo related nausea

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2
Q

Movantik (naloxegol)

A

Used for chronic opioid induced constipation

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3
Q

Nivolumab (Opdivo)

A

IV- immunotherapy, 2x/wk, targeted cell therapy, monoclonal antibody drugs

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4
Q

Capetecabine (xeloda)

A

Met breast cancer, colon and rectal cancer

Antineoplastic chemotherapy

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5
Q

Sitravatinib

A

Molecular inhibitor of tyrosine kinase - experimental drug

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6
Q

Etoposide

A

Chemo for lymphoma

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7
Q

Chemo: cell cycle non specific- alkylating agents

A

stops DNA replication- highly emetogenic

Carboplatin, cisplatin, cyclophasphamide, dacarbazine, oxaliplatin, temozolomide

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8
Q

Chemo: cell cycle specific- antimetabolites

A

Stop DNA synthesis by acting like false metabolites

Capecitabine, fluorouracil (5-FU), gemcitabine methotrexate

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9
Q

Chemo: cell cycle specific-antitumor antibiotics

A

inhibits cell division by binding to DNA

Bleomycin,

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10
Q

Chemo: cell cycle specific- antitumor antibiotics anthracyclines

A

doxorubicin anthracyclines inhibits cell division by binding to DNA

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11
Q

Chemo: cell cycle specific-epipodophylltoxins

A

damages cells before mitosis

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12
Q

Chemo: cell cycle specific-taxanes

A

mitosis phase of cell taxol doxtaxel

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13
Q

Chemo: cell cycle specific-vinca alkaloids

A

disrupt spindle formation- vincristine

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14
Q

Chemo: cell cycle specific- monoclonal antibodies

A

target Her2 (trastauzamab herceptin) EGFR (cetuximab) RANKL

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15
Q

Biotherapy: monoclonal antibodies

A

activate pathways cause apoptosis

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16
Q

biotherapy: protein targeted therapy

A

interact with target proteins inside cells

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17
Q

biotherapy: angiogenesis inhibitors

A

bevacizumab (avastin) targets VEGF

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18
Q

biotherapy: cytokines

A

interleukin 2 or interferon

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19
Q

biotherapy: cancer vaccines

A

hpv vaccine

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20
Q

biotherapy: radiopharmaceuticals

A

nuclear medicine

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21
Q

hormone therapy: tamoxifen

A

(SERM)

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22
Q

hormone therapy: aromatase inhibitors

23
Q

Hormone therapy

24
Q

Alimta

A

350-1000 mcg folic acid and B12 injections

25
Q

Cisplatin

A

highly emetogenic: delayed n/v: omega 3 and turmeric may increase benefit

hydration important

26
Q

carboplatin

A

highly emetogenic - delayed n/v

27
Q

cyclophosphamide

A

3L water/day empty bladder 2-3x even at night

28
Q

capecitabine (xeloda)

A

give with food and water, B6 (50-100 mg 2-3x/day may help hand foot syndrome)

29
Q

cetuximab (erbitux)

A

magnesium and calcium could ddrop

30
Q

Doxorubicin

A

omega 3, theanine, coq10 may benefit

31
Q

gemcitabine

32
Q

ifosfamide

33
Q

fluorouracil

A

damages GI tract, melt ice chips ac/pc chemo to decrease muscositis, B6 to reduce hand foot syndrome

34
Q

MTX

A

mouth sores and diarrhea likely- no multis with folic acid, damages GI tract, no alcohol

35
Q

cytarabine

36
Q

camptosar

A

diarrhea that can be treated with atropine, damages GI tract, omega 3 may reduce toxicity

37
Q

oxaliplatin (eloxatin)

A

sensitive to cold; B6 for hand foot syndrome

38
Q

Paclitaxel

A

omega 3 may reduce toxicity

39
Q

procarbazine

A

avoid foods high in tyramine for 2 weeks after, avoid caffeine and alcohol

40
Q

Tamoxifen

A

avoid antacids within 2 hrs, avoid CYP3a4 inducers (st johns wort, phenobarbital) and inhibitors (grapefruit juice, erythromycin)

inhibitors increase drug action while inducers decrease

41
Q

velcade

A

green tea makes less effective

42
Q

zanosar (streptozocin)

A

alters glucose metabolism in patients

43
Q

zometa (zoledronic acid)

A

500 mg calcium and 400 IU vit D

44
Q

tamoxifen

A

melatonin may increase response

45
Q

N/v meds prescribed

A

reglan (metoclopramide) dexamethasone, zofran, aprepitant NK1 receptor agonist

46
Q

atropine helps diarrhea from what

A

irinotecan

47
Q

colace

48
Q

dulcolax

A

bisacodyl irritates and stimulates

49
Q

senna

A

irritates and sstimulates

50
Q

immodium

A

loperamide can help with diarrhea from irinotecan (inhibits peristalsis)

51
Q

metamucil

A

bulks then stimulates peristalsis

52
Q

miralax

A

osmotic causes peristalsis

53
Q

MOM

A

draws waters and stimulate peristalsis

54
Q

Mg Citrate

A

draws water and stimulates peristalsis

2020 CSO Exam (32 decks)

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