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2020 CSO Exam > From Quizlet > Flashcards

From Quizlet Flashcards

1
Q

Limit MCT oil to __ mL/day

A

100 mL/day (6.5 tbsp or 760 kcal)

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2
Q

macrobiotic diet does not include

A

mango pineapple and papaya

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3
Q

zoledronic acid (zometa) is used for what

A

bone mets

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4
Q

zoledronic acid should be given with what vitamins

A

500 mg calcium, 400 IU vit D

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5
Q

St Johns Wort increases/decreases activity of vinblastine (velban) and vincristine (oncovin)

A

decreases by inducing cyt P4503A4 (CYP3a4): found in liver and intestine oxidizes xenobiotics like toxins or drugs to they can be removed from the body

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6
Q

grapefruit juice can increase a drugs activity by inhibiting enzyme responsible for drugs metabolism. what is one example of this

A

grapefruit juice and docetaxel resulted in reduced clearance by 15%

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7
Q

3-4 foods that can alter CYP3a4 (and thus alters drugs efficacy/toxicity)

A

pomegranate, grapefruit, star fruit, seville oranges citrus juicecs

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8
Q

5 supplements that affect Cyp3a enzymes

A

St Johns Wort, Black cohosh, ginseng, gingo bilboa, goldenseal

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9
Q

which drug causes pharyngolaryngeal dysesthesia

A

(cold feeling) oxaliplatin (eloxatin)

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10
Q

high vomiting chemos

A

cyclophosphamide H, doxorubicin M, cisplatin H, ifosfamide M, mechlorethamine H, carmustine H dacarbazine H

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11
Q

streptozotocin (zanosar) can alter what metabolism

A

glucose- hypoglycemia

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12
Q

what should women not take within 2 hrs of tamoxifin

A

antacids

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13
Q

on EN hyponatremia may be caused by overhydration, GI sodium losses and what

A

SIADH

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14
Q

2 types of targeted therapy

A

monoclonal antibodies, small-molucule drugs (end in mab)

  • these work by targeting proteins or genes the help stop cancer from growing or spreading
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15
Q

leucovorin (reduced form of folic acid) is given to decrease side effects of methotrexate but is also given with fluorouracil which does what

A

makes side effects more severe

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16
Q

what drug is used as an antidote for chemotherapy

A

uridine triacetate (vistogard)

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17
Q

cytokines

A

protein mediators produced by inflammatory cells which signal metabolic changes

  • those related to cancer cachexia = cachectic, TNF, interleukin 1,6, interferon
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18
Q

tumor necrosis factor

A

hormone like protein that releases fat from fat stores reduces the concentration of enzymes required for the production and storage of fat and induces stage of anorexia

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19
Q

veno-occlusive disease

A

is sinusoidal obstruction system

20
Q

macrobiotic diet

A

no nightshade veggies (avoid animal products and dairy -processed food)

21
Q

to decrease acute vomiting (within 24 hours of chemo) these 3 drugs are often given before chemo

A

ondansetron (serotonin receptor agonist), dexamethasone (steroid), aprepitant (NK1 receptor agonost)

22
Q

5ht3 receptor agonist

A

ondansetron

23
Q

anticipatory n/v can be helped with

A

ativan

24
Q

T/F mucositis is just inflammation of mouth and esophagus

A

F inflammation of mucous membrane lining of GI tract (mouth to butthole)

25
Q

which chemo causes damage to GI tract

A

5-FU and methotrexate

26
Q

steroid side effects

A

osteoporosis, fluid retention, adrenal suppression, glucose intolerance, lyte imbalance, muscle wasting

27
Q

when boney mets for breast lung and pancreases occur hypercalemia can also occur, should you reduce calcium in diet?

A

no

28
Q

energy needs for children HCT

A

initial: 1.6-1.8 x BMR and maintenance 1.4-1.6 x BMR

29
Q

how many mL of MCT should someone start with

A

15mL (no more than 20 mL at a time)

30
Q

Physical activity most proven in which cancers

A

Breast colon endometrial and lung

31
Q

Serum magnesium can drop with which chemos

A

Cyclosporine, oxaliplatin, cetuximab, panitumab

32
Q

Pet scan

A

Radioactive glucose

33
Q

Indirect calorimetry measures what

A

RMR

34
Q

HCT kcal needs for adults

A

30-35

35
Q

Pro for cancer , hct , short bowel , IBD

A

1.0-1.5, 1.5, 1.5-2.0, 1.0-1.5

36
Q

SIADH can cause what nutrition related

A

Over hydration

37
Q

RDa for vit

A 
Calc 1000-1200 - 2500
Iron 8, 18 - 45
Phos 700 - 4000
Zinc 11 and 8 - 40
Vit A 900-700 -2800
Folate 400 -1000
B12 2.4 - 
Vit C 90 and 75 - 2000
Vit D 15 and 20 - 100
Vit E 15 - 1000
38
Q

Mnt for thrombocytopenia

A

Overly rough or course foods to avoid cut bleeding

39
Q

Anemia

A

Many reasons but some could be iron folate and b12 deficiency

40
Q

Anemia labs what do they mean
Hgb

Serum ferritin
Serum iron 
tibc 
Transferrin sat 
RDW
MCV
A

Hgb says if there is anemia < 8 very high

Iron deficiency 
Low serum ferritin 
Low serum iron
High TIBC
Low transferrin
High RDW
Low MCV
B12 deficiency 
High MCV 
Low serum b12
High serum mma 
High hcy (also b6)

Folate deficiency
High MCV
Low B12
Low rbc and serum folate (fluctuate with oral intake)

41
Q

What could potentially help with PN in HCT

A

Glutamine .2-.5 g/kg/day

42
Q

HCT how much fat

A

25-30% of kcal

43
Q

Potentially beneficial supplements for peripheral neuropathy

A

Vit E, calcium, mg, glutamine, glutathione, acetyl L carnitine

44
Q

EPA is useful for malnutrition how much

A

.26-6.0 g per day no pancreas

45
Q

Head and neck cancer which vitamin could increase cancer risk again

A

Vit e more than 400 iu

46
Q

Improve taste with what vit

A

50 mg elemental zinc less than 60 days

47
Q

What nectar can help with thickened saliva

A

Papaya

2020 CSO Exam (32 decks)

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