Medical Marijuana For Pain

Question 1

The main psychoactive component of marijuana and is highly lipophilic.

Answer 1

Delta 9 -THC

Question 2

What components is medical marijuana characterized by?

Answer 2

1) THC content

2) Cannabidiol content

Question 3

Non-psychoactive part of marijuana that has be used to treat seizures.

Answer 3

Cannabidiol

Question 4

Dravat’s Syndrome

Answer 4

Rare form of childhood epilepsy in which cannabidiol can be used to treat.

Question 5

This is now a qualifying condition for medical marijuana use.

Answer 5

Chronic pain

Question 6

How do cannabinoids (marijuana) interact with opioids?

Answer 6

Prolong the effect of opioids.

Question 7

What percent of marijuana users become addicted to it?

Answer 7

9%.

Question 8

The biggest side effect in trying to stop marijuana.

Answer 8

Difficulty sleeping.

Question 9

The types of cannabinoid receptors in the body and their location.

Answer 9

CB1 = CNS

CB2= PNS

Question 10

The most abundant GPCR in the brain.

Answer 10

CB1

Question 11

Endocannabinoids

Answer 11

2-AG

Anandamide

Question 12

Cannabinoid ligands are lipopihilic or lipophobic?

Answer 12

Lipophilic

Question 13

Where is unmetabolized THC stored?

Answer 13

Fat cells

Can remain in the body up to 3 months.

Question 14

Type of neurotransmission in cannabinoids.

Answer 14

RETROGRADE

Question 15

NT’s released in cannabinoid neurotransmission.

Answer 15

GABA, Glutamate, Dopamine

Question 16

Steps in cannabinoid neurotransmission.

Answer 16

1) NT released (Dopamine, GABA, Glutamate) from pre-synaptic neuron.
2) Endocannabinoids (2-AG and Anandimide) released from the post-synaptic neuron.
3) Inhibit further NT release from the pre-synaptic neuron.

Question 17

Breaks down 2-AG

Answer 17

MAGL

Question 18

Breaks down Anandimide

Answer 18

FAAH

Question 19

Opioids and cannabinoids _______.

Answer 19

synergize.

Question 20

Benefit of taking opioids and cannabinoids together.

Answer 20

Cannabinoids are effective in pain relief.

Can be used in conjunction with opioids to relieve pain, thus needing less opioid dose (less dependence).

Question 21

T/F: Prescribed opiates may have a much larger than anticipated effect when taken with cannabinoids.

Answer 21

True

Question 22

What kind of pain can cannabinoids (medical marijuana) treat?

Answer 22

Acute, neuropathic, and inflammatory.

Question 23

Effects of marijuana.

Answer 23

Disrupts learning and memory.

Decreased connectivity between brain regions in learning and memory.

Decreased IQ.

Respiratory issues

Question 24

Effects of Marijuana on oral health.

Answer 24

Xerostomia
Decay
Leukoedema
Gingivitis
Alveolar bone loss
Increased prevalence of candida.

Question 25

T/F: Frequency recreational cannabis use is associated with deeper perio pockets, more clinical attachment loss, and higher odds of having severe periodontitis.

Answer 25

True

Question 26

You can get _________ from consistently smoking marijuana.

Answer 26

Hyperemesis

Question 27

Most terrible thing about synthetic marijuana.

Answer 27

Strong dependence