MedEd Flashcards
A 26 year old unconscious man is brought into A&E having been found lying alone on the street with needles next to him. The patient’s GCS = 11, RR = 10, BP = 97/65 mmHg and has pinpoint pupils. This patient likely has: Alcohol toxicity Aspirin overdose Opiate overdose Paracetamol overdose Warfarin toxicity
Opiate overdose
A 26 year old unconscious man is brought into A&E having been found lying alone on the street with needles next to him. The patient’s GCS = 11, RR = 10, BP = 97/65 mmHg and has pinpoint pupils. The most appropriate treatment is: IV naltrexone IV naloxone Mechanical Ventilation IV N-Acetyl-Cysteine IV Sodium Bicarbonate
IV naloxone
A 25 year old man is rushed to A&E after presenting with vomiting, hyperventilation and ringing in his ears. ABG shows a respiratory alkalosis.
The most likely cause of his presentation is:
Alcohol toxicity
Aspirin Overdose
Opiate Overdose
Paracetamol Overdose
Warfarin toxicity
Aspirin Overdose
what are different types of opiates
heroin
morphine
codeine
what are risk factors for opiate overdose
IVDU
patients in chronic pain
what is the triad of features in opiate overdose
CNS depression (coma) Respiratory depression Pinpoint pupils
what might patients with opiate overdose have (to do with bowel movements)
constipation
what is used for investigation and management of opiate overdose
IV naloxone
what are associations or risk factors for aspirin overdose
suicide attempts
accidents in children
what are features of aspirin overdose
hyperventilaiton
tinnitus
vomiting
sweating
what are investigations for aspirin overdose
salicyclate levels
ABG
-respiratory alkalosis (early due to hyperventilation)
-metabolic acidosis (late)
what are associations or risk factors with paracetamol overdose
chronic alcohol use (enzyme inducer)
intentional self harm
what are features of paracetamol overdose
asymptomatic - 1st 24hrs
then acute liver failure
-abdominal pain, vomiting, confusion (encephalopathy)
what investigations are completed in paracetamol overdose
paracetamol levels at 4hours post ingestion
ABG for acidosis
when are paracetamol levels at their highest in the plasma
4hours post ingestion
what is the management for paracetamol overdose
IV N-acetyl cysteine
what are features of digoxin overdose
xanthopsia (yellow-green halos)
arrhythmias
hypokalaemia
N+V
what are features of iron overdose
D+V
liver failure
drowsiness + coma
what can causes of hyponatraemia be split into
hypovolaemia
euvolaemia
hypervolaemia
what are hypovolaemic causes of hyponatraemia
- D+V
- diuretics
what are euvolaemic causes of hyponatraemia
- hypothyroidism
- adrenal insufficiency
- SIADH
what are hypervolaemic causes of hyponatraemia
- HF
- cirrhosis
- nephrotic syndrome
how is hyponatraemia caused by diuretics investigated
measure low urine sodium
what is the first line investigation for hyponatraemia
short synacthen test
what is the management for hypovolaemic hyponatraemia
volume replacement with 0.9% saline
stop diuretics
what is the management for euvolaemic hyponatramia
fluid restriction
treat cause
what is the management for hypervolaemic hyponatraemia
fluid restriction
treat cause