MedEd Flashcards

1
Q
1.  Andromeda, a 32 year old female presents with recurrent headaches. They are severe, on the right side of her head and often continue for the rest of the day.  Before the headaches start she gets tingling in her arms,  and when the headaches start she goes to bed. She is worried they might affect her relationship with her new boyfriend. 
a Cluster headache
b Intracranial space-occupying lesion
c Medication overuse
d Migraine
e Tension headache
A

migraine

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2
Q
2.  Homer, a 45 year old male has had excruciating headaches for the last month. He gets them about 5 times a week and notices his eyes watering. He had a similar episode 6 months ago. They are very disruptive to his poetry.
a Cluster headache
b Intracranial space-occupying lesion
c Migraine
d Subarachnoid haemorrhage
e Meningitis
A

cluster headache

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3
Q
3.  Atalanta, a 27 year old female athlete presents to the GP with early morning nausea and headaches which has been happening for at least a week.  Both are worst when she wakes up and improve throughout the day. She notes that she has been getting tired over the last few weeks, she is late on her period, and is definitely more irritable with her boyfriend, who despite being an Olympian, keeps leaving apple cores scattered around the house.
a Excessive excercise.
b Migraine
c Pituitary tumour
d Pregnancy associated tension headache
e Trigeminal neuralgia
A

pituitary tumour (causing raised ICP)

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4
Q
4.  Aphrodite, a19 year old female sex-worker presents to A&E with a sudden onset headache that is the worst pain she has ever experienced. She occasionally gets mild headaches after sex, and has been given some medication by her GP for his.  She has some neck stiffness and refuses to open her eyes wide or allow them to be examined. 
a Acute glaucoma
b Meningitis 
c Migraine
d Subarachnoid haemorrhage
e Trigeminal neuralgia
A

SAH

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5
Q
5. Leonidas, a 24 year old male, was fencing and suffered and injury to the head when his rival, Xerxes hit him on the head with his shield. Leonidas recovered quickly and was able to continue to fight for the next 20 minutes. However he quickly developed an excruciating headache, started to lose consciousness and had to stop the fight to go to the nearest A&E. He has had a blocked nose for the last week.
Epidural haemorrhage
Intraventricular haemorrhage
Meningitis
Subarachnoid haemorrhage
Subdural haemorrhage
A

Epidural haemorrhage

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6
Q
6. Euclid is a 19 year old male currently studying Maths at university. He has been very unwell for the last few days with fever and headache and admits to becoming a little confused lately. He is very anxious about his upcoming exams. He has been taking caffeine pills to help him with revision, however this has affected his sleep and for the last couple of nights he has developed a stiff neck.
Medication overuse headache
Meningitis 
Migraine
Tension headache
Sinusitis
A

Meningitis

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7
Q
7. Plutarch is a 77 year old male who has come in with a right sided headache. This started yesterday morning and have been getting progressively worse. His memory is a little off because of his dementia, but he says there is a possibility of trauma. His shoulders and neck also feel a little stiff. On examination, there is pain on palpation of the right forehead.
Intracranial space-occupying lesions
Meningitis 
Subarachnoid haemorrhage
Subdural haemorrhage
Temporal arteritis
A

Temporal arteritis

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8
Q
8. Helen is a 40 year old woman with a history of multiple sclerosis. She has developed a headache over the last couple of days. She has travelled the world and rarely had headaches in the past. She has stopped eating, as chewing simply makes her feel worse.
Meningitis
Migraine 
Temporal arteritis
Tension headache
Trigeminal neuralgia
A

Trigeminal neuralgia

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9
Q

what is the mneumonic for sinister causes of headache

A

VIVID

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10
Q

what does VIVID stand for

A
Vascular (SAH/haematoma)
Infection (meningitis/encephalitis)
Vision threatening (temporal arteritis/acute glaucoma)
Intracranial pressure (hydrocephalus)
Dissection (carotid dissection)
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11
Q

what are features of a tension headache

A

acute or gradual onset generalised headache which lasts for a couple of hours
associated with times of stress or lack of sleep

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12
Q

what is the managment for tension headache

A

simple analgesics

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13
Q

what are features of a migraine

A

unilateral pulsating or throbbing headache whichc can last hours to days
associated with an aura (visual or sensory changes)

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14
Q

who does migraine commonly affect

A

women

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15
Q

what is the conservative management for migraine

A

headache diary

to work out and avoid precipitating factors

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16
Q

what is the medical management of migraine

A

sumitriptan
+analgesia (NSAID)
+antiemetic (metoclopramide)

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17
Q

what is the prophylactic management of migraine

A

1st line: propanolol

2nd line: amitriptyline

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18
Q

what could patients with migraine get

A

medication overuse headache with chronic analgesic use

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19
Q

what are features of cluster headache

A
sudden onset (at the same time each day) of unilateral orbital excruciating pain which lasts for minutes
associated with a swollen eye and forehead, nasal congestion
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20
Q

what condition is associated with cluster headache

A

horners

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21
Q

who does cluster headaches commonly affect

A

males

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22
Q

what is the medical treatment for cluster headaches

A

100% O2 through a non-rebreathable mask

sumitriptan (subcut)

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23
Q

what is the prophylactic treatment for cluster headaches

A

verapamil

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24
Q

what are features of raised ICP

A

gradual onset of bilateral headache which is worse when lying down or bending over or coughing
associated with seizures, papilloedema, focal neurology

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25
Q

what are the red flag symptoms in raised ICP

A

seizures
papilloedema
focal neurology

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26
Q

what are causes of raised ICP

A

space occupying lesions
hydrocephalus
trauma

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27
Q

what is the first line investigation for raised ICP

A

urgent CT/MRI to exclude underlying lesion

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28
Q

when are headaches caused by raised ICP worse

A

in the morning

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29
Q

what are features of SAH

A

sudden onset “thunderclap” headache which is commonly at the back of the skull (like being kicked in the back of the head)
associated with syncope, N+V

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30
Q

why does SAH present with signs of meningism

A

meningeal irritation

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31
Q

what causes SAH

A

berry aneurysms at the circle of Willis (associated with Hx or FHx of polycystic kidney disease)

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32
Q

what are risk factors for SAH

A

alcohol
smoking
HTN

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33
Q

what investigations should be performed with suspected SAH

A

1 urgent CT scan (within 12hrs)

2 LP

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34
Q

what risk of mortality is associated with SAH

A

50%

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35
Q

what is the medical management

A

ABC

AB: maintain airway + breathing
C maintain cerebral perfusion
-hydration
-maintain BP

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36
Q

what is the supportive management

A

reduce high ICP
-osmotic diuretic (mannitol)
prevent cerebral artery vasospasm
-nimodipine

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37
Q

what is the definitive surgical treatment for SAH

A

surgical clipping

endovascular coil embolisation

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38
Q

what are features of SDH

A

gradual onset of sleepiness and personality change (diminished verbal and motor response)

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39
Q

what are risk factors for SDH

A

age
accidents (trauma)
anticoagulation

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40
Q

what is the definition of SDH

A

collection of blood between the dural and arachnoid coverings of the brain

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41
Q

is the blood in SDH arterial or venous

A

venous

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42
Q

what is the 1st line investigation for SDH

A

urgent non-contrast CT scan

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43
Q

what is the management for SDH

A

neurosurgery referral

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44
Q

what are features of epidural haemorrhage

A

acute onset headache after a lucid interval

associated with deterioration of GCS and a history of recent direct trauma

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45
Q

what is commonly seen on examination in epidural haemorrhage

A

scalp trauma

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46
Q

definition of epidural haemorrhage

A

collection of blood between the dura and periosteum

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47
Q

is the blood in epidural haemorrage commonly arterial or venous

A

arterial

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48
Q

what is the first line investigation for epidural haemorrhage

A

urgent non-contrast CT scan

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49
Q

why is a non-contrast CT rather than a contrast CT scan ordered in suspected haemorrhages

A

blood is not contained by vessels so contrast can leak into surrounding vessels

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50
Q

what is the most common cause of extradural

A

high impact trauma

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51
Q

what artery is most commonly affected in extradural

A

middle meningeal artery

52
Q

what is the most common cause of SAH

A

ruptured aneurysms

53
Q

what is the most common cause of SDH

A

rupture of vein by minor head trauma

54
Q

what is the onset of extradural

A

sudden onset

55
Q

what is the onset of SAH

A

sudden onstt

56
Q

what is the onset of SDH

A

gradual onset

57
Q

what symptoms are associated with extradural

A

blackout followed by a lucid interval followed by a rapidly declining GCS

58
Q

what are symptoms associated with SAH

A

worse headache ever

thunderclap

59
Q

what are symptoms associated with SDH

A

no/mild symptoms

  • worsening confusion
  • fluctating consciousness
60
Q

what are features of meningitis

A

sudden onset headache
associated with meningism (headache, stiff neck, photophobia)
confusion and seizures are associated

61
Q

what investigations are completed for meningitis

A

LP
-CSF protein/glucose
blood culture
CT head

62
Q

what is giant cell arteritis

A

vasculitis affecting arteries in the head

63
Q

what could giant cell arteritis of the opthalmic artery cause

A

blindness

64
Q

what are features of temporal giant cell arteritis

A

onset of headache over a couple of days which is usually unilateral and localised to the scalp
associated with pain when eating or brushing hair and a visual disturbance

65
Q

what would be found on examination of giant cell arteritis

A

scalp tenderness

66
Q

what condition is giant cell arteritis associated with

A

polymyalgia rheumatic (pain and stffness of the shoulders and upper arms)

67
Q

what is the management for giant cell arteritis

A

urgent prednisolone (delay can cause blindness)

68
Q

what are features of trigeminal neuralgia

A

shooting facial pain in the distibution of the Vth nerve, commonly unilateral
this is provoked by washing, shaving or chewing

69
Q

what are risk factors for trigeminal neuralgia

A

elderly
MS
(female + HTN)

70
Q

what is the management for trigeminal neuralgia

A

anticonvulsants (cabamazepine)

71
Q

what is a classic history of sinusitis

A

7-10 day history of fever and headache with nasal congestion or discharge

72
Q

how does acute glaucoma present

A

headache, painful eye, visual changes, vomiting

73
Q

what is the management for acute glaucoma

A

acetazolamide (carbonic anhydrase inhibitor)

timolol (BB)

74
Q
  1. 70 year old Herodotus is brought in by his daughter to the GP. Over the last week he has developed a headache which lasts most of the day and rarely goes. He lives with his daughter and son-in-law as he is prone to falls due to his recent left hip replacement. The daughter also mentions that his father’s behavior has changed lately and tends to exaggerate some of his stories.
    What do you think is the most important step in your management plan?
    MRI scan
    Routine CT scan
    Sumitriptan + NSAIDs
    Urgent CT scan
    Watchful waiting
A

Urgent CT scan

75
Q
10.  Alexander, known to his mates as Alex the G, is a 32 year old soldier who has just returned from a tour in Iran. He tells you that he has been getting throbbing bilateral head pain, and puts this down to lack of sleep.  As a general, he has multiple reports to write and is finding this difficult with his four friends constantly bickering about one thing or the other. He hasn’t tried any medication and asks that you prescribe some sleeping pills. What is the most appropriate management?
Diazepam
Codeine
NSAIDs
Topiramate
Refer to A&E
A

NSAIDs

76
Q
11. Pythagoras is a 40 year old man who suffers from headaches. 3 weeks ago he was prescribed ibuprofen and has taken it religiously. Initially these worked really well, however now the headaches have returned and are worse than ever. He is very angry and does not think you are taking the right angle towards managing his issue. What is the next course of management?
Antibiotics
Add a β-blocker
Refer to A&E
Switch medication to carbamazepine
Ask to stop ibuprofen and see in 2 weeks
A

Ask to stop ibuprofen and see in 2 weeks

77
Q
  1. Hippocrates is a 71 year old homeopath who presents with a left sided headache which came on yesterday morning. He tried to tread it with a clever paste made of garlic, vinegar and honey. When he applied the paste he was in great pain, and so believed that his remedy was working. However, his skeptical son told him to see “another doctor” for treatment. What is the most important next step?
    Prescribe prednisolone and refer patient to A&E
    Prescribe sumitriptan and NSAIDs
    Refer to A&E for urgent CT scan
    Refer to A&E for urgent non-contrast CT scan
    Refer to A&E for MRI
A

Prescribe prednisolone and refer patient to A&E

78
Q

A 25-year-old man was hit on the side of the head with the ball, whilst playing cricket. He recovered enough to finish off the game. He then presented to A&E 8 hours later with a severe headache and vomiting. On Examination he pupil are looking down and out, and soon after this he rapidly loses consciousness

Subarachnoid Haemorrhage
Extradural Haemorrhage
Stokes-Adam’s Attack
Postural Hypotension
Hypoglycaemia
A

extradural

79
Q

A 52 year old fund manager with a history of previous heart attacks, feels some palpitations and collapses. A witness said that he went very pale as he collapsed but then became flushed and regained consciousness after 30 seconds.

Subarachnoid Haemorrhage
Extradural Haemorrhage
Stokes-Adam’s Attack
Postural Hypotension
Hypoglycaemia
A

Stokes-Adam’s Attack

80
Q

A previously well 14 year old girl collapses after being in a crowd for 2 hours at a pop concert.

Cardiac Arrhythmia
Aortic Stenosis
Vasovagal Syncope
Postural Hypotension
Situational Syncope
A

Vasovagal Syncope

81
Q

A 75-year-old man is found on his bedroom floor by his wife and is now conscious. He got out of bed in the middle of the night to go to the toilet and felt dizzy and fell to the ground. He is on treatment for hypertension and has no other medical problems.

Cardiac Arrhythmia
Aortic Stenosis
Vasovagal Syncope
Postural Hypotension
Situational Syncope
A

Postural Hypotension

82
Q

A 56 year old lady collapses whilst running for the bus. O/E there is a thrusting apex beat and an ejection systolic murmur. This is best heard on expiration and radiates to the carotids.

Cardiac Arrhythmia
Aortic Stenosis
Vasovagal Syncope
Postural Hypotension
Situational Syncope
A

Aortic Stenosis

83
Q

A 20 year old man, who was picked up by the police, is behaving irrationally & is confused & irritable. He is pale & sweaty & smells of alcohol. He keeps asking for biscuits.

Subarachnoid Haemorrhage
Extradural Haemorrhage
Stokes-Adam’s Attack
Postural Hypotension
Hypoglycaemia
A

Hypoglycaemia

84
Q

44 y/o gentleman. On examination he appears drowsy, only opening his eyes in response to speech, he seems confused and disorientated, and when assessing his movements he is able to obey commands. Calculate his GCS

6
8
9
10
13
A

13

85
Q

A 65 year old man with a history of an MI 2 years ago. He lost consciousness and presents to you 36 hours later with reduced power in his left arm and leg.

Stroke
Subdural Haematoma
Encephalitis
SOL
Epilepsy
A

Stroke

86
Q

A 21-year-old man is walking down the street to visit his friends while suddenly he falls to the ground unconscious. His body goes stiff and then he begins to jerk his arms. He becomes incontinent of urine.

Stroke
Subdural Haematoma
Encephalitis
SOL
Epilepsy
A

Epilepsy

87
Q

what is a mneumonic for blackouts?

A

COLLAPSED

Carotid sinus syncope
Orthostatic (postural) hypotension
refLex - vasovagal syncope
Low glucose
Arrythmias/stoke-adams attack
Panic - anxiety - hyperventilation
Situational syncope
Epilepsy
Drop attacks
88
Q

what is a classic feature of a extradural haemorrhage

A

lucid interval following LOC

89
Q

what is the blood in an extradural haemorrhage

A

arterial

90
Q

what are classic features of a SDH history

A

Hx of falls and progressive confusion

91
Q

what is the blood in SDH

A

venous

92
Q

what are causes of raised ICP

A

SHIT

abSceSS
Haemorrhage
Infarction
Tumours

plus cerebeal oedema and trauma

93
Q

what are signs of raised ICP

A
headache
N+V
altererd GCS
papilloedema
pupil changes
94
Q

what pupil changes can occur in raised ICP

A

dilated

down and out

95
Q

what are signs of herniation in raised ICP

A

opthalmoplegia
ataxia
apnoea

96
Q

what is the definition of postural hypotension

A

drop in systolic BP >20mmHg or diastolic BP >10mmHg after standing for 3minutes vs lying

97
Q

what test is used to confirm postural hypotension

A

tilt test

98
Q

who is postural hypotension common in

A

elderly

99
Q

what conditions related to peripheral neuropathy cause postural hypotension

A

inadequate vasomotor reflex
DM
parkinsons
MSA

100
Q

how low do glucose levels have to be before symptoms of hypoglycaemia show

A

<3mmol/L

101
Q

what is the treatment for hypoglycaemia

A

IV dextrose or IM glucagon

102
Q

what does a GCS below 8 suggest

A

coma or severe injury

103
Q

A 65-year-old hypertensive man has complained of losing vision twice in one eye, which lasted for a few hours and then went back to normal. He says it’s like ‘a black sheet falling over the front of my eye’.

Right-sided Stroke
Transient Ischaemic Attack
Meningitis
Encephalitis
Left-side Stroke
A

Transient Ischaemic Attack

104
Q

An 80-year-old woman who is a smoker was brought into A&E from a residential home where her carers noticed that she had difficulty swallowing and that she also had difficulty moving her left arm and leg for the past few days.

Right-sided Stroke
Transient Ischaemic Attack
Meningitis
Encephalitis
Left-side Stroke
A

Right-sided Stroke

105
Q

A 30-year-old woman experienced a strange feeling in her stomach, followed by stiffness & jerking in the left arm. Afterwards, she felt drowsy but remembers everything.

Myoclonic Seizure
Complex Partial Seizure
Simple Partial Seizure
Tonic-Clonic Seizure
Absence Seizure
A

Complex Partial Seizure

106
Q

A 21-year-old man is walking down the street to visit his friends while suddenly he falls to the ground unconscious. His body goes stiff and then he begins to jerk his arms. He becomes incontinent of urine.

Myoclonic Seizure
Complex Partial Seziure
Simple Partial Seizure
Tonic-Clonic Seizure
Absence Seizure
A

Tonic-Clonic Seizure

107
Q

what are signs of a stroke

A
UMN lesion
contralateral motor and sensory signs
no fasciculations
no muscle wasting
weakness (esp of arm extensors and leg flexors)
hyperreflexia
positive babinski sign
pronator drift
108
Q

what are features of a posterior cerebral artery lesion

A

homonymous hemianopia
visual agnosia
prosopagnosia

109
Q

what is amaurosis fugax`

A

transient and painless loss of vision in one eye due to embolus into the central retinal artery

110
Q

what features indicate a simple partial seizures

A

no LOC

no post-ictal phase

111
Q

what features indicate a complex parpostial seizure

A

most commonly arise from temporal love (deja-vu, depersonalisation, altered emotion)
consciousness impaired
post-ictal confusion

112
Q

what does tonic mean

A

limb stiffening

113
Q

what does clonic mean

A

limb jerking

114
Q

what is status epilepticus

A

continuous seizure lasting >30mins

115
Q

what is the medical management for status epilepticus

A

slow IV bolus lorazepam a second dose is administered if no response in 10 minutes
if still no response IV phenytoin or diazepam

116
Q

what is Brudzinski sign

A

indication for meningitis

passive flexion of the neck causes flexion of the legs

117
Q

what is encephalitis

A

inflammation of brain parenchyma

118
Q

what are metabolic causes of LOC/seizure

A

hyponatraemia

hypocalcaemia

119
Q

what classic history of hyponatraemia

A

headaches, vomiting, drowsiness + seizures

associated with thiazide diuretics

120
Q

what is a classic history of hypocalcaemia

A
complication of thyroid surgery
CATS
convulsions
arrythmias
tetany
spasms
121
Q

what signs are associated with hypocalcaemia

A

chovesteks sign

trousseus sign

122
Q

A 50-year-old man presents with an instantaneous onset of a severe headache, followed by drowsiness & vomiting. Shortly after presentation he loses consciousness

Subarachnoid Haemorrhage
Extradural Haemorrhage
Anaemia
Postural Hypotension
Hypoglycaemia
A

SAH

123
Q

An 80 year old man fainted with a 2 week history of abdominal pain and coughing up a black coffee-ground like substance. He has been feeling irritable, tired and sleepy.

Subarachnoid Haemorrhage
Extradural Haemorrhage
Anaemia
Postural Hypotension
Hypoglycaemia
A

Anaemia

124
Q

A 10-year-old girl is not doing well at school, her teacher says she doesn’t concentrate and shows no interest. Her parents also noticed the girl has moments (around 10secs) when she just stares blankly, blinking and then returns to normal. It happens up to several times an hour.

Myoclonic Seizure
Complex Partial Seziure
Simple Partial Seizure
Tonic-Clonic Seizure
Absence Seizure
A

Absence Seizure

125
Q

A 71 year old man with long standing hypertension lives on his own. He is found by his son with marked right upper limb weakness and difficulties with speech. He is now incontinent of urine and has some personality changes.

Right-sided Stroke
Transient Ischaemic Attack
Meningitis
Encephalitis
Left-side Stroke
A

Left-side Stroke (with frontal lobe involvement for personality changes)

126
Q

A 87-year-old lady had a seizure at home. Her husband says she has been drowsy for the last couple of days. She is otherwise in good health but she has recently started antihpertensive drugs. On examination, her skin turgor is reduced.

Hypercalcaemia
Hypocalcaemia
Hyperglycaemia
Hypoglycaemia
Hyponatraemia
A

Hyponatraemia

127
Q

A 66-year-old was getting increasing confused over the last couple of days. She was admitted after a seizure. She appears distressed and is pyrexial with mild meningism but no rash. A CT head scan shows changes in the left temporal lobe and cerebral oedema.

Right-sided Stroke
Transient Ischaemic Attack
Meningitis
Encephalitis
Left-side Stroke
A

Encephalitis