Med Review sheet

Question 1

Conjugated Equine Estrogens

Answer 1

Trade name: Premarin
Category: Hormone replacement therapy-estrogen
Use: Menopausal sx
Dose: 0.3mg PO qday
AE: N, HA, bloating, bleeding, breast tenderness
CI: hx or active thromboemolic disease, breast CA or other estrogen dependent neoplasm, pregnancy, liver disease, undiagnosed vaginal bleeding, prevention of cardio disease or dementia

Question 2

Medroxyprogesterone

Answer 2

Trade name: Provera
Category: Hormone Replacement therapy-progestogen
Use: Menopause sx
Dose: 2.5mg qday for 12-14 days
AE: N, HA, wt gain, bleeding,irritability, depression
CI: hx or active thromboemolic disease, breast CA or other estrogen dependent neoplasm, pregnancy, liver disease, undiagnosed vaginal bleeding, prevention of cardio disease or dementia

Question 3

Estradiol transdermal

Answer 3

Trade name: Alora, Climara, Estraderm, Vivelle
Category: Hormone replacement therapy- estrogen patch
Use: Menopause sx
Dose: 0.025mg q24h; change patch 2x/week
AE: N, HA, bloating, bleeding, breast tenderness
CI: hx or active thromboemolic disease, breast CA or other estrogen dependent neoplasm, pregnancy, liver disease, undiagnosed vaginal bleeding, prevention of cardio disease or dementia

Question 4

Estradiol/Norethindrone Acetate

Answer 4

Trade name: Activella (oral) and Combipatch (transdermal)
Category: Hormone replacement therapy-combination
Use: Menopause sx
Dose: Oral 0.5/0.1 mg PO qday; Transdermal 0.05/0.14mg q24h. Apply 1 patch 2x/week
AE: N, HA, bloating, bleeding, breast tenderness
CI: hx or active thromboemolic disease, breast CA or other estrogen dependent neoplasm, pregnancy, liver disease, undiagnosed vaginal bleeding, prevention of cardio disease or dementia

Question 5

Norgestimate and Ethinyl estradiol

Answer 5

Trade name: Sprintec
Category: Oral contraceptive
Use: Oral contraceptive
Dose: 0.25mg/35mcg Take 1 pill PO qday for 21 days
AE: could depend on hormonal imbalance from pill iteself (ex. breakthrough bleeding is too little estrogen or progestin) or Abd pain, Chest pain, HA, Eye Problems, Severe leg pain
CI: CI: hx or active thromboemolic disease, breast CA or other estrogen dependent neoplasm, pregnancy, liver disease, undiagnosed vaginal bleeding, hx of stroke or CAD, heavy smoker, migraine, postpartum

Question 6

Raloxifene

Answer 6

Trade name: Evista
Category: MEAA/SERM
Use: Osteoporosis
Dose: N/A
AE:worse hot flashes, VTE, leg cramps
CI

Question 7

Alendronate

Answer 7

Trade name: Fosamax
Category: Bisphosphonae
Use: Osteoporosis
Dose: 35mg/wk prevention and 70mg/wk tx
AE: GI upset, esophageal ulcer, jaw osteonecrosis, femur fx
CI

Question 8

Calcium carbonate

Answer 8

Trade name: Tums, Os-Cal, Caltrate
Category: Calcium supplement
Use: Osteoporosis
Dose: 500-600mg bid or tid
AE: constipation, GI irritation, flatulence, rare kidney stones, hypercalcemia
CI

Question 9

Calcitonin

Answer 9

Trade name: Miacalcin
Category: Anti-resorptive Therapy
Use: Osteoporosis
Dose: N/A
AE: rhinitis, epistaxis
CI