Mechanics of Breathing I Flashcards
muscles of inspiration
diaphragm
external intercostals
accessory muscles of inspiration?
scalenus
sternomastoids
pectoralis
expiration muscles?
passive during rest
forced:
internal intercostals
abdominal muscles
external intercostals?
inspiration
internal intercostals?
expiration
chest wall?
wants to spring outward
lung?
wants to collapse inward
chest wall and lung create?
negative intrapleural pressure
pneumothorax?
intrapleural and atmospheric pressure are equal
pressure-volume curve of isolated lung
volume never zero
-can’t get all out of lung
compliance
compliance = deltaV / deltaP
slope of pressure-volume curve
compliance determined by?
elastic recoil
surface tension
emphysema
increased slope, more compliant
fibrosis
decreased slope, less compliant
what determines elastic recoil?
elastic tissue
-elastin and collagen
surface tension?
reduced by surfactants
functions of surfactant?
lower surface tension
increase alveolar stability
keep alveoli dry
surfactant graph?
mimics the shape of prssure-volume curve
without surfactant production?
complete 38 weeks (before 32 weeks bad)
- surface tension is increased, therefore the compliance is reduced
- alveoli would collapse
- alveoli would not be dry
high surface tension and low compliance
at low pressure and volume
- as volume and pressure increase
- increase in elastic recoil of lung
ventilation at apex
intrapleural pressure more negative at apex
greater transmural pressure gradient
alveoli larger, less compliant
less ventilation at apex
perfusion at apex
lower intravascular pressures
less recruitment, distention
higher resistance
less blood flow
support of base of lung?
higher pressure required
resting chest wall
at airway pressure = 0
resting respiratory level
at functional residual capacity (FRC)
-lung and chest movements balanced
at volumes above minimal volume for lung?
lung wants to retract
volumes above FRC?
net force inward
volumes below FRC?
net force outward
volumes at FRC?
zero net force
kyphoscoliosis?
moves the pressure-volume down
-bc of change in chest wall compliance decrease
obese patients
decreased expiratory reserve volume alot
weight on chest restricting movement
-therefore global decrease in all lung volumes with significant decrease in ERV
shift in curve to right