MCBG Flashcards

1
Q

Where is rRNA found

A

In nucleolus

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2
Q

Peroxisomes are for

A

Chemical detoxification

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3
Q

RER role

A

Synthesis of proteins

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4
Q

How many deoxyribose in DNA

A

2

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5
Q

DNA polymerase works

A

3 - 5

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6
Q

COOH is a proton

A

Donor

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7
Q

Amino group is a

A

Proton acceptor

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8
Q

increased CO2 causes

A

Increased CO2 causes PH to decrease, Bohr effect shifts curve right

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9
Q

What is the donor molecule when an enzyme is phosphorylated

A

AMP

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10
Q

Primary antibody in western blot binds to

A

A specific target protein

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11
Q

Post translational modification of collagen

A
  • O linked glycosylation takes place in Golgi
  • Removal of amino acids from N and C terminus of procollagen in extracellular space outside fibroblast
  • N linked glycosylation- glycosyl binds to asparagine
  • O linked glycosylation- glycosyl binds to threonine and serine
  • Serine, threonine and tyrosine can be phosphorylated
  • N linked glycosylation in ER
  • C chain cleaved off of insulin
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12
Q

Nuclear envelope dissolves in

A

Prometaphase

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13
Q

Transcription happens in

A

Nucleus

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14
Q

Translation happens in

A

Cytosol

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15
Q

chronic myeloid mutation in leukaemia caused by

A

Robertsonian mutation, non sense mutation = premature STOP codon

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16
Q

DNA PKs only in

A

Non homologous end joining

17
Q

Ligation occurs only in

A

Non homologous end joining

18
Q

DNA mismatch repair is defective in

A

HNPCC