MCAT Misc. Flashcards
What are the universal emotions?
Fear, anger, disgust, happiness, surprise, and sadness
What are the 3 components of emotion?
(1) Cognitive (2) Physiological (3) Behavioral
psychoeducation
the education offered to individuals with a mental health condition and their families to help empower them and deal with their condition in an optimal way.
3 Types of organizations:
”
(1) Coercive: members forced to join
(2) Normative: members volunteer to participate
(3) Utilitarian: members are compensated for their involvement”
2 key features of viruses
(1) Self-replicating (2) Must reproduce within specific host cell (“obligate parasites”)
Generalized phage and animal virus life cycles
(1) Attachment (2) Penetration (3) Entry of viral genetic code (4) Use host mechanism to replicate (5) Self-assemblage and release of new viral particles
Attachment: phages vs. animal viruses
Phages: tail fibers attach to cell wall proteins; animal viruses: attach to plasma membrane proteins and glycoproteins
Penetration: phage vs. animal viruses
Phages: viral DNA injected into host cell; Animal Viruses: capsid enters by endocytosis or fusion
Biosynthesis: phage vs. animal viruses
phages: in cytoplasm; animal viruses: in nucleus (DNA viruses) or in cytoplasm (RNA viruses)
Prion
(A subviral particle); an infectious agent composed entirely of protein material (PrP = prion protein) that can fold in multiple structurally distinct ways - at least one which is transmissible to other prion proteins, leading to disease that is similar to viral infection
Viroid
(A subivral particle - the smallest infectious pathogens known); composed of a circular, short-stranded, RNA without a protein coat; Inhabit higher plants - in which most cause disease
Michaaelis-Menton Equn:
V = Vmax*[S] / [S] + Km —-> when Km = [S], then V = 1/2 * Vmax
competitive inhibition
Inhibitor binds to active site of enzyme; Increases Km; same Vmax
Non-competitive inhibition vs. Mixed inhibtion
“Mixed inhibitor binds to allosteric site on enzyme, causing enzyme deactivation; can bind to free enzyme OR enzyme-substrate complex; Usually effects both Km and Vmax;
-Non-competitive inhibitor = type of mixed inhibitor that binds to E or ES complex equally, thus decreases Vmax, but leaves Km unchanged”
zymogen
unactive form of an enzyme —> requires a covalent modification to become active
Uncompetitive inhibition
Only binds to the ES complex; Km and Vmax are both decreased by proportional amounts (so Lineweaver Burke Plot slope doesn’t change)
cofactors and coenzymes
Cofactors = non-protein helper molecules that bind to enzymes to help them work optimally; coenzymes = organic (carbon-based) cofactors
Most common sources of coenzymes
Dietary vitamins (particularly water-soluble vitamins); ex: Vitamin C is important voenzyme for some enzymes in building collagen
Enzyme Classes
(1) Oxidoreductase (2) Transferase (3) Hydrolase (addition of water) (4) Lyase (remove groups w/o hydrolysis) (5) Isomerase (6) Ligase (join 2 molecules, using energy)