Maternal medicine Flashcards
What is the definition of maternal death?
Death WHILST PREGNANT
OR
WITHIN 42 DAYS OF END OF PREGNANCY
Cause: related to or aggravated by pregnancy or management
*includes birth, ectopic pregnancy, miscarriage or termination of pregnancy
What is the definition of ‘direct’ maternal death?
death resulting from obstetric complications, interventions, omissions or incorrect treatment
What is the definition of ‘indirect’ maternal death?
deaths resulting from previous EXISTING DISEASE or DISEASE DEVELOPED DURING PREGNANCY
not the results of obstetric cause but AGGRAVATED BY BEING PREGNANT
What is a late maternal death?
Deaths occurring between 42 DAYS and 1 YEAR after the end of pregnancy*
direct or indirect maternal causes
*inclused ectopic pregnancy, miscarriage or termination
What is ‘coincidental’ maternal death?
Death from UNRELATED causes which happen to occur in pregnancy or puerperium
What cardiac problems would we be concerned about in a pregnant woman?
congenital or acquired CHD
What are some symptoms women may experience whilst pregnant, that could indicate cardiac problems?
Fatigue Fainting Chest pain Shortness of breath Difficulty breathing while sleeping Palpitations
Have a low threshold to investigate
What would you keep in mind for the monitoring and management of a pregnant woman with cardiac health problems?
MDT - obstetrician led care
Consider early delivery (time of delivery is more important than mode of delivery)
What would you keep in mind for the monitoring and management of a pregnant woman with epilepsy?
MDT - obstetrician led care?
Patient may/may not require medication
Folic acid 5 mg/day
Postnatal liaison with patient carer
What are the risks associated with being on anti-epileptics during pregnancy?
Fetal abnormalities (NTD,cardiac, facial )
Frequent seizures
Status epilepticus
What does essential hypertension during pregnancy increase the risk of?
Maternal pre-eclampsia/eclampsia and placental abruption
Maternal morbidity and mortality, especially with very high systolic blood pressure
Intrauterine fetal growth restriction and preterm delivery
Neonatal morbidity and mortality
What drugs should ideally be given for HTN in pregnancy (instead of ACEi)?
labetalol
nifedipine
methyldopa
(consider aspirin)
What is worth noting about ACEi (ie. why do they need changing to labetalol, nifedipine and methyldopa)?
teratogenic
How would you manage a pregnant woman with essential hypertension?
frequent monitoring of both mother and foetus
change teratogenic drugs to labetalol, nifedipine and methyldopa
consider low-dose aspirin from 12 weeks
How does maternal drug abuse effect the mother, pregnancy process and the foetus?
Maternal death from overdose
Blood-borne diseases (HBV,HCV,HIV)
Fetal growth restriction and stillbirth
Abruption placenta
Preterm delivery
Difficulty to establish venous access
Neonatal withdrawal syndrome
- Patients at higher risk of violence
How would you manage a pregnant mother with drug abuse problems?
Obstetrician-led care
More frequent monitoring eg. growth scan
encourage mothers to participate in methadone programme
think re. safeguarding issues
How does maternal diabetes mellitus effect the mother, pregnancy process and the foetus?
Maternal:
Hypo-/hyperglycemia
Ketoacidosis
Hypertension, pre-eclampsia and eclampsia
Fetal: Sudden IUD Congenital abnormalities Shoulder dystocia Neonatal hypoglycaemia
How would you manage a mother with diabetes mellitus?
screening of high risk groups
Might give low-dose aspirin to prevent pre-eclampsia
Need to use 5mg folic acid (pre-conceptually if possible)
MDT care - obstetrician led care
Increased monitoring e.g.. growth scans etc.
planned delivery at term, 39/40
Are pregnant women more or less likely to suffer with VTE?
more likely - some higher risk groups
What makes woman more likely to be at risk of VTE during pregnancy?
Obesity
FHx
Smoking
How would you manage a suspected VTE in pregnancy?
Diagnosis:
Treatment:
Post-natal advice:
What can cause maternal psychiatric disorders?
pre-existing mental health disorders +/- personal and social demands of pregnancy and caring for new baby
- may recur/worsen in postnatal period
What postpartum psychiatric disorder is associated with bipolar effective disorder?
early postpartum psychosis
Which women need urgent referral to a specialist perinatal mental health team?
New thoughts of violent self harm
sudden onset or rapidly worsening mental symptoms
persistent feelings of estrangement for their baby
What is normal dose of folic acid given to pregnant women? How is this different in epileptic mothers?
400 mcg normal
5mg in epilepsy (try to reduce neural tube defects)
What might you need to do to anti-epileptic drugs in a pregnant women? Who would do this?
may need to increase or decrease
neurologist
What vitamin is given to a mother with epilepsy? When is it given?
Vit K
In the last 4 weeks
Is breastfeeding encouraged or discouraged if the mother is on anti-epileptics?
encouraged
What elements of labour ay increase risk of seizures (by lowering threshold)
Stress
sleep deprivation
medication
How might epilepsy impact contraceptive choice?
May need a higher dose of oestrogen in pill (if on anti-epileptics that induce hepatic enzymes)
When might you not use methyldopa in pregnancy for HTN?
risk of depression
When might you not use labetalol in pregnancy for HTN?
asthmatic woman
Why would you give low dose aspirin (from 12 weeks) in pregnant women with long-term HTN?
Reduce risk of: pre-eclampsia
growth restriction
Which elicit drug is most likely to cause abruption of placenta?
cocaine (due to HTN)
How can heroin effect pregnancy?
Can lead to miscarriage
What is macrosomia?
A baby >4.5/5Kg
What are some risk facts for shoulder dystocia?
Diabetes Mellitus (mascrosomic baby)
macrosomic baby
What are babies with diabetic mothers at risk of? hypoglycaemia or hyperglycaemia?
hypoglycaemia
Which women might need to be screened for gestational diabetes?
BMI >30
Ethnicity (afro-carribean, asian)
FHx
What effects the mode of delivery in diabetic patient?
Depends on size of baby
Risk of stillborn
What syndrome increases risk of VTE?
May-Thurber syndrome (narrowed L iliac vein by pressure from R iliac vein)