Early pregnancy disorders Flashcards

1
Q

What is the definition of early pregnancy?

A

First half of pregnancy:

Up to about 20 weeks

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2
Q

What are some common problems in early pregnancy?

A

Miscarriage
Ectopic pregnancy
Hyperemesis

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3
Q

What are some common symptoms of miscarriage?

A

Bleeding
Pain

May not know - may have to be told secondary to ultrasound scan

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4
Q

How do you tell the difference between miscarriage or ectopic pregnancy?

A

ultrasound scan

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5
Q

What service exists for women to go if they have pain and bleeding?

A

Early pregnancy unit

GATU - if referred to by doctor

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6
Q

What is the first thing you would do if a ‘pregnant’ woman presents with pain and bleeding

A

pregnancy test - if -ve, definite miscarriage (or were never pregnant)

Pregnancy test +ve - need to do US scan

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7
Q

Why does a transvaginal USS need to be done to a woman with ?miscarriage?

A

Better image

won’t disturb or put the pregnancy at risk

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8
Q

What are the two things you want to know from a USS in ?miscarriage, ?ectopic pregnancy?

A

Location

Viability

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9
Q

What sorts of things might you be able to see in a transvaginal USS?

A

intrauterine sac, 5 weeks after LMP 10-15 mm
5+ weeks: sac + yolk sac
6 weeks: foetal pole/baby (baby is 5mm at this stage)
6+ weeks: Foetal heart sounds (needs to be 7mm size)

(move all of these forward by one week if you scan abdominally - 6 weeks = intrauterine sac, 6+ weeks = yolk sac etc.)

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10
Q

If you see a foetus that is AT LEAST 7mm without any heart sounds, what does this indicate?

A

pregnancy not continuing

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11
Q

If a baby is less than 7mm in size, what do you have to tell the mother re. diagnosing miscarriage/ectopic etc.?

A

they have to wait

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12
Q

What is the cut off for being confident about viability of foetus? why?

A

7mm

needs to be this size to see heart

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13
Q

What might be the case if there’s a positive pregnancy test but an empty uterus on transvaginal USS?

A

ectopic pregnancy
complete miscarriage (foetus has already gone)
too small to be seen

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14
Q
How do you differentiate between whether a woman has an: ectopic pregnancy
complete miscarriage (foetus has already gone)
too small to be seen?
A

there might be free fluid in the push of douglas or in pelvis

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15
Q
How do you differentiate between whether a woman has an: ectopic pregnancy
complete miscarriage (foetus has already gone)
too small to be seen?
A

USS: there might be free fluid in the push of douglas or in pelvis (due to rupture)

beta hCG (levels in blood): in early pregnancy, quantity will increase rapidly
in miscarriage, quantity will decrease rapidly
in ectopic, ‘sub-optimal rise’ - rise of less than 50%

Laparoscopy - only definitive diagnosis of ectopic

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16
Q

What proportion of ectopic pregnancies resolve spontaneously?

17
Q

How can you manage a non-viable early stage pregnancy?

A

conservative (can take months to sort itself out, depending on circumstances)

Medical: prostaglandin eg. misoprostol (encourages uterine activity). CAN’T GIVE IN SEVERE ASTHMA
miscarriage usually complete between 48hrs-7days

Surgical: surgical management of miscarriage (inpatient, under GA) aka. evacuation of retained products of conception
OR
MVA - manual vacuum aspiration (Outpatient, under local)

18
Q

What is the most common form of termination with a pregnancy of less than 7 weeks?

19
Q

What is the benefit of MVA over surgical management of miscarriage?

A

quicker and less complications

20
Q

When would you only offer conservative or medical management of miscarriage?

A

when baby gets over a 12 week size

21
Q

How long should women wait (treat conservatively) before being offered medical or surgical management of miscarriage? (technically, locally this isn’t done)

22
Q

How long do women need to wait before trying for a baby again?

A

After next period

23
Q

How would you manage an ectopic pregnancy?

A

Medical: methotrexate - singular IM injection

24
Q

How would you manage an ectopic pregnancy?

A

Medical: methotrexate - singular IM injection

Surgical: laparoscopic salpingectomy (most common treatment)

25
Why is laparoscopy the most common treatment for ectopic pregnancy?
only definitive diagnosis of ectopic pregnancy can only give methotrexate if you're CERTAIN it's an ectopic pregnancy, therefore there is a risk of giving this when the pregnancy isn't ectopic therefore, better in terms of risk, as needs to be done for diagnosis anyway
26
What is one of the benefits of methotrexate?
Tube not as damaged (doesn't necessarily have to be removed) Only as damaged as it was prior to methotrexate
27
When might you especially consider methotrexate for ectopic pregnancy?
if woman has already had tube removed
28
Where can you recommend women (and men) go post-miscarriage?
miscarriage association