Foetal development Flashcards
On what day of the menstrual cycle does ovulation occur?
day 14
Where does fertilisation and conception take place?
fallopian tube
What are the stages of cell division?
Zygote
Morula
Blastocyst
After conception, where does the blastocyst travel to?
uterine cavity
On what day does implantation in to uterine cavity take place?
day 23
What happens after implantation of blastocyst into decidua?
hCG released
stimulates ovary to produce progesterone
For how long do HCG levels rise?
rise rapidly up to 10 weeks
What is the basis of a pregnancy test?
HCG levels
How is HCG detected in pregnancy tests?
detected in serum and urine 4 weeks after LMP
What concentration of HCG is detected in a urine +ve PT?
Urine PT +ve when HCG concentration reaches 25 IU/ml
When does early implantation generally take place?
12 days post conception
Which hormone is the main pregnancy hormone?
Progesterone
Which key areas of maternal physiology are effected by progesterone?
cardiovascular
respiratory
uterine quiescence
immune system
How do you diagnose pregnancy?
Clinical: symptoms
signs
Investigations: hCG
USS
What are the two main routes of USS?
transvaginal or transabdominal
What are key dates in foetal development?
4-5 weeks: gestation sac 6mm
5-6 weeks: yolk sac
6 weeks: foetal pole 5mm
6-7 weeks: foetal heart activity
8 weeks: limb buds, foetal movements
How does the size of a foetus change in between weeks 6-12 weeks?
doubles in size every week
What occurs in the uterus/to the foetus in the first 12 weeks of pregnancy?
organs develop
placenta assumes major role (gas exchange, nutrient waste transfer, steroidogenesis)
In which timeframe is their the highest risk of miscarriage during pregnancy?
within the first 12 weeks
What role does the placenta play in the first 12 weeks of pregnancy?
gas exchange
nutrient/waste transfer
steroidogenesis
What are two important complications of early pregnancy?
miscarriage
ectopic (tubal) pregnancy
How many days is the menstrual cycle?
28 days (from first day of LMP to first day of next MP)
Which hormone peaks to trigger ovulation around day 14?
luetnising hormone