Maternal Adaptation During Pregnancy Flashcards

1
Q

Fundus

A

top of the uterus

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2
Q

Leukorrhea

A

the white vaginal discharge with pregnancy

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3
Q

Tubercles of Montgomery

A

sebaceous glands responsible for nipple lubrication during breast feeding

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4
Q

Peristalsis

A

involuntary constriction and relaxation of the muscles of the intestines; creates a “wave-like” motion that pushes contents of bowel forward

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5
Q

Hypercholesterolemia

A

high levels of cholesterol in the blood

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6
Q

Cardiac Output

A

product of heart rate or the number of heartbeats per minute, and the stroke volume

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7
Q

Stroke volume

A

the volume of blood pumped from the ventricle per heartbeat

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8
Q

What is a normal adult cardiac output?

A

4.7 L blood per minute

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9
Q

Tidal Volume

A

the volume of air inhaled

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10
Q

Morphology

A

the study of structure or how something is made

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11
Q

Central Pallor

A

a normal red blood cell has an area of pallor in its center

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12
Q

Trimester

A

three 13 week intervals of pregnancy

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13
Q

Signs and Symptoms of Pregnancy

A
fatigue 
breast tenderness
nausea and vomiting 
amenorrhea 
urinary frequency
hyperpigmentation of the skin
fetal movement 
uterine enlargement 
breast enlargement
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14
Q

Hyperpigmentation of the skin occurs when?

A

16 weeks

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15
Q

Fetal movement (quickening)

A

16-20 weeks

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16
Q

Uterine enlargement

A

7-12 weeks

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17
Q

Breast enlargement

A

6 weeks

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18
Q

Braxton Hicks contractions

A
16-28 weeks 
function is to efface or thin the cervix in the last month of pregnancy
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19
Q

When will you see a positive pregnancy test?

A

4-12 weeks

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20
Q

Abdominal enlargement

A

around 14 weeks

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21
Q

Ballottement

A

16-28 weeks

the examiner pushes against the cervix during pelvic exam and feels a rebound from the floating uterus

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22
Q

Goodell’s sign

A

5 weeks

softening of the cervix

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23
Q

Chadwick’s Sign

A

6-9 weeks

vaginal mucosa and cervix take on a bluish color

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24
Q

Hegar’s Sign

A

6-12 weeks

softening of the lower uterine segment

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25
When can an ultra sound verify the embryo?
4-6 weeks
26
When can the physician feel fetal movement?
20 weeks
27
Auscultation of the fetal heart tones via doppler occurs when?
10-12 weeks
28
hCG
the earliest biochemical marker for pregnancy | -usually detectable 5-8 days after conception, but definitely by day 11
29
hCG levels in pregnancy
usually double every 48-72 hours until they peak 60-70 days after fertilization
30
What do physicians use to help differentiate between a normal and abnormal pregnancy?
hCG doubling time
31
Lower levels of hCG may cause?
ectopic pregnancy
32
Higher levels of hCG may cause?
molar pregnancy or multiple-gestational pregnancies
33
What are four other causes of hCG elevation?
Ovarian cancer Choriocarcinoma Hydatidiform mole
34
Choriocarcinoma
a fast growing cancer that grows in the uterus | -abnormal cells start in the tissue that would become the placenta
35
Hydatidiform Mole
a noncancerous tumor that develops in the uterus as a result of a nonviable pregnancy
36
Supine Hypotensive Syndrome
the heavy/gravid uterus can fall back against the inferior vena cava in the supine position, resulting in vena cava compression
37
Symptoms of Supine Hypotensive Syndrome
reduced venous return decreased cardiac output and blood pressure increased orthostatic stress weakness, light headedness, nausea, dizziness, and syncope
38
When a patient is experiencing Symptoms of Supine Hypotensive Syndrome what should you have them do?
instruct them to lie on her left side, which displaces the uterus and pressure is removed from the vena cava
39
What causes Goodell's sign to happen?
the cervix begins to soften due to vasocongestion and the influence of estrogen
40
What will happen along with the cervix softening?
- endo-cervical glands enlarge and increase in number creating more cervical mucous - progesterone causes a thick mucous plug to form - Chadwick's sign
41
What does the cervical mucous plug do?
blocks the cervical os and protects against bacterial invasion
42
How much will the weight of the uterus increase at term?
70 g to 1100-1200
43
How will the capacity of the uterus increase at term?
from 10 mL to 5000 mL or greater
44
As pregnancy progresses how much of the uterine blood flow will go to the placenta?
80-90 %
45
How long will the uterus remain in the pelvic cavity before ascending into the abdomen?
the first 3 months
46
How long are the ovaries enlarged because of increased blood supply?
until approximately 14-16 weeks
47
Why does ovulation stop during pregnancy?
because of elevated levels of estrogen and progesterone
48
When do the ovaries stop becoming active in hormone production for pregnancy?
about weeks 6-7 when the placenta takes over the production of progesterone
49
What happens to the breast during pregnancy?
- begin to grow larger and increase in fullness - become more vascular - nipples and areolas become deeply pigmented - tubercles of Montgomery become prominent
50
When can colostrum be expressed by the breasts?
by the third trimester
51
Colostrum
creamy, yellowish breast fluid that provides nourishment for the breast feeding newborn during the first few days of life
52
Where does the gastrointestinal system begin and end?
begins in the oral cavity and ends in the rectum
53
What happens to the gums during pregnancy?
They become hyperemic, swollen, and friable causing easy bleeding
54
What happens to the saliva during pregnancy?
Becomes more acidic | -some complain of excessive salivation-ptyalism
55
Ptyalism
excessive salivation
56
What two dental diseases are common during pregnancy?
Periodontitis and gingivitis
57
Periodontal disease may cause what?
preeclampsia, low-birthweight, stillbirth, and early onset of neonatal sepsis
58
What may be the cause of ptyalism?
the decrease in unconscious swallowing by the women when nauseated
59
GI Side Effects of pregnancy
constipation heartburn hypercholesterolemia nausea/vomiting
60
What are some causes of constipation during pregnancy?
``` low-fiber food choices reduced fluid intake iron supplements decreased activity level intestinal displacement ```
61
What causes heartburn during pregnancy?
slowed gastric emptying combined with relaxation of cardiac sphincter
62
What can cause hypercholesterolemia?
due to the emptying time of the gallbladder secondary to smooth muscle relaxation caused by increased progesterone
63
What can hypercholesterolemia put the patient at risk for?
gallstones
64
What medication was recently approved by the FDA as the first drug to specifically treat morning sickness?
Diclegis
65
How much will the moms heart rate increase during pregnancy?
25%
66
How much will the moms cardiac output increase?
30-50%
67
How much will blood volume be increased?
1500 mL
68
An increase in what can lead to anemia?
increased plasma volume
69
Why do a lot of women experience physiologic anemia?
because maternal blood volume expansion happens at a larger proportion than the increase in red blood cells
70
What is the criteria for Physiologic Anemia?
- Hemoglobin of 10g or less - Red blood cells 3.5 million/mm3 - Normal morphology w/ central pallor
71
Why is the increase in blood volume necessary?
provides adequate hydration of fetal and maternal tissues, to supply blood flow to perfuse the enlarging uterus, provide a reserve during birth, perfusion of kidneys
72
Why does the heart increase in size?
to accommodate the increased blood volume and cardiac output
73
How much will the heart rate increase between 14-20 weeks?
10-15 bpm
74
What can happen to a woman with preexisting heart conditions?
She may become symptomatic and begin to show signs of decompensation during the time the blood volume peeks
75
When should a mom with preexisting heart conditions be monitored more closely?
between 28-35 weeks
76
What happens to the moms blood pressure during pregnancy?
Declines due to the peripheral vasoconstriction caused by the increased level of progesterone
77
When will you see the blood pressure reach its lowest point?
during mod-pregnancy
78
Why should any significant rise in blood pressure be investigated?
To make sure the mom has not developed gestational hypertension
79
Gestational Hypertension
a clinical diagnosis defined by new onset of systolic BP of 140 mmHg or higher and/or diastolic of 90 mmHg or higher after 20 weeks gestation
80
What changes increase a woman's risk of developing DVT/PE?
- increase in fibrin and fibrinogen levels | - venous stasis secondary to venous pooling
81
Increase in fibrin and fibrinogen levels along with other clotting factors make pregnancy what kind of state?
hypercoagulable
82
What causes the lungs to function differently during pregnancy?
- increased progesterone | - growing uterus pushes lungs up approximately 4 cm above the usual position
83
What will allow for a larger tidal volume?
- increase in diaphragmatic excursion - increase in chest circumference - increase in transverse diameter
84
How much will the mother's oxygen consumption increase due to the requirements of the developing fetus?
30-40%
85
How does a woman's breathing change?
she will breathe more deeply and faster
86
What influences increased vascularity in the respiratory tract and causes congestion?
increased estrogen levels
87
Rising levels of sex hormones and sensitivity to allergens may influence the nasal mucosa causing women to experience what throughout their pregnancy?
nosebleeds, rhinitis and congestion
88
What will allow for increase in blood flow to the kidneys during pregnancy?
Hormones
89
What are the primary changes in the urinary structure during pregnancy? And why do they occur?
Dilation of the renal pelvis and the uterus | -result of increased estrogen and progesterone, pressure from enlarging uterus, and dilation of renal pelvis
90
Why does the glomerular filtration rate (GFR) increase?
because of increased blood flow which leads to increased urine flow
91
What happens to the ureters?
elongate, widen, and become more curved above the pelvic rim
92
When does activity of the kidneys increase and decrease?
increase when lying down and decrease with standing
93
How long can it take after pregnancy for the urinary anatomy to return to normal?
up to 3 months
94
What will happen to the mom's ligaments holding the sacroiliac joint and pubis symphysis in place at 10-12 weeks?
begin to soften and stretch and the articulations between the joints widen and become more mobile
95
What is the purpose of the changes to the sacroiliac joint and pubis symphysis?
increase the size of the pelvic cavity which will make delivery easier
96
What can cause lower back pain?
postural changes coupled with loosening of the sacroiliac joints
97
Lordosis
increase in the normal lumbosacral curve
98
What leads to the "waddle" during pregnancy?
relaxation and increased mobility of joints because of the hormones progesterone and relaxin -increased weight gain can make it worse
99
What causes hyperpigmentation?
increased estrogen, progesterone, and melanocyte-stimulating hormone levels
100
Where do you must commonly see hyperpigmentation?
nipples, areolas, umbilicus, perineum, and axilla
101
Melasma
"Mask of pregnancy" | -increased pigmentation on the face
102
Linea Nigra
skin in the middle of the abdomen that has developed a pigmented line running from the umbilicus to the pubic area
103
Where are varicosities most commonly seen?
legs, vulva, perineum
104
What are varicose veins often the result of?
distention, instability, and poor circulation secondary to prolonged standing or sitting and the heavy gravid uterus placing pressure on the pelvic veins preventing complete venous return
105
Interventions to reduce varicosities
- elevating both legs - avoid prolonged sitting or standing-change positions frequently - resting in left lateral position - walking daily - avoid tight clothing and knee high stockings - TED hose
106
Vascular Spiders
small blood vessels - appear on the neck, thorax, face, and arms - especially obvious in Caucasian women
107
What is the pinker area on the palmer surface of the hands called?
palmer erythema
108
Hair during pregnancy
hair growth declines followed by subsequent hair loss after delivery
109
Nails during pregnancy
- typically grow faster, but are more brittle - whitish discolorations or distal separation of the nailbeds - transverse grooves
110
Thyroid gland
- enlarges and becomes more active - increases TSH during 1st trimester and tapers off within a few weeks after birth - essential for proper brain development
111
Hypothyroidism
will compromise fetal neurologic development
112
Pituitary Gland
- enlarges during pregnancy | - produces multiple hormones
113
Why are FSH and LH most likely blocked during pregnancy?
because of the hCG hormone as well as increased levels of prolactin
114
What is thought to be the reason for morning sickness?
elevated levels of hCG and decreased levels of TSH during the first trimester
115
What inhibits the direct influence of prolactin on the breasts during pregnancy?
high levels of progesterone secreted by the placenta
116
When does lactogenesis begin?
at birth after the placenta is expelled and there is a sharp drop in progesterone
117
Where is prolactin released and what is it in response to?
Released from the anterior pituitary gland in response to suckling by the newborn
118
Oxytocin
responsible for uterine contractions both before and after delivery
119
What is believed to be the initiator of labor?
decrease in progesterone
120
What do contractions lead to?
- cervical thinning and dilation | - exert pressure which helps descend fetus into the pelvis
121
What does oxytocin do for the body after delivery?
causes the myometrium to contract, which decreases blood flow, which decreases the amount of bleeding during and after delivery
122
Pancreas
an exocrine organ which supplies digestive enzymes and buffers
123
How many cell types are in the pancreas and which one produces insulin?
4; beta cells produce insulin
124
How does a women develop gestational diabetes?
she has an inadequate number of beta cells so she may be unable to produce enough insulin and will develop glucose intolerance during pregnancy
125
What regulates carbohydrate and protein metabolism and is helpful with stress?
Cortisol
126
During pregnancy Cortisol will:
- helps keep up the level of glucose - breaks down protein to repair tissues and manufacture enzymes - has anti-insulin, anti-inflammatory, and anti-allergic actions - needed for precursors of adrenaline
127
Immunologic Alterations help prevent what from happening?
the mother's immune system from rejecting the fetus
128
Because of immunologic alterations the mother is more at risk for?
infections such as UTI's and influence the course of chronic disorders such as autoimmune disease
129
Inadequate nutritional intake can result in what?
preterm birth, low birth weight, and congenital anomalies
130
Excessive nutritional intake is connected with?
fetal macrosomia leading to difficult birth, neonatal hypoglycemia, and continued obesity for mom and baby, and metabolic syndrome
131
Normal weight/BMI
BMI = 18.5-24.9 total weight gain = 15-25 lbs.